尾上剛史 (Takeshi Onoue) - マイポータル

基本情報

所属: 名古屋大学医学部附属病院卒後臨床研修・キャリア形成支援センター病院助教

学位: 博士（医学）(名古屋大学)

研究者番号: 60809812
J-GLOBAL ID: 201801001502440718
researchmap会員ID: 7000028152

研究キーワード

研究分野

ライフサイエンス / 代謝、内分泌学 /

経歴

2017年4月 - 現在

名古屋大学, 医学部附属病院卒後臨床研修・キャリア形成支援センター, 病院助教

学歴

- 2016年

名古屋大学, 医学系研究科
- 2007年3月

名古屋大学, 医学部, 医学科

論文

Chemical chaperone 4-phenylbutylate reduces mutant protein accumulation in the endoplasmic reticulum of arginine vasopressin neurons in a mouse model for familial neurohypophysial diabetes insipidus

Masayoshi Tochiya, Daisuke Hagiwara, Yoshinori Azuma, Takashi Miyata, Yoshiaki Morishita, Hidetaka Suga, Takeshi Onoue, Taku Tsunekawa, Hiroshi Takagi, Yoshihiro Ito …

Neuroscience Letters 682 50-55 2018年8月24日
Patients With Antithyroid Antibodies Are Prone To Develop Destructive Thyroiditis by Nivolumab: A Prospective Study

Kobayashi Tomoko, Iwama Shintaro, Yasuda Yoshinori, Okada Norio, Tsunekawa Taku, Onoue Takeshi, Takagi Hiroshi, Hagiwara Daisuke, Ito Yoshihiro, Morishita Yoshiaki …

JOURNAL OF THE ENDOCRINE SOCIETY 2(3) 241-251-251 2018年3月
Randomized controlled trial for assessment of Internet of Things system to guide intensive glucose control in diabetes outpatients: Nagoya Health Navigator Study protocol

Takeshi Onoue, Motomitsu Goto, Tomoko Kobayashi, Takashi Tominaga, Masahiko Ando, Hiroyuki Honda, Yasuko Yoshida, Takahiro Tosaki, Hisashi Yokoi, Sawako Kato …

NAGOYA JOURNAL OF MEDICAL SCIENCE 79(3) 323-329 2017年8月
Sequestosome 1 (SQSTMI/p62) maintains protein folding capacity under endoplasmic reticulum stress in mouse hypothalamic organotypic culture

Takashi Tominaga, Motomitsu Goto, Takeshi Onoue, Akira Mizoguchi, Mariko Sugiyama, Taku Tsunekawa, Daisuke Hagiwara, Yoshiaki Morishita, Yoshihiro Ito, Shintaro Iwama …

NEUROSCIENCE LETTERS 656 103-107 2017年8月
PTP1B deficiency improves hypothalamic insulin sensitivity resulting in the attenuation of AgRP mRNA expression under high-fat diet conditions

Mariko Sugiyama, Ryoichi Banno, Akira Mizoguchi, Takashi Tominaga, Taku Tsunekawa, Takeshi Onoue, Daisuke Hagiwara, Yoshihiro Ito, Yoshiaki Morishita, Shintaro Iwama …

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 488(1) 116-121 2017年6月
Deficiency of PTP1B Attenuates Hypothalamic Inflammation via Activation of the JAK2-STAT3 Pathway in Microglia

Taku Tsunekawa, Ryoichi Banno, Akira Mizoguchi, Mariko Sugiyama, Takashi Tominaga, Takeshi Onoue, Daisuke Hagiwara, Yoshihiro Ito, Shintaro Iwama, Motomitsu Goto …

EBIOMEDICINE 16 172-183 2017年2月
AgRP Neuron-Specific Deletion of Glucocorticoid Receptor Leads to Increased Energy Expenditure and Decreased Body Weight in Female Mice on a High-Fat

