中嶌岳郎 (Takero NAKAJIMA) - マイポータル

基本情報

所属: 信州大学医学部　医学教育研修センター助教

学位: 博士（医学）(2009年3月信州大学)
修士（農学）(2005年3月信州大学)

J-GLOBAL ID: 201801013195750168
researchmap会員ID: 7000028473

研究キーワード

研究分野

経歴

2010年4月

現職
2009年4月 - 2010年3月

日本学術振興会特別研究員PD
2008年4月 - 2009年3月

日本学術振興会特別研究員DC2

学歴

- 2009年3月

信州大学
- 2005年3月

信州大学
- 2003年3月

近畿大学

論文

Establishment of Novel Mouse Model of Dietary NASH Rapidly Progressing into Liver Cirrhosis and Tumors.

Zheng Q, Kawaguchi M, Mikami H, Diao P, Zhang X, Zhang Z, Nakajima T, Iwadare T, Kimura T, Nakayama J, and Tanaka N.

Cancers 15(14) 3744-3744 2023年査読有り
多機能性分子・硫酸化糖脂質の機能と制御

中嶌岳郎、田中直樹

信州医学雑誌 71(3) 137-147 2023年査読有り筆頭著者責任著者
Clinically Relevant Dose of Pemafibrate, a Novel Selective Peroxisome Proliferator-Activated Receptor alpha Modulator (SPPARM alpha), Lowers Serum Triglyceride Levels by Targeting Hepatic PPAR alpha in Mice

Zhang, Zhe, Diao, Pan, Zhang, Xuguang, Nakajima, Takero, Kimura, Takefumi, Tanaka, Naoki

BIOMEDICINES 10(7) 1667 2022年7月
Serum Sulfatide Levels as a Biomarker of Active Glomerular Lesion in Patients with Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis: A Single Center Pilot Study

Harada, Makoto, Nakajima, Takero, Yamada, Yosuke, Aomura, Daiki, Yamaguchi, Akinori, Sonoda, Kosuke, Tanaka, Naoki, Hashimoto, Koji, Kamijo, Yuji

JOURNAL OF CLINICAL MEDICINE 11(3) 762 2022年2月
Acidic Activated Charcoal Prevents Obesity and Insulin Resistance in High-Fat Diet-Fed Mice

Zhang, Xuguang, Diao, Pan, Yokoyama, Hiroaki, Inoue, Yoshiki, Tanabe, Kazuhiro, Wang, Xiaojing, Hayashi, Chihiro, Yokoyama, Tomoki, Zhang, Zhe, Hu, Xiao …

FRONTIERS IN NUTRITION 9 852767 2022年
Mechanisms of Steatosis-Derived Hepatocarcinogenesis: Lessons from HCV Core Gene Transgenic Mice

Diao, Pan, Jia, Fangping, Wang, Xiaojing, Hu, Xiao, Kimura, Takefumi, Nakajima, Takero, Aoyama, Toshifumi, Moriya, Kyoji, Koike, Kazuhiko, Tanaka, Naoki

ENGINEERING 7(12) 1797-1805 2021年12月
Pemafibrate protects against fatty acid-induced nephropathy by maintaining renal fatty acid metabolism.

1. Aomura D, Harada M, Yamada Y, Nakajima T, Hashimoto K, Tanaka N, Kamijo Y.

Metabolites 11(6) 372-372 2021年6月
Gallbladder cancer with ascites in a child with metachromatic leukodystrophy.

Koshu K, Ikeda T, Tamura D, Muramatsu K, Osaka H, Ono S, Adachi K, Nanba E, Nakajima T, Yamagata T.

Brain Dev 43(1) 140-143 2021年1月
Polyunsaturated fatty acid deficiency affects sulfatides and other sulfated glycans in lysosomes through autophagy-mediated degradation.

Wang Y, Nakajima T, Diao P, Yamada Y, Nakamura K, Nakayama J, Tanaka N, Aoyama T, Kamijo Y.

FASEB J 34(7) 9594-9614 2020年7月
A trans-fatty acid-rich diet promotes liver tumorigenesis in HCV core gene transgenic mice.

