劉克約 (Katsuyaku Ryu) - マイポータル

基本情報

所属: 岡山大学医歯薬学総合研究科助教

学位: 医学博士(愛媛大学)

J-GLOBAL ID: 201801004828211963
researchmap会員ID: 7000025278

外部リンク: http://www.cc.okayama-u.ac.jp/pharmaco/

研究キーワード

研究分野

ライフサイエンス / 薬理学 /

経歴

2006年

- 岡山大学医歯薬学総合研究科助教
2006年

- Assistant Professor,Graduate School of Medicine, Dentistry and Pharmaceutical Sciences,Okayama University
1980年 - 1992年

中国医学科学院形成外科麻酔科医師
1980年 - 1992年

Doctor

委員歴

2011年

日本薬理学会, 学術評議員

MISC

Therapeutic potential of an anti-high mobility group box-1 monoclonal antibody in epilepsy

Junli Zhao, Yi Wang, Cenglin Xu, Keyue Liu, Ying Wang, Liying Chen, Xiaohua Wu, Feng Gao, Yi Guo, Junming Zhu …

BRAIN BEHAVIOR AND IMMUNITY 64 308-319 2017年8月
Possible involvement of the HMGB1/RAGE signaling mechanism in the induction of central post-stroke pain induced by acute global cerebral ischemia

Shinichi Harada, Wataru Matsuura, Keyue Liu, Masahiro Nishibori, Shogo Tokuyama

BRAIN RESEARCH 1646 433-440 2016年9月
Involvement of high mobility group box 1 in the development and maintenance of chemotherapy-induced peripheral neuropathy in rats

Takeshi Nishida, Maho Tsubota, Yudai Kawaishi, Hiroki Yamanishi, Natsuki Kamitani, Fumiko Sekiguchi, Hiroyasu Ishikura, Keyue Liu, Masahiro Nishibori, Atsufumi Kawabata

TOXICOLOGY 365 48-58 2016年7月
HMGB1 Translocation After Ischemia in the Ovine Fetal Brain

Jiyong Zhang, Daniel Klufas, Karina Manalo, Kwame Adjepong, Joanne O. Davidson, Guido Wassink, Laura Bennet, Alistair J. Gunn, Edward G. Stopa, Keyue Liu …

JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY 75(6) 527-538 2016年6月
Perineural expression of high-mobility group box-1 contributes to long-lasting mechanical hypersensitivity via matrix metalloprotease-9 up-regulation in mice with painful peripheral neuropathy

Fang Fang Zhang, Norimitsu Morioka, Sakura Harano, Yoki Nakamura, Keyue Liu, Masahiro Nishibori, Kazue Hisaoka-Nakashima, Yoshihiro Nakata

JOURNAL OF NEUROCHEMISTRY 136(4) 837-850 2016年2月
Anti-high mobility group box 1 antibody exerts neuroprotection in a rat model of Parkinson's disease

Tatsuya Sasaki, Keyue Liu, Takashi Agari, Takao Yasuhara, Jun Morimoto, Mihoko Okazaki, Hayato Takeuchi, Atsuhiko Toyoshima, Susumu Sasada, Aiko Shinko …

EXPERIMENTAL NEUROLOGY 275 220-231 2016年1月
Anti-HMGB1 antibody reduces weight gain in mice fed a high-fat diet

V. N. Montes, S. Subramanian, L. Goodspeed, S. A. Wang, M. Omer, A. Bobik, K. Teshigawara, M. Nishibori, A. Chait

NUTRITION & DIABETES 5 1-4 2015年6月
Anti-high mobility group box-1 monoclonal antibody treatment provides protection against influenza A virus (H1N1)-induced pneumonia in mice

Nobuyuki Nosaka, Masato Yashiro, Mutsuko Yamada, Yosuke Fujii, Hirokazu Tsukahara, Keyue Liu, Masahiro Nishibori, Akihiro Matsukawa, Tsuneo Morishima

CRITICAL CARE 19 1-9 2015年6月
Suppression of peritoneal thickening by histamine in a mouse model of peritoneal scraping.

Liu K, Yorozuya T, Adachi N, Motoki A, Ninomiya K, Mabuchi H, Iwamoto N, Nishibori M

Clin Exp Nephrol 19 5 2015年
Voluntary exercise induces neurogenesis in the hypothalamus and ependymal lining of the third ventricle.