Miyuki Shibata, Ryoichi Banno, Mariko Sugiyama, Takashi Tominaga, Takeshi Onoue, Taku Tsunekawa, Yoshinori Azuma, Daisuke Hagiwara, Wenjun Lu, Yoshihiro Ito …

ENDOCRINOLOGY 157(4) 1457-1466 2016年4月
Reactive oxygen species mediate insulin signal transduction in mouse hypothalamus

Takeshi Onoue, Motomitsu Goto, Takashi Tominaga, Mariko Sugiyama, Taku Tsunekawa, Daisuke Hagiwara, Ryoichi Banno, Hidetaka Suga, Yoshihisa Sugimura, Hiroshi Arima

NEUROSCIENCE LETTERS 619 1-7 2016年4月
Reactive oxygen species mediate insulin signal transduction in mouse hypothalamus.

Onoue T, Goto M, Tominaga T, Sugiyama M, Tsunekawa T, Hagiwara D, Banno R, Suga H, Sugimura Y, Arima H

Neurosci. Letters (619) 1-7 2016年査読有り
MAPK Signaling Is Inhibited By Mitogen-Activated Protein Kinase Phosphatase 1 in Mouse Hypothalamus

Adachi Koichi, Goto Motomitsu, Onoue Takeshi, Tsunekawa Taku, Shibata Miyuki, Hagimoto Shigeru, Ito Yoshihiro, Banno Ryoichi, Suga Hidetaka, Sugimura Yoshihisa …

ENDOCRINE REVIEWS 35(3) . 2014年6月
Insulin-Induced Phosphorylation of Akt Is Mediated Via NADPH Oxidase-Derived Reactive Oxygen Species in the Mouse Hypothalamic Organotypic Cultures

Onoue Takeshi, Goto Motomitsu, Tsunekawa Taku, Shibata Miyuki, Adachi Koichi, Ito Yoshihiro, Bonno Ryoichi, Arima Hiroshi, Oiso Yutaka

ENDOCRINE REVIEWS 35(3) . 2014年6月
Agrp Neuron-Specific Deletion of Glucocorticoid Receptor Leads to Decreased Body Weight and Adiposity in Mice

Shibata Miyuki, Banno Ryoichi, Onoue Takeshi, Tsunekawa Taku, Adachi Koichi, Ito Yoshihiro, Goto Motomitsu, Arima Hiroshi, Oiso Yutaka

ENDOCRINE REVIEWS 35(3) . 2014年6月
Mitogen-activated protein kinase phosphatase 1 negatively regulates MAPK signaling in mouse hypothalamus

Koichi Adachi, Motomitsu Goto, Takeshi Onoue, Taku Tsunekawa, Miyuki Shibata, Shigeru Hagimoto, Yoshihiro Ito, Ryoichi Banno, Hidetaka Suga, Yoshihisa Sugimura …

NEUROSCIENCE LETTERS 569 49-54 2014年5月

MISC

Chemical chaperone 4-phenylbutylate reduces mutant protein accumulation in the endoplasmic reticulum of arginine vasopressin neurons in a mouse model for familial neurohypophysial diabetes insipidus

Masayoshi Tochiya, Daisuke Hagiwara, Yoshinori Azuma, Takashi Miyata, Yoshiaki Morishita, Hidetaka Suga, Takeshi Onoue, Taku Tsunekawa, Hiroshi Takagi, Yoshihiro Ito …

Neuroscience Letters 682 50-55 2018年8月24日
Patients With Antithyroid Antibodies Are Prone To Develop Destructive Thyroiditis by Nivolumab: A Prospective Study

Kobayashi Tomoko, Iwama Shintaro, Yasuda Yoshinori, Okada Norio, Tsunekawa Taku, Onoue Takeshi, Takagi Hiroshi, Hagiwara Daisuke, Ito Yoshihiro, Morishita Yoshiaki …

JOURNAL OF THE ENDOCRINE SOCIETY 2(3) 241-251-251 2018年3月
Randomized controlled trial for assessment of Internet of Things system to guide intensive glucose control in diabetes outpatients: Nagoya Health Navigator Study protocol

