MAKOKHA NASWA GRACE (NASWA GRACE MAKOKHA) - マイポータル

基本情報

所属: 公益財団法人広島生命科学研究所

研究者番号: 50736006
J-GLOBAL ID: 201801019521270455
researchmap会員ID: 7000028419

研究分野

ライフサイエンス / 応用分子細胞生物学 /

経歴

2024年4月 - 現在

公益財団法人広島生命科学研究所, 研究員
2021年4月 - 2024年3月

広島大学, 医系科学研究科医療イノベーション共同研究講座, 特任助教
2017年4月 - 2021年3月

大学院医歯薬保健学研究院, 特任助教
2015年4月 - 2017年3月

広島大学, 大学院医歯薬保健学研究院, 助教
2014年4月 - 2015年3月

広島大学, 大学院医歯薬保健学研究院, 研究員

学歴

2009年10月 - 2013年9月

新潟大学, 大学院医歯薬学総合研究科, 地域疾病制御医学専攻博士課程
2002年1月 - 2006年12月

Maseno University, BiomedicalSciences, Biomedical Sciences and Technology

論文

The Prevalence and Risk Factors of Hepatitis B, Hepatitis C, and Hepatitis D Coinfection in Iran's General Population Over the Past 25 Years: A Systematic Review and Meta-Analysis.

Malihe Naderi, Kosar Kordkatuli, Grace Naswa Makokha, Abdolvahab Moradi, Fatemeh Mehravar, Makoto Hijikata, Kazuaki Chayama

Journal of epidemiology and global health 16(1) 2-2 2025年12月28日
What is the future of Mpox outbreak?

Grace Naswa Makokha, Maidina Abuduwaili, Kazuaki Chayama, Makoto Hijikata

Virology 610 110618-110618 2025年9月
The Prevalence and Genotype Distribution of Hepatitis C Virus in Kenya: A Systematic Review and Meta-Analysis.

Grace Naswa Makokha, Huarui Bao, C Nelson Hayes, Maidina Abuduwaili, Elijah Songok, Makoto Hijikata, Kazuaki Chayama

Journal of epidemiology and global health 14(3) 677-689 2024年9月
Deficiency of SCAP inhibits HBV pathogenesis via activation of the interferon signaling pathway.

Grace Naswa Makokha, Kazuaki Chayama, C Nelson Hayes, Hiromi Abe-Chayama, Maidina Abuduwaili, Makoto Hijikata

Virology 585 248-258 2023年8月
A novel cDNA-uPA/SCID/Rag2-/- /Jak3-/- mouse model for hepatitis virus infection and reconstruction of human immune system.

Takuro Uchida, Yuji Teraoka, Michio Imamura, Hiromi Abe-Chayama, Grace Naswa Makokha, Clair Nelson Hayes, Hiroshi Aikata, Satoko Hamamura, Yuji Ishida, Chise Tateno …

Journal of viral hepatitis 30(3) 262-272 2023年3月
The burden of Hepatitis B virus infection in Kenya: A systematic review and meta-analysis.

Grace Naswa Makokha, Peiyi Zhang, C Nelson Hayes, Elijah Songok, Kazuaki Chayama

Frontiers in public health 11 986020-986020 2023年
The presence of vessels encapsulating tumor clusters is associated with an immunosuppressive tumor microenvironment in hepatocellular carcinoma.

Peiyi Zhang, Atsushi Ono, Yasutoshi Fujii, Clair Nelson Hayes, Yosuke Tamura, Ryoichi Miura, Yuki Shirane, Hikaru Nakahara, Masami Yamauchi, Shinsuke Uchikawa …

International journal of cancer 151(12) 2278-2290 2022年12月15日
Construction of an anti-hepatitis B virus preS1 antibody and usefulness of preS1 measurement for chronic hepatitis B patients: Anti-HBV PreS1 antibody.

Haruna Hatooka, Yumi Shimomura, Michio Imamura, Yuji Teraoka, Kei Morio, Hatsue Fujino, Atsushi Ono, Takashi Nakahara, Eisuke Murakami, Masami Yamauchi …

The Journal of infection 84(3) 391-399 2022年3月査読有り
HBV upregulates TRAIL-R3 expression in hepatocytes for escaping both cell apoptosis and suppression of their replication by TRAIL.

