2016年7月
Web application for genetic modification flux with database to estimate metabolic fluxes of genetic mutants
JOURNAL OF BIOSCIENCE AND BIOENGINEERING
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- 巻
- 122
- 号
- 1
- 開始ページ
- 111
- 終了ページ
- 116
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1016/j.jbiosc.2015.12.001
- 出版者・発行元
- SOC BIOSCIENCE BIOENGINEERING JAPAN
Computational analysis of metabolic fluxes is essential in understanding the structure and function of a metabolic network and in rationally designing genetically modified mutants for an engineering purpose. We had presented the genetic modification flux (GMF) that predicts the flux distribution of a broad range of genetically modified mutants. To enhance the feasibility and usability of GMF, we have developed a web application with a metabolic network database to predict a flux distribution of genetically modified mutants. One hundred and twelve data sets of Escherichia coli, Corynebacterium glutamicum, Saccharomyces cerevisiae, and Chinese hamster ovary were registered as standard models. (C) 2015 The Society for Biotechnology, Japan. All rights reserved.
- リンク情報
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- DOI
- https://doi.org/10.1016/j.jbiosc.2015.12.001
- PubMed
- https://www.ncbi.nlm.nih.gov/pubmed/26777238
- Web of Science
- https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000378659200018&DestApp=WOS_CPL
- URL
- https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84952926538&origin=inward
- ID情報
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- DOI : 10.1016/j.jbiosc.2015.12.001
- ISSN : 1389-1723
- eISSN : 1347-4421
- PubMed ID : 26777238
- Web of Science ID : WOS:000378659200018