Takeshi Onoue, Motomitsu Goto, Tomoko Kobayashi, Takashi Tominaga, Masahiko Ando, Hiroyuki Honda, Yasuko Yoshida, Takahiro Tosaki, Hisashi Yokoi, Sawako Kato …

NAGOYA JOURNAL OF MEDICAL SCIENCE 79(3) 323-329 2017年8月
Sequestosome 1 (SQSTMI/p62) maintains protein folding capacity under endoplasmic reticulum stress in mouse hypothalamic organotypic culture

Takashi Tominaga, Motomitsu Goto, Takeshi Onoue, Akira Mizoguchi, Mariko Sugiyama, Taku Tsunekawa, Daisuke Hagiwara, Yoshiaki Morishita, Yoshihiro Ito, Shintaro Iwama …

NEUROSCIENCE LETTERS 656 103-107 2017年8月
PTP1B deficiency improves hypothalamic insulin sensitivity resulting in the attenuation of AgRP mRNA expression under high-fat diet conditions

Mariko Sugiyama, Ryoichi Banno, Akira Mizoguchi, Takashi Tominaga, Taku Tsunekawa, Takeshi Onoue, Daisuke Hagiwara, Yoshihiro Ito, Yoshiaki Morishita, Shintaro Iwama …

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 488(1) 116-121 2017年6月
Deficiency of PTP1B Attenuates Hypothalamic Inflammation via Activation of the JAK2-STAT3 Pathway in Microglia

Taku Tsunekawa, Ryoichi Banno, Akira Mizoguchi, Mariko Sugiyama, Takashi Tominaga, Takeshi Onoue, Daisuke Hagiwara, Yoshihiro Ito, Shintaro Iwama, Motomitsu Goto …

EBIOMEDICINE 16 172-183 2017年2月
Reactive oxygen species mediate insulin signal transduction in mouse hypothalamus.

Onoue T, Goto M, Tominaga T, Sugiyama M, Tsunekawa T, Hagiwara D, Banno R, Suga H, Sugimura Y, Arima H

Neurosci. Letters (619) 1-7 2016年査読有り

講演・口頭発表等

IoTを用いた生活習慣病へのアプローチ

尾上剛史, 津下一代, 有馬寛

第40回日本肥満学会 2019年11月2日招待有り
Randomized controlled trial to evaluate the effects of anaglipitin, a DPP-4 inhibitor, on blood lipids in type 2 diabetic patients

Takeshi Onoue, Mariko Furukawa, Eri Wada, Norio Okada, Tomoko Kobayashi, Shintaro Iwama, Motomitsu Goto, Masahiko Ando, Hiroshi Arima

第101回米国内分泌学会 2019年3月23日
Randomized controlled trial for assessment of Internet of Things system to guide intensive glucose control in diabetes outpatients: Nagoya Health Navigator Study

Onoue T

第100回米国内分泌学会 2018年3月17日
IoT(Internet of things)システムを用いた療養指導強化による糖代謝改善についての検討-クリニック通院患者を対象とした前向き研究-

尾上剛史

第60回日本糖尿病学会年次学術集会 2017年5月18日
NADPH oxidase-derived reactive oxygen species (ROS) enhance insulin signaling in mouse hypothalamus

Onoue T, Goto M, Tsunekawa T, Shibata M, Adachi K, Ito Y, Banno R, Arima H, Oiso Y

第96回米国内分泌学会 2014年6月21日

担当経験のある科目(授業)

PBL (Nagoya University)
PBL (名古屋大学)

所属学協会

共同研究・競争的資金等の研究課題

壮年期就労者を対象とした生活習慣病予防のための動機付け支援の技術開発に関する研究

日本医療研究開発機構循環器疾患・糖尿病等生活習慣病対策実用化研究事業 2019年4月 - 2021年3月