Hiroaki Hirata

Volume-regulated anion channels conduct ATP in undifferentiated mammary cells and promote tumorigenesis in xenograft nude mouse

Kishio Furuya, Hiroaki Hirata, Takeshi Kobayashi, Hiroshi Ishiguro, Masahiro Sokabe

Frontiers in Cell and Developmental Biology, 12 1519642-1519642, Jan 15, 2025 Peer-reviewed

Bioinformatic Analysis of Actin-Binding Proteins in the Nucleolus During Heat Shock

Shinya Taniguchi, Takeru Torii, Toshiyuki Goto, Kohei Takeuchi, Rine Katsumi, Mako Sumida, Sunmin Lee, Sugimoto Wataru, Masaya Gessho, Katsuhiko Itoh …

Genes, 15(12) 1580-1580, Dec 9, 2024 Peer-reviewed

From stress fiber to focal adhesion: a role of actin crosslinkers in force transmission

Hiroki Katsuta, Masahiro Sokabe, Hiroaki Hirata

Frontiers in Cell and Developmental Biology, 12 1444827-1444827, Aug 13, 2024 Peer-reviewedCorresponding author

Loss of p53 function promotes DNA damage-induced formation of nuclear actin filaments.

Takeru Torii, Wataru Sugimoto, Katsuhiko Itoh, Natsuki