Hu X, Wang X, Jia F, Tanaka N, Kimura T, Nakajima T, Sato Y, Moriya K, Koike K, Gonzalez FJ, Nakayama J, Aoyama T.

Carcinogenesis 41(2) 159-170 2020年4月
PPARs as Metabolic Regulators in the Liver: Lessons from Liver-Specific PPAR-Null Mice.

Wang Y, Nakajima T, Gonzalez FJ, Tanaka N.

Int J Mol Sci. 21 2061 2020年3月
Effects of hypertension and antihypertensive treatments on sulfatide levels in serum and its metabolism

Guo, Ran, Hu, Xiao, Yamada, Yosuke, Harada, Makoto, Nakajima, Takero, Kashihara, Toshihide, Yamada, Mitsuhiko, Aoyama, Toshifumi, Kamijo, Yuji

HYPERTENSION RESEARCH 42(5) 598-609 2019年5月
Impact of chronic kidney dysfunction on serum Sulfatides and its metabolic pathway in mice

Yamada, Yosuke, Harada, Makoto, Hashimoto, Koji, Guo, Ran, Nakajima, Takero, Kashihara, Toshihide, Yamada, Mitsuhiko, Aoyama, Toshifumi, Kamijo, Yuji

GLYCOCONJUGATE JOURNAL 36(1) 1-11 2019年2月
Peroxisome proliferator-activated receptor attenuates high-cholesterol diet-induced toxicity and pro-thrombotic effects in mice

Lu, Yu, Harada, Makoto, Kamijo, Yuji, Nakajima, Takero, Tanaka, Naoki, Sugiyama, Eiko, Kyogashima, Mamoru, Gonzalez, Frank J, Aoyama, Toshifumi

ARCHIVES OF TOXICOLOGY 93(1) 149-161 2019年1月
PPARα protects against trans-fatty-acid-containing diet-induced steatohepatitis.

Hu X, Tanaka N, Guo R, Lu Y, Nakajima T, Gonzalez FJ, Aoyama T

J Nutr Biochem 39 77-85 2017年
Decreased fatty acid β-oxidation is the main cause of fatty liver induced by polyunsaturated fatty acid deficiency in mice.

Nakajima T, Yang Y, Lu Y, Kamijo Y, Yamada Y, Nakamura K, Koyama M, Yamaguchi S, Sugiyama E, Tanaka N …

Tohoku J Exp Med 242(3) 229-239 2017年
Fermentation-induced changes in the concentrations of organic acids, amino acids, sugars, and minerals and superoxide dismutase-like activity in tomato vinegar.

Koyama M, Ogasawara Y, Endou K, Akano H, Nakajima T, Aoyama T, Nakamura K.

Int. J. Food Prop. 20(4) 888-898 2017年査読有り
Characterization of bioactive agents in five types of marketed sprouts and comparison of their antihypertensive, antihyperlipidemic, and antidiabetic effects in fructose-loaded SHRs.

Nakamura K, Koyama M, Ishida R, Kitahara T, Nakajima T, Aoyama T

J Food Sci Technol 53(1) 581-590 2016年1月
Age-dependent PPARα activation induces hepatic sulfatide accumulation in transgenic mice carrying the hepatitis C virus core gene.

Tian Y, Yang Y, Zhang X, Nakajima T, Tanaka N, Sugiyama E, Kamijo Y, Lu Y, Moriya K, Koike K …

Glycoconj J 33(6) 927-936 2016年
Peroxisome proliferator-activated receptor α-dependent renoprotection of murine kidney by irbesartan.

Harada M, Kamijo Y, Nakajima T, Hashimoto K, Yamada Y, Shimojo H, Gonzalez FJ, Aoyama T

Clin Sci 130(21) 1969-1981 2016年

もっとみる

書籍等出版物

疾患モデルの作製と利用－脂質代謝異常と関連疾患＜上巻＞，第1章転写因子，第5節PPARα

中嶌岳郎,上條祐司,田中直樹,青山俊文 (担当:共著)

株式会社エル・アイ・シー 2015年1月31日

中嶌岳郎

基本情報

研究キーワード

研究分野

経歴

学歴

論文

書籍等出版物

所属学協会

共同研究・競争的資金等の研究課題

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