Atsuko Niwa, Masahiro Nishibori, Shinichi Hamasaki, Takuro Kobori, Keyue Liu, Hidenori Wake, Shuji Mori, Tadashi Yoshino, Hideo Takahashi

Brain Structure and Function 220(818) 1863-2653 2015年
Glycyrrhizin inhibits traumatic brain injury by reducing HMGB1-RAGE interaction

Yu Okuma, Keyue Liu, Hidenori Wake, Rui Liu, Yoshito Nishimura, Zhong Hui, Kiyoshi Teshigawara, Jun Haruma, Yasuhiko Yamamoto, Hiroshi Yamamoto …

NEUROPHARMACOLOGY 85 18-26 2014年10月
Mannitol enhances therapeutic effects of intra-arterial transplantation of mesenchymal stem cells into the brain after traumatic brain injury

Yu Okuma, Feifei Wang, Atsuhiko Toyoshima, Masahiro Kameda, Tomohito Hishikawa, Koji Tokunaga, Kenji Sugiu, Keyue Liu, Jun Haruma, Masahiro Nishibori …

NEUROSCIENCE LETTERS 554 156-161 2013年10月
Histamine inhibits high mobility group box 1-induced adhesion molecule expression on human monocytes

Hideo Takahashi, Hiroshi Sadamori, Kiyoshi Teshigawara, Atsuko Niwa, Keyue Liu, Hidenori Wake, Shuji Mori, Tadashi Yoshino, Masahiro Nishibori

EUROPEAN JOURNAL OF PHARMACOLOGY 718(1-3) 305-313 2013年10月
Neuropathic Pain in Rats with a Partial Sciatic Nerve Ligation Is Alleviated by Intravenous Injection of Monoclonal Antibody to High Mobility Group Box-1

Yoki Nakamura, Norimitsu Morioka, Hiromi Abe, Fang Fang Zhang, Kazue Hisaoka-Nakashima, Keyue Liu, Masahiro Nishibori, Yoshihiro Nakata

PLOS ONE 8(8) 1-9 2013年8月
Role of cell-cell interactions in high mobility group box 1 cytokine activity in human peripheral blood mononuclear cells and mouse splenocytes

Hideo Kohka Takahashi, Hiroshi Sadamori, Keyue Liu, Hidenori Wake, Shuji Mori, Tadashi Yoshino, Yasuhiko Yamamoto, Hiroshi Yamamoto, Masahiro Nishibori

European Journal of Pharmacology 701(1-3) 194-202 2013年2月15日
Anti-high mobility group box-1 antibody therapy for traumatic brain injury

Yu Okuma, Keyue Liu, Hidenori Wake, Jiyong Zhang, Tomoko Maruo, Isao Date, Tadashi Yoshino, Aiji Ohtsuka, Naoki Otani, Satoshi Tomura …

ANNALS OF NEUROLOGY 72(3) 373-384 2012年9月
Peroxiredoxin family proteins are key initiators of post-ischemic inflammation in the brain

Takashi Shichita, Eiichi Hasegawa, Akihiro Kimura, Rimpei Morita, Ryota Sakaguchi, Ichiro Takada, Takashi Sekiya, Hiroaki Ooboshi, Takanari Kitazono, Toru Yanagawa …

NATURE MEDICINE 18(6) 911-+ 2012年6月
Tumour lineage-homing cell-penetrating peptides as anticancer molecular delivery systems.

Kondo E, Saito K, Tashiro Y, Kamide K, Uno S, Furuya T, Mashita M, Nakajima K, Tsumuraya T, Kobayashi N …

Nat Commun 3(951) 1-13 2012年
Anti-high Mobility Group Box-1 Monoclonal Antibody Protects the Blood-Brain Barrier From Ischemia-Induced Disruption in Rats

Jiyong Zhang, Hideo K. Takahashi, Keyue Liu, Hidenori Wake, Rui Liu, Tomoko Maruo, Isao Date, Tadashi Yoshino, Aiji Ohtsuka, Shuji Mori …

STROKE 42(5) 1420-1428 2011年5月
High-Mobility Group Box Protein 1 Neutralization Reduces Development of Diet-Induced Atherosclerosis in Apolipoprotein E-Deficient Mice

Peter Kanellakis, Alex Agrotis, Tin Soe Kyaw, Christine Koulis, Ingo Ahrens, Shuji Mori, Hideo K. Takahashi, Keyue Liu, Karlheinz Peter, Masahiro Nishibori …

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY 31(2) 313-U188 2011年2月