論文

査読有り
2011年2月

Pigment-Dispersing Factor Affects Nocturnal Activity Rhythms, Photic Entrainment, and the Free-Running Period of the Circadian Clock in the Cricket Gryllus bimaculatus

JOURNAL OF BIOLOGICAL RHYTHMS
  • Ehab Hassaneen
  • ,
  • Alaa El-Din Sallam
  • ,
  • Ahmad Abo-Ghalia
  • ,
  • Yoshiyuki Moriyama
  • ,
  • Svetlana G. Karpova
  • ,
  • Salah Abdelsalam
  • ,
  • Ayami Matsushima
  • ,
  • Yasuyuki Shimohigashi
  • ,
  • Kenji Tomioka

26
1
開始ページ
3
終了ページ
13
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1177/0748730410388746
出版者・発行元
SAGE PUBLICATIONS INC

Pigment-dispersing factor (PDF) is a neuropeptide widely distributed in insect brains and plays important roles in the circadian system. In this study, we used RNA interference to study the role of the pigment-dispersing factor (pdf) gene in regulating circadian locomotor rhythms in the cricket, Gryllus bimaculatus. Injections of pdf double-stranded RNA (dspdf) effectively knocked down the pdf mRNA and PDF peptide levels. The treated crickets maintained the rhythm both under light-dark cycles (LD) and constant darkness (DD). However, they showed rhythms with reduced nocturnal activity with prominent peaks at lights-on and lights-off. Entrainability of dspdf-injected crickets was higher than control crickets as they required fewer cycles to resynchronize to the LD cycles shifted by 6 h. The free-running periods of the dspdf-injected crickets were shorter than those of control crickets in DD. These results suggest that PDF is not essential for the rhythm generation but involved in control of the nocturnality, photic entrainment, and fine tuning of the free-running period of the circadian clock.

Web of Science ® 被引用回数 : 16

リンク情報
DOI
https://doi.org/10.1177/0748730410388746
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000286424800001&DestApp=WOS_CPL

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