Yosuke Suehiro, Masataka Tsuge, Mio Kurihara, Takuro Uchida, Hatsue Fujino, Atsushi Ono, Masami Yamauchi, Grace Naswa Makokha, Takashi Nakahara, Eisuke Murakami …

The Journal of infectious diseases 2022年2月28日
In vitro analysis of hepatic stellate cell activation influenced by transmembrane 6 superfamily 2 polymorphism.

Songyao Liu, Eisuke Murakami, Takashi Nakahara, Kazuki Ohya, Yuji Teraoka, Grace Naswa Makokha, Takuro Uchida, Kei Morio, Hatsue Fujino, Atsushi Ono …

Molecular medicine reports 23(1) 2021年1月査読有り
Signal Activation of Hepatitis B Virus-Related Hepatocarcinogenesis by Up-regulation of SUV39h1

Takeuchi, Yasue, Tsuge, Masataka, Tsushima, Ken, Suehiro, Yosuke, Fujino, Hatsue, Ono, Atsushi, Yamauchi, Masami, Makokha, Grace Naswa, Nakahara, Takashi, Murakami, Eisuke …

JOURNAL OF INFECTIOUS DISEASES 222(12) 2061-2070 2020年12月15日査読有り
Circulating cytokines and angiogenic factors based signature associated with the relative dose intensity during treatment in patients with advanced hepatocellular carcinoma receiving lenvatinib.

Atsushi Ono, Hiroshi Aikata, Masami Yamauchi, Kenichiro Kodama, Waka Ohishi, Takeshi Kishi, Kazuki Ohya, Yuji Teraoka, Mitsutaka Osawa, Hatsue Fujino …

Therapeutic advances in medical oncology 12 1758835920922051-1758835920922051 2020年5月査読有り
Efficacy of glecaprevir and pibrentasvir treatment for genotype 1b hepatitis C virus drug resistance-associated variants in humanized mice

Osawa, Mitsutaka, Uchida, Takuro, Imamura, Michio, Teraoka, Yuji, Fujino, Hatsue, Nakahara, Takashi, Ono, Atsushi, Murakami, Eisuke, Kawaoka, Tomokazu, Miki, Daiki …

JOURNAL OF GENERAL VIROLOGY 100(7) 1123-1131 2019年7月査読有り
Comparison of intracellular responses between HBV genotype A and C infection in human hepatocyte chimeric mice

Tsushima, Ken, Tsuge, Masataka, Hiraga, Nobuhiko, Uchida, Takuro, Murakami, Eisuke, Makokha, Grace Naswa, Kurihara, Mio, Nomura, Motonobu, Hiyama, Yuichi …

JOURNAL OF GASTROENTEROLOGY 54(7) 650-659 2019年7月査読有り
Regulation of the Hepatitis B virus replication and gene expression by the multi-functional protein TARDBP.

Grace Naswa Makokha, Hiromi Abe-Chayama, Sajeda Chowdhury, C Nelson Hayes, Masataka Tsuge, Tadahiko Yoshima, Yuji Ishida, Yizhou Zhang, Takuro Uchida, Chise Tateno …

Scientific reports 9(1) 8462-8462 2019年6月11日
Regulation of the Hepatitis B virus replication and gene expression by the multi-functional protein TARDBP

Makokha, Grace Naswa, Abe-Chayama, Hiromi, Chowdhury, Sajeda, Hayes, C. Nelson, Tsuge, Masataka, Yoshimaz, Tadahiko, Ishida, Yuji, Zhang, Yizhou, Uchida, Takuro …

SCIENTIFIC REPORTS 9(1) 2233-2233 2019年6月11日査読有り
Endoplasmic reticulum-mediated induction of interleukin-8 occurs by hepatitis B virus infection and contributes to suppression of interferon responsiveness in human hepatocytes

Tsuge, Masataka, Hiraga, Nobuhiko, Zhang, Yizhou, Yamashita, Misa, Sato, Ojiro, Oka, Naoya, Shiraishi, Kanma, Izaki, Yu f, Makokha, Grace Naswa, Uchida, Takuro …

