論文

国際誌
2021年4月16日

SARS-CoV-2 seroprevalence in healthcare workers at a frontline hospital in Tokyo.

Scientific reports
  • Hiroshi Fukuda
  • Kuniaki Seyama
  • Kanami Ito
  • Tomohiko Ai
  • Shuko Nojiri
  • Satoshi Hori
  • Mitsuru Wakita
  • Kaori Saito
  • Yuka Shida
  • Rie Nagura
  • Mayu Hasegawa
  • Chiaki Kanemoto
  • Mayumi Tokuhara
  • Katsunobu Okajima
  • Yukio Yoshikawa
  • Narimasa Katsuta
  • Takamasa Yamamoto
  • Mayumi Idei
  • Yuki Horiuchi
  • Kotoko Yamatani
  • Shigeki Misawa
  • Toshio Naito
  • Takashi Miida
  • Hiroyuki Sato
  • Nobutaka Hattori
  • Yoko Tabe
  • Kazuhisa Takahashi
  • 全て表示

11
1
開始ページ
8380
終了ページ
8380
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1038/s41598-021-87688-9

Healthcare workers (HCWs) are highly exposed to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The actual coronavirus disease (COVID-19) situation, especially in regions that are less affected, has not yet been determined. This study aimed to assess the seroprevalence of SARS-CoV-2 in HCWs working in a frontline hospital in Tokyo, Japan. In this cross-sectional observational study, screening was performed on consented HCWs, including medical, nursing, and other workers, as part of a mandatory health checkup. The screening test results and clinical characteristics of the participants were recorded. The antibody seroprevalence rate among the 4147 participants screened between July 6 and August 21, 2020, was 0.34% (14/4147). There was no significant difference in the seroprevalence rate between frontline HCWs with a high exposure risk and HCWs working in other settings with a low exposure risk. Of those seropositive for SARS-CoV-2, 64% (9/14) were not aware of any symptoms and had not previously been diagnosed with COVID-19. In conclusion, this study provides insights into the extent of infection and immune status in HCWs in Japan, which has a relatively low prevalence of COVID-19. Our findings aid in formulating public health policies to control virus spread in regions with low-intensity COVID-19.

リンク情報
DOI
https://doi.org/10.1038/s41598-021-87688-9
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/33863960
PubMed Central
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8052331
ID情報
  • DOI : 10.1038/s41598-021-87688-9
  • PubMed ID : 33863960
  • PubMed Central 記事ID : PMC8052331

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