Takahito Nakama

Profile Information

Degree: 博士(医学)(九州大学)

Researcher number: 30827556
J-GLOBAL ID: 201801011108341262
researchmap Member ID: 7000025789

Education

Apr, 2012 - Mar, 2016

眼科学, 医学系学府, Kyushu University
Apr, 2002 - Mar, 2008

医学科, 医学部, Kyushu University

Papers

Visual Outcomes Based on Early Response to Anti-Vascular Endothelial Growth Factor Treatment for Diabetic Macular Edema

Yoshito Koyanagi, Shigeo Yoshida, Yoshiyuki Kobayashi, Yuki Kubo, Takahito Nakama, Keijiro Ishikawa, Shintaro Nakao, Toshio Hisatomi, Yasuhiro Ikeda, Yuji Oshima …

Ophthalmologica, 239(2-3) 94-102, Mar 1, 2018 Peer-reviewed
Periostin in vitreoretinal diseases

Yoshida S, Nakama T

Cell Mol Life Sci, 74(23) 4329-4337, Dec, 2017 Peer-reviewed
DNA Methylomes Reveal Biological Networks Involved in Human Eye Development, Functions and Associated Disorders

Berdasco M, Yoshida S, Nakama T

Sci Rep, 7(1) 11762, Sep 18, 2017 Peer-reviewed
Different distributions of M1 and M2 macrophages in a mouse model of laser-induced choroidal neovascularization

Zhou Y, Yoshida S, Nakama T

Mol Med Rep, 15(6) 3949-3956, Jun, 2017 Peer-reviewed
Therapeutic Effect of Novel Single-Stranded RNAi Agent Targeting Periostin in Eyes with Retinal Neovascularization

Takahito Nakama, Shigeo Yoshida, Keijiro Ishikawa, Yuki Kubo, Yoshiyuki Kobayashi, Yedi Zhou, Shintaro Nakao, Toshio Hisatomi, Yasuhiro Ikeda, Kazumasa Takao …

MOLECULAR THERAPY-NUCLEIC ACIDS, 6 279-289, Mar, 2017 Peer-reviewed
Different roles played by periostin splice variants in retinal neovascularization

Takahito Nakama, Shigeo Yoshida, Keijiro Ishikawa, Yoshiyuki Kobayashi, Takaya Abe, Hiroshi Kiyonari, Go Shioi, Naruto Katsuragi, Tatsuro Ishibashi, Ryuichi Morishita …

EXPERIMENTAL EYE RESEARCH, 153 133-140, Dec, 2016 Peer-reviewed
Tenascin-C secreted by transdifferentiated retinal pigment epithelial cells promotes choroidal neovascularization via integrin alpha V

Yoshiyuki Kobayashi, Shigeo Yoshida, Yedi Zhou, Takahito Nakama, Keijiro Ishikawa, Yuki Kubo, Mitsuru Arima, Shintaro Nakao, Toshio Hisatomi, Yasuhiro Ikeda …

LABORATORY INVESTIGATION, 96(11) 1178-1188, Nov, 2016 Peer-reviewed
High-Resolution Imaging by Adaptive Optics Scanning Laser Ophthalmoscopy Reveals Two Morphologically Distinct Types of Retinal Hard Exudates

Yamaguchi M, Nakama T

Sci Rep, 6 33574, Sep 19, 2016 Peer-reviewed
Interleukin-12 inhibits pathological neovascularization in mouse model of oxygen-induced retinopathy

Yedi Zhou, Shigeo Yoshida, Yuki Kubo, Yoshiyuki Kobayashi, Takahito Nakama, Muneo Yamaguchi, Keijiro Ishikawa, Shintaro Nakao, Yasuhiro Ikeda, Tatsuro Ishibashi …

SCIENTIFIC REPORTS, 6 28140, Jun, 2016 Peer-reviewed
Tenascin-C promotes angiogenesis in fibrovascular membranes in eyes with proliferative diabetic retinopathy

Kobayashi Y, Yoshida S, Nakama T

Mol Vis, 22 436-45, Apr 30, 2016 Peer-reviewed
Reduced vitreal concentration of periostin after vitrectomy in patients with proliferative diabetic retinopathy

Takashi Tachibana, Shigeo Yoshida, Yuki Kubo, Yoshiyuki Koayashi, Takahito Nakama, Keijiro Ishikawa, Shintaro Nakao, Kenji Izuhara, Toshihiro Kono, Tatsuro Ishibashi

