論文

査読有り 国際誌
2020年

Comparison of Cerebral Blood Flow Patterns in Patients with Phantom Bite Syndrome with Their Corresponding Clinical Features.

Neuropsychiatric disease and treatment
  • Yojiro Umezaki
  • Motoko Watanabe
  • Yukiko Shinohara
  • Shiori Sugawara
  • Kaoru Kawasaki
  • Trang T H Tu
  • Takeshi Watanabe
  • Takayuki Suga
  • Anna Miura
  • Miho Takenoshita
  • Yusuke Sato
  • Ichiro Minami
  • Jun Oyama
  • Akira Toriihara
  • Tatsuya Yoshikawa
  • Toru Naito
  • Haruhiko Motomura
  • Akira Toyofuku
  • 全て表示

16
開始ページ
2277
終了ページ
2284
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.2147/NDT.S262892

Background: Phantom bite syndrome (PBS) is characterized by an uncomfortable sensation during occlusion without any evident abnormality. A recent case-control study with single-photon emission computed tomography (SPECT) using 99mTc-ethyl cysteinate dimer could not find the specific features of regional cerebral blood flow (rCBF), which might be due to the heterogeneity of PBS. We analyzed the brain images of PBS corresponding to the clinical features by studying PBS subgroups. Methods: This study contributes to elucidating the pathophysiology of PBS by evaluating regional brain perfusion on SPECT and its clinical features. We performed SPECT using 99mTc-ethyl cysteinate dimer in 44 patients with PBS. The SPECT images were analyzed qualitatively and quantitatively. Results: Asymmetrical rCBF patterns were detected, corresponding to symptom laterality. Patients with PBS with right-side symptoms showed right-side-predominant rCBF asymmetry in the parietal region and left-side-predominant rCBF asymmetry in the thalamus, and vice versa. Moreover, the analysis of the association between rCBF and patient behaviors revealed that patients who blamed their dentists for their symptoms tended to have a symmetrical rCBF pattern. Conclusion: Patients with PBS showed blood flow imbalance in the thalamus and parietal region corresponding to symptom laterality. There are two types of symmetrical and asymmetrical rCBF patterns in the pathophysiology of PBS despite similar clinical manifestations.

リンク情報
DOI
https://doi.org/10.2147/NDT.S262892
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/33116526
PubMed Central
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7547763
ID情報
  • DOI : 10.2147/NDT.S262892
  • PubMed ID : 33116526
  • PubMed Central 記事ID : PMC7547763

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