VIROLOGY 525 48-61 2018年12月査読有り
Limitations of daclatasvir/asunaprevir plus beclabuvir treatment in cases of NS5A inhibitor treatment failure

Teraoka, Yuji, Uchida, Takuro, Imamura, Michio, Hiraga, Nobuhiko, Osawa, Mitsutaka, Kan, Hiromi, Saito, Yuhei, Tsuge, Masataka, Abe-Chayama, Hiromi, Hayes, C. Nelson …

JOURNAL OF GENERAL VIROLOGY 99(8) 1058-1065 2018年8月査読有り
Prevalence of NS5A resistance associated variants in NS5A inhibitor treatment failures and an effective treatment for NS5A-P32 deleted hepatitis C virus in humanized mice

Yuji Teraoka, Takuro Uchida, Michio Imamura, Mitsutaka Osawa, Masataka Tsuge, Hiromi Abe-Chayama, C. Nelson Hayes, Grace Naswa Makokha, Hiroshi Aikata, Daiki Miki …

Biochemical and Biophysical Research Communications 500(2) 152-157 2018年6月2日査読有り
Erratum to: Serum HMGB1 concentrations at 4 weeks is a useful predictor of extreme poor prognosis for advanced hepatocellular carcinoma treated with sorafenib and hepatic arterial infusion chemotherapy.

Kazuhiko Masuda, Atsushi Ono, Hiroshi Aikata, Tomokazu Kawaoka, C Nelson Hayes, Yuji Teraoka, Kana Daijo, Yuki Nakamura-Inagaki, Kei Morio, Hatsue Fujino …

Journal of gastroenterology 53(1) 161-162 2018年1月

もっとみる

MISC

RESISTANCE ANALYSIS FOR GLECAPREVIR AND PIBRENTASVIR ON GENOTYPE 1b HEPATITIS C VIRUS INFECTION IN SUBGENOMIC REPLICON SYSTEMS AND HUMAN HEPATOCYTE TRANSPLANTED MICE

Mitsutaka Osawa, Michio Imamura, Takuro Uchida, Yuji Teraoka, Hatsue Fujino, Takashi Nakahara, Atsushi Ono, Eisuke Murakami, Tomokazu Kawaoka, Daiki Miki …

HEPATOLOGY 70 988A-989A 2019年10月
GENETIC POLYMORPHISM OF IP-10, NOT IFNL4 OR HLA-DPS, AFFECTS LIVER INFLAMMATION IN CHRONIC HEPATITIS B PATIENTS

Daiki Miki, Masataka Tsuge, Hiromi Abe-Chayama, Nelson Hayes, Hatsue Fujino, Grace Naswa Makokha, Atsushi Ono, Takashi Nakahara, Eisuke Murakami, Masami Yamauchi …

HEPATOLOGY 70 412A-413A 2019年10月
ASSOCIATION OF FNDC5, PNPLA3 AND TM6SF2 POLYMORPHISMS WITH HEPATIC STEATOSIS IN NAFLD PATIENTS

Daiki Miki, Takashi Nakahara, Eisuke Murakami, Hiromi Abe-Chayama, Hatsue Fujino, Atsushi Ono, Masami Yamauchi, Tomokazu Kawaoka, Masataka Tsuge, Akira Hiramatsu …

HEPATOLOGY 70 1050A-1051A 2019年10月
A COMPREHENSIVE ANALYSIS OF A WIDE RANGE OF LIVER DISEASES BY 16S rRNA SEQUENCING REVEALS CHARACTERISTIC PATTERNS OF GUT MICROBIOTA IN EACH ETIOLOGY

Daiki Miki, Yumi Shimomura, Nelson Hayes, Hiromi Abe-Chayama, Hatsue Fujino, Maiko Numba, Takashi Nakahara, Atsushi Ono, Eisuke Murakami, Masami Yamauchi …

HEPATOLOGY 70 1163A-1164A 2019年10月
INDEPENDENT IMPACT OF POLYMORPHISM IN IRF5 AS WELL AS STAT4 ON HBV-RELATED HEPATOCARCINOGENESIS