ACTA OPHTHALMOLOGICA, 94(1) E81-E82, Feb, 2016 Peer-reviewed
Comparison of the Effectiveness of Intravitreal Ranibizumab for Diabetic Macular Edema in Vitrectomized and Nonvitrectomized Eyes

Yoshito Koyanagi, Shigeo Yoshida, Yoshiyuki Kobayashi, Yuki Kubo, Muneo Yamaguchi, Takahito Nakama, Shintaro Nakao, Yasuhiro Ikeda, Yuji Ohshima, Tatsuro Ishibashi …

OPHTHALMOLOGICA, 236(2) 67-73, 2016 Peer-reviewed
Differential improvement of vertical and horizontal metamorphopsia scores after epiretinal membrane vitrectomy with ILM peeling

Takashi Tachibana, Shigeo Yoshida, Yoshiyuki Kobayashi, Takahito Nakama, Keijiro Ishikawa, Akihito Sengoku, Shintaro Nakao, Yuji Oshima, Tatsuro Ishibashi

ACTA OPHTHALMOLOGICA, 93(8) E681-E682, Dec, 2015 Peer-reviewed
M2 Macrophages Enhance Pathological Neovascularization in the Mouse Model of Oxygen-Induced Retinopathy

Yedi Zhou, Shigeo Yoshida, Shintaro Nakao, Takeru Yoshimura, Yoshiyuki Kobayashi, Takahito Nakama, Yuki Kubo, Kohta Miyawaki, Muneo Yamaguchi, Keijiro Ishikawa …

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 56(8) 4767-4777, Jul, 2015 Peer-reviewed
Increased vitreous concentrations of MCP-1 and IL-6 after vitrectomy in patients with proliferative diabetic retinopathy: possible association with postoperative macular oedema

Shigeo Yoshida, Yuki Kubo, Yoshiyuki Kobayashi, Yedi Zhou, Takahito Nakama, Muneo Yamaguchi, Takashi Tachibana, Keijiro Ishikawa, Ryoichi Arita, Shintaro Nakao …

BRITISH JOURNAL OF OPHTHALMOLOGY, 99(7) 960-966, Jul, 2015 Peer-reviewed
Increased expression of M-CSF and IL-13 in vitreous of patients with proliferative diabetic retinopathy: implications for M2 macrophage-involving fibrovascular membrane formation

Shigeo Yoshida, Yoshiyuki Kobayashi, Takahito Nakama, Yedi Zhou, Keijiro Ishikawa, Ryoichi Arita, Shintaro Nakao, Masanori Miyazaki, Yukio Sassa, Yuji Oshima …

BRITISH JOURNAL OF OPHTHALMOLOGY, 99(5) 629-634, May, 2015 Peer-reviewed
Overexpression of CD163 in vitreous and fibrovascular membranes of patients with proliferative diabetic retinopathy: possible involvement of periostin

Kobayashi Y, Yoshida S, Nakama T

Br J Ophthalmol, 99(4) 451-6, Apr, 2015 Peer-reviewed
Microarray Analysis of Gene Expression in Fibrovascular Membranes Excised From Patients With Proliferative Diabetic Retinopathy

Keijiro Ishikawa, Shigeo Yoshida, Yoshiyuki Kobayashi, Yedi Zhou, Takahito Nakama, Shintaro Nakao, Yukio Sassa, Yuji Oshima, Hiroaki Niiro, Koichi Akashi …

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 56(2) 932-946, Feb, 2015 Peer-reviewed
Inhibition of choroidal fibrovascular membrane formation by new class of RNA interference therapeutic agent targeting periostin

T. Nakama, S. Yoshida, K. Ishikawa, Y. Kobayashi, Y. Zhou, S. Nakao, Y. Sassa, Y. Oshima, K. Takao, A. Shimahara …

GENE THERAPY, 22(2) 127-137, Feb, 2015 Peer-reviewed
Periostin promotes the generation of fibrous membranes in proliferative vitreoretinopathy

Keijiro Ishikawa, Shigeo Yoshida, Shintaro Nakao, Takahito Nakama, Takeshi Kita, Ryo Asato, Yukio Sassa, Ryoichi Arita, Masanori Miyazaki, Hiroshi Enaida …

FASEB JOURNAL, 28(1) 131-142, Jan, 2014 Peer-reviewed

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