閉経後女性におけるメタボリック症候群の血漿メタボローム・プロファイリング, 2017 JSOG Best Paper Award (Women's Health section), Japan Society of Obstetrics and Gynecology (JSOG)
Apr 2017
閉経後女性におけるメタボリック症候群の血漿メタボローム・プロファイリング, 2017 JSOG Best Paper Award (Women's Health section), Japan Society of Obstetrics and Gynecology (JSOG)
Nov 2015
閉経後女性におけるメタボリック症候群の血漿メタボローム解析：鶴岡メタボロームコホート研究, The 30th annual meeting of the Japan Society for Menopause and Women’s Health Best Presentation Award, Japan Society for Menopause and Women’s Health (JMWH)
Nov 2015
閉経後女性におけるメタボリック症候群の血漿メタボローム解析：鶴岡メタボロームコホート研究, The 30th annual meeting of the Japan Society for Menopause and Women’s Health Best Presentation Award, Japan Society for Menopause and Women’s Health (JMWH)
IIDA Miho, Harada S, Kurihara A, Fukai K, Kuwabara K, Sugiyama D, Takeuchi A, Okamura T, Akiyama M, Nishiwaki Y, Suzuki A, Hirayama A, Sugimoto M, Soga T, Tomita M, Banno K, Aoki D, Takebayashi T.
Menopause. 23(7) 749-758 Jul 2016 [Refereed]
OBJECTIVE:The aim of the study was to investigate the associations of amino acids and other polar metabolites with metabolic syndrome (MetS) in postmenopausal women in a lean Asian population.
METHODS:The participants were 1,422 female residents ...
Metabolic Profiling of Total Physical Activity and Sedentary Behavior in Community-Dwelling Men.
Fukai K, Harada S, IIDA Miho, Kurihara A, Takeuchi A, Kuwabara K, Sugiyama D, Okamura T, Akiyama M, Nishiwaki Y, Oguma Y, Suzuki A, Suzuki C, Hirayama A, Sugimoto M, Soga T, Tomita M, Takebayashi T.
PLoS One. 14(11 (10)) e0164877 Oct 2016 [Refereed]
Harada S, Hirayama A, Chan Q, Kurihara A, Fukai K, .Iida M, Kato S, Sugiyama D, Kuwabara K, Takeuchi A, Akiyama M, Okamura T, Ebbels TMD, Elliott P, Tomita M, Sato A, Suzuki C, Sugimoto M, Soga T, Takebayashi T
Okawa, R., Banno, K., Iida, M., Yanokura, M., Takeda, T., Iijima, M., Kunitomi-Irie, H., Nakamura, K., Adachi, M., Umene, K., Nogami, Y., Masuda, K., Kobayashi, Y., Tominaga, E. and Aoki, D.
Oncol Lett 14(5) 5107-5113 Nov 2017
Epigenetic regulatory mechanisms are a current focus in studies investigating cancer. Chromatin remodeling alters chromatin structure and regulates gene expression, and aberrant chromatin remodeling is involved in carcinogenesis. AT-rich interacti...
Kobayashi, Y., Kashima, H., Rahmanto, Y. S., Banno, K., Yu, Y., Matoba, Y., Watanabe, K., Iijima, M., Takeda, T., Kunitomi, H., Iida, M., Adachi, M., Nakamura, K., Tsuji, K., Masuda, K., Nomura, H., Tominaga, E. and Aoki, D.
Oncotarget 8(42) 72147-72156 Sep 2017
Drug repositioning is an alternative strategy redirecting existing drugs for new disease. We have previously reported an antitumor effect of statins, antidyslipidemic drugs, on ovarian cancer in vitro and in vivo. In this study, we investigated th...
Kunitomi, H., Banno, K., Yanokura, M., Takeda, T., Iijima, M., Nakamura, K., Iida, M., Adachi, M., Watanabe, K., Matoba, Y., Kobayashi, Y., Tominaga, E. and Aoki, D.
Oncol Lett 14(3) 3297-3301 Sep 2017
The increasing incidence of obesity and diabetes due to changes in diet, earlier menarche, delayed menopause, late marriage, and declining birth rate have resulted in an increase in the number of endometrial cancer cases over the last few decades....
Iijima, M., Banno, K., Okawa, R., Yanokura, M., Iida, M., Takeda, T., Kunitomi-Irie, H., Adachi, M., Nakamura, K., Umene, K., Nogami, Y., Masuda, K., Tominaga, E. and Aoki, D.
Oncol Lett 13(3) 1063-1070 Mar 2017
Cancer typically develops due to genetic abnormalities, but a single gene abnormality cannot completely account for the onset of cancer. The Cancer Genome Atlas (CGA) project was conducted for the cross-sectional genome-wide analysis of numerous g...
Methylation Analysis of DNA Mismatch Repair Genes Using DNA Derived from the Peripheral Blood of Patients with Endometrial Cancer: Epimutation in Endometrial Carcinogenesis.
Takeda T, Banno K, Yanokura M, Adachi M, Iijima M, Kunitomi H, Nakamura K, IIDA Miho, Nogami Y, Umene K, Masuda K, Kobayashi Y, Yamagami W, Hirasawa A, Tominaga E, Susumu N, Aoki D.
Takeda, T., Banno, K., Okawa, R., Yanokura, M., Iijima, M., Irie-Kunitomi, H., Nakamura, K., Iida, M., Adachi, M., Umene, K., Nogami, Y., Masuda, K., Kobayashi, Y., Tominaga, E. and Aoki, D.
Oncol Rep 35(2) 607-13 Feb 2016
The AT-rich interacting domaincontaining protein 1A gene (ARID1A) encodes ARID1A, a member of the SWI/SNF chromatin remodeling complex. Mutation of ARID1A induces changes in expression of multiple genes (CDKN1A, SMAD3, MLH1 and PIK3IP1) via chroma...
Irie, H., Banno, K., Yanokura, M., Iida, M., Adachi, M., Nakamura, K., Umene, K., Nogami, Y., Masuda, K., Kobayashi, Y., Tominaga, E. and Aoki, D.
Oncol Lett 11(2) 1287-1293 Feb 2016
Metformin is a first-line drug used for the treatment of type 2 diabetes. Recently, metformin has been reported to reduce the carcinogenic risk and inhibit tumor cell growth in glioma and breast cancer. The anticancer action of metformin involves ...
ARID1A gene mutation in ovarian and endometrial cancers (Review).
Takeda T, Banno K, Okawa R, Yanokura M, Iijima M, Irie-Kunitomi H, Nakamura K, IIDA Miho, Adachi M, Umene K, Nogami Y, Masuda K, Kobayashi Y, Tominaga E, Aoki D.
Oncology Reports 35(2) 607-613 Feb 2016 [Refereed]
Metformin: A candidate for the treatment of gynecological tumors based on drug repositioning.
Irie H, Banno K, Yanokura M, IIDA Miho, Adachi M, Nakamura K, Umene K, Nogami Y, Masuda K, Kobayashi Y, Tominaga E, Aoki D.
Oncology Letters. 11(2) 1287-1293 Feb 2016 [Refereed]
Fukai, K., Harada, S., Iida, M., Kurihara, A., Takeuchi, A., Kuwabara, K., Sugiyama, D., Okamura, T., Akiyama, M., Nishiwaki, Y., Oguma, Y., Suzuki, A., Suzuki, C., Hirayama, A., Sugimoto, M., Soga, T., Tomita, M. and Takebayashi, T.
PLoS One 11(10) e0164877 2016
OBJECTIVE: Physical activity is known to be preventive against various non-communicable diseases. We investigated the relationship between daily physical activity level and plasma metabolites using a targeted metabolomics approach in a population-...
Umene, K., Yanokura, M., Banno, K., Irie, H., Adachi, M., Iida, M., Nakamura, K., Nogami, Y., Masuda, K., Kobayashi, Y., Tominaga, E. and Aoki, D.
Int J Oncol 46(4) 1498-506 Apr 2015
Aurora kinase A (AURKA) regulates the cell cycle checkpoint and maintains genomic integrity. AURKA is overexpressed in various malignant tumors and its upregulation induces chromosomal instability, which leads to aneuploidy and cell transformation...
Nogami, Y., Banno, K., Irie, H., Iida, M., Masugi, Y., Murakami, K. and Aoki, D.
Anticancer Res 35(4) 2247-53 Apr 2015
AIM: This study investigated whether dual-phase scanning (DPS) with 18-fludeoxyglucose positron emission tomography -computed tomography (FDG PET-CT) improves diagnosis of lymph node metastasis (LNM) in gynecologic malignancies, compared to mono-p...
Aurora kinase A has a significant role as a therapeutic target and clinical biomarker in endometrial cancer.
Umene K, Yanokura M, Banno K, Irie H, Adachi M, IIDA Miho, Nakamura K, Nogami Y, Masuda K, Kobayashi Y, Tominaga E, Aoki D.
International Journal of Oncology 46(4) 1498-1506 Apr 2015
Efficacy of 18-FDG PET-CT Dual-phase Scanning for Detection of Lymph Node Metastasis in Gynecological Cancer.
Nogami Y, Banno K, Irie H, IIDA Miho, Masugi Y, Murakami K, Aoki D.
Kobayashi, Y., Nakamura, K., Nomura, H., Banno, K., Irie, H., Adachi, M., Iida, M., Umene, K., Nogami, Y., Masuda, K., Kisu, I., Ueki, A., Yamagami, W., Kataoka, F., Hirasawa, A., Tominaga, E., Susumu, N. and Aoki, D.
Int J Gynecol Cancer 25(3) 440-6 Mar 2015
OBJECTIVE: Synchronous primary endometrial and ovarian cancers have been an important topic in clinical medicine because it is sometimes difficult to distinguish whether there are 2 primary tumors or a single primary tumor and an associated metast...
Adachi, M., Banno, K., Yanokura, M., Iida, M., Nakamura, K., Nogami, Y., Umene, K., Masuda, K., Kisu, I., Ueki, A., Hirasawa, A., Tominaga, E. and Aoki, D.
Mol Clin Oncol 3(2) 267-273 Mar 2015
Risk-reducing surgery (RRS) is defined as a prophylactic approach with removal of organs at high risk of developing cancer, which is performed in cases without lesions or absence of clinically significant lesions. Hereditary gynecological cancers ...
Clinicopathologic analysis with immunohistochemistry for DNA mismatch repair protein expression in synchronous primary endometrial and ovarian cancers.
Kobayashi Y, Nakamura K, Nomura H, Banno K, Irie H, Adachi M, IIDA Miho, Umene K, Nogami Y, Masuda K, Kisu I, Ueki A, Yamagami W, Kataoka F, Hirasawa A, Tominaga E, Susumu N, Aoki D.
Int J Gynecol Cancer 25(3) 440-446 Mar 2015
Drug Repositioning for Gynecologic Tumors: A New Therapeutic Strategy for Cancer.
Banno K, IIDA Miho, Yanokura M, Irie H, Masuda K, Kobayashi Y, Tominaga E, Aoki D.
The Scientific World Journal 2015(2015) 341362 Feb 2015
MicroRNAS in endometrial cancer: recent advances and potential clinical applications.
Yanokura M, Banno K, Iida M, Irie H, Umene K, IIDA Miho, Masuda K, Kobayashi Y, Tominaga E, Aoki D.
Nogami, Y., Banno, K., Irie, H., Iida, M., Kisu, I., Masugi, Y., Tanaka, K., Tominaga, E., Okuda, S., Murakami, K. and Aoki, D.