Daiki Miki, Masataka Tsuge, Hiromi Abe-Chayama, Nelson Hayes, Hatsue Fujino, Grace Naswa Makokha, Atsushi Ono, Takashi Nakahara, Eisuke Murakami, Masami Yamauchi …

HEPATOLOGY 70 1190A-1190A 2019年10月
DIFFERENTIAL EFFECTS OF HOST GENETIC FACTORS ON HCV PERSISTENCE ACCORDING TO HCV GENOTYPES

Daiki Miki, Tomokazu Kawaoka, Nelson Hayes, Hiromi Abe-Chayama, Hatsue Fujino, Grace Naswa Makokha, Atsushi Ono, Takashi Nakahara, Eisuke Murakami, Masami Yamauchi …

HEPATOLOGY 70 1008A-1008A 2019年10月
Regulation of the Hepatitis B Virus Gene Expression and Replication By the Multi-Functional Protein Tardbp

Grace Naswa Makokha, Kazuaki Chayama, Hiromi Abe-Chayama, Masataka Tsuge, Takuro Uchida, Yuji Ishida

HEPATOLOGY 68 318A-318A 2018年10月
Efficacy of Glecaprevir and Pibrentasvir Treatment for Hepatitis C Virus Drug Resistance-Associated Variants in Humanized Mice

Mitsutaka Osawa, Takuro Uchida, Michio Imamura, Yuji Teraoka, Masataka Tsuge, Hiromi Abe-Chayama, Grace Naswa Makokha, Hiroshi Aikata, Yuji Ishida, Chise Tateno …

HEPATOLOGY 68 411A-412A 2018年10月
Prevalence of NS5A Resistance Associated Variants in NS5A Inhibitor Treatment Failures and an Effective Treatment for NS5A-P32 Deleted Hepatitis C Virus in Humanized Mice

Yuji Teraoka, Takuro Uchida, Michio Imamura, Mitutaka Osawa, Tomokazu Kawaoka, Masataka Tsuge, Hiromi Abe-Chayama, Nelson Hayes, Grace Naswa Makokha, Hiroshi Aikata …

HEPATOLOGY 68 384A-384A 2018年10月
The Influence of Histone Methyltransferase SUV39h1 on Hepatitis B Virus-Related Hepatocarcinogenesis

Ken Tsushima, Masataka Tsuge, Takuro Uchida, Michio Imamura, Mitutaka Osawa, Yuji Teraoka, Hiromi Abe-Chayama, Grace Naswa Makokha, Hiroshi Aikata, Kazuaki Chayama

HEPATOLOGY 68 328A-329A 2018年10月
A Novel Jak3KORag2KO Chimeric Mouse Model for the Study of Hepatitis Virus Virology

Takuro Uchida, Michio Imamura, Yuji Ishida, Chise Tateno, Mitsutaka Osawa, Yuji Teraoka, Masataka Tsuge, Hiromi Abe-Chayama, Grace Naswa Makokha, Hiroshi Aikata …

HEPATOLOGY 68 587A-587A 2018年10月
Persistent Loss of HBV Markers in Serum without Cellular Immunity by Combination of PEG-IFN Plus ETV Therapy in Humanized Mice

Takuro Uchida, Michio Imamura, C. Nelson Hayes, Nobuhiko Hiraga, Masataka Tsuge, Hiromi Abe-Chayama, Grace N. Makokha, Yuji Ishida, Chise Tateno, Kazuaki Chayama

HEPATOLOGY 66 789A-789A 2017年10月
TARDBP regulates HBV transcription and replication through interaction with the core promoter

Grace N. Makokha, Hiromi Abe-Chayama, Masataka Tsuge, Nelson Hayes, Takuro Uchida, Tadahiko Yoshima, Yuji Ishida, Kazuaki Chayama

HEPATOLOGY 66 784A-785A 2017年10月

所属学協会

2023年4月 - 現在

世界ウイルス学会
2017年10月 - 現在

Japan Society of Hepatology
2012年3月

Japanese Cancer Association

MAKOKHA NASWA GRACE

基本情報

研究分野

経歴

学歴

論文

MISC

所属学協会

メニュー

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