2015年8月31日
Potential use of biological proteins for liver failure therapy
Pharmaceutics
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- ,
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- 巻
- 7
- 号
- 3
- 開始ページ
- 255
- 終了ページ
- 274
- 記述言語
- 英語
- 掲載種別
- 書評論文,書評,文献紹介等
- DOI
- 10.3390/pharmaceutics7030255
- 出版者・発行元
- MDPI AG
Biological proteins have unlimited potential for use as pharmaceutical products due to their various biological activities, which include non-toxicity, biocompatibility, and biodegradability. Recent scientific advances allow for the development of novel innovative protein-based products that draw on the quality of their innate biological activities. Some of them hold promising potential for novel therapeutic agents/devices for addressing hepatic diseases such as hepatitis, fibrosis, and hepatocarcinomas. This review attempts to provide an overview of the development of protein-based products that take advantage of their biological activity for medication, and discusses possibilities for the therapeutic potential of protein-based products produced through different approaches to specifically target the liver (or hepatic cells: hepatocytes, hepatic stellate cells, liver sinusoidal endothelial cells, and Kupffer cells) in the treatment of hepatic diseases.
- ID情報
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- DOI : 10.3390/pharmaceutics7030255
- ISSN : 1999-4923
- SCOPUS ID : 84940748886