2013年1月
Critical Appraisal of the 1977 Diagnostic Criteria for Minamata Disease
ARCHIVES OF ENVIRONMENTAL & OCCUPATIONAL HEALTH
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- 巻
- 68
- 号
- 1
- 開始ページ
- 22
- 終了ページ
- 29
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1080/19338244.2011.627894
- 出版者・発行元
- ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD
Large-scale food poisoning caused by methylmercury was identified in Minamata, Japan, in the 1950s (Minamata disease). Although the diagnostic criteria for the disease remain current, few studies have been carried out to assess the diagnostic accuracy of the criteria. From a 1971 population-based investigation, data from 2 villages were selected: Minamata (high-exposure area; n = 779) and Ariake (low-exposure area; n = 755). The authors examined the prevalence of neurologic signs characteristic of methylmercury poisoning and the validity of the criteria. A substantial number of residents in the exposed area exhibited neurologic signs even after excluding officially certified patients. Using paresthesia of the extremities as the gold standard of diagnosis, the criteria had a sensitivity of 66%. The current diagnostic criteria as well as the official certification system substantially underestimate the incidence of Minamata disease.
- リンク情報
- ID情報
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- DOI : 10.1080/19338244.2011.627894
- ISSN : 1933-8244
- Web of Science ID : WOS:000313614900004