Jpn J Clin Oncol 45(1) 26-34 Jan 2015
OBJECTIVE: We studied the diagnostic performance of (18)F-fluoro-2-deoxy-d-glucose-positron emission tomography/computed tomography in cervical and endometrial cancers with particular focus on lymph node metastases. METHODS: Seventy patients with ...
The efficacy of preoperative positron emission tomography-computed tomography (PET-CT) for detection of lymph node metastasis in cervical and endometrial cancer: clinical and pathological factors influencing it.
Nogami Y, Banno K, Irie H, IIDA Miho, Masugi Y, Tanaka K, Tominaga E, Okuda S, Murakami K, Aoki D.
Japanese Journal of Clinical Oncology 45(1) 26-34 Jan 2015
Yanokura, M., Banno, K., Iida, M., Irie, H., Umene, K., Masuda, K., Kobayashi, Y., Tominaga, E. and Aoki, D.
EXCLI J 14 190-8 2015
Endometrial cancer is a common malignant gynecological tumor, but there are few biomarkers that are useful for early and accurate diagnosis and few treatments other than surgery. However, use of microRNAs (miRNAs) that induces gene downregulation ...
Banno, K., Iida, M., Yanokura, M., Irie, H., Masuda, K., Kobayashi, Y., Tominaga, E. and Aoki, D.
ScientificWorldJournal 2015 341362 2015
The goals of drug repositioning are to find a new pharmacological effect of a drug for which human safety and pharmacokinetics are established and to expand the therapeutic range of the drug to another disease. Such drug discovery can be performed...
Risk-reducing surgery in hereditary gynecological cancer: Clinical applications in Lynch syndrome and hereditary breast and ovarian cancer.
Adachi M, Banno K, Yanokura M, IIDA Miho, Nakamura K, Nogami Y, Umene K, Masuda K, Kisu I, Ueki A, Hirasawa A, Tominaga E, Aoki D.
Nakamura, K., Banno, K., Yanokura, M., Iida, M., Adachi, M., Masuda, K., Ueki, A., Kobayashi, Y., Nomura, H., Hirasawa, A., Tominaga, E. and Aoki, D.
Mol Clin Oncol 2(6) 909-916 Nov 2014
Lynch syndrome is a hereditary ovarian cancer with a prevalence of 0.9-2.7%. Lynch syndrome accounts for 10-15% of hereditary ovarian cancers, while hereditary breast and ovarian cancer syndrome accounts for 65-75% of these cancers. The lifetime r...
Features of ovarian cancer in Lynch syndrome (Review).
Nakamura K, Banno K, Yanokura M, IIDA Miho, Adachi M, Masuda K, Ueki A, Kobayashi Y, Nomura H, Hirasawa A, Tominaga E, Aoki D.
Molecular and Clinical Oncology 2(6) 909-916 Nov 2014
Iida, M., Banno, K., Yanokura, M., Nakamura, K., Adachi, M., Nogami, Y., Umene, K., Masuda, K., Kisu, I., Iwata, T., Tanaka, K. and Aoki, D.
Mol Clin Oncol 2(5) 647-655 Sep 2014
Cervical cancer ranks high among the causes of female cancer mortalities and is an important disease in developing and developed countries. Current diagnosis of cervical cancer depends on colposcopy, pathological diagnosis and preoperative diagnos...
Candidate biomarkers for cervical cancer treatment: Potential for clinical practice. (Review)
IIDA Miho, Banno K, Yanokura M, Nakamura K, Adachi M, Nogami Y, Umene K, Masuda K, Kisu I, Iwata T, Tanaka K, Aoki D.
Molecular and Clinical Oncology 2(5) 647-655 Sep 2014
Banno, K., Yanokura, M., Iida, M., Masuda, K. and Aoki, D.
J Obstet Gynaecol Res 40(8) 1957-67 Aug 2014
Endometrial cancer is increasing worldwide and the number of patients with this disease is likely to continue to grow, including younger patients. Many endometrial cancers show estrogen-dependent proliferation, but the carcinogenic mechanisms are ...
Carcinogenic mechanisms of endometrial cancer: involvement of genetics and epigenetics.
Banno K, Yanokura M, IIDA Miho, Masuda K, Aoki D.
Journal of Obstetrics and Gynaecology Research 40(8) 1957-1967 Aug 2014
Application of microRNA in diagnosis and treatment of ovarian cancer.
Banno K, Yanokura M, IIDA Miho, Adachi M, Nakamura K, Nogami Y, Umene K, Masuda K, Kisu I, Nomura H, Kataoka F, Tominaga E, Aoki D.
BioMed Research International 2014(2014) 232817 Apr 2014
Nogami, Y., Iida, M., Banno, K., Kisu, I., Adachi, M., Nakamura, K., Umene, K., Masuda, K., Tominaga, E., Tanaka, K. and Aoki, D.
Anticancer Res 34(2) 585-92 Feb 2014
Positron-emission tomography (PET), a diagnostic imaging technique using an agent labeled with a positron-emitting radionuclide, may facilitate improved diagnosis and treatment in gynecological fields. A combined PET/computerized tomography (CT) s...
Application of FDG-PET in cervical cancer and endometrial cancer: utility and future prospects.
Nogami Y, IIDA Miho, Banno K, Kisu I, Adachi M, Nakamura K, Umene K, Masuda K, Tominaga E, Tanaka K, Aoki D.
Anticancer Research 34(2) 585-592 Feb 2014
MicroRNA in cervical cancer: OncomiRs and tumor suppressor miRs in diagnosis and treatment.
Banno K, IIDA Miho, Yanokura M, Kisu I, Iwata T, Tominaga E, Tanaka K, Aoki D.
The Scientific World Journal 2014(2014) 1780753 Jan 2014
Banno, K., Yanokura, M., Iida, M., Adachi, M., Nakamura, K., Nogami, Y., Umene, K., Masuda, K., Kisu, I., Nomura, H., Kataoka, F., Tominaga, E. and Aoki, D.
Biomed Res Int 2014 232817 2014
Ovarian cancer has a poor prognosis because early detection is difficult and recurrent ovarian cancer is usually drug-resistant. The morbidity and mortality of ovarian cancer are high worldwide and new methods of diagnosis and therapy are needed. ...
Banno, K., Iida, M., Yanokura, M., Kisu, I., Iwata, T., Tominaga, E., Tanaka, K. and Aoki, D.
ScientificWorldJournal 2014 178075 2014
Cervical cancer is a female-specific disease with a high incidence and mortality. MicroRNAs (miRNAs) are implicated in posttranscriptional regulation of gene expression and in the pathogenic mechanisms of cancer, suggesting their importance in dia...
Office management of lost intrauterine devices either with or without strings.
Lin BL, IIDA Miho, Suzuki T, Yabuno A, Kim S, Iwata S, Nagai Y.
Gynecology and Minimally Invasive Therapy 3(1) 15-18 Aug 2013
Removal of endometrial polyps through a small-caliber diagnostic flexible hysteroscope using a Lin polyp snare system.
Lin BL, IIDA Miho, Yabuno A, Higuchi T, Murakoshi Y, Iwata S, Zhao Y.
Gynecology and Minimally Invasive Therapy 2(1) 18-21 Jan 2013
Banno K, IIDA Miho, Farghaly SA, Umene K, Kisu I, Aoki D (Part:Contributor, Novel Therapeutic Agents for Treatment of Endometrial Cancer)
Nova Science Publishers, Inc. 2014 ISBN:9781634631945, 9781634631631
Endometrial cancer is a female genital cancer that occurs frequently in Europe and the United States. Conventional therapy for endometrial cancer does not permit fertility preservation or have effects on advanced and recurrent cancers, and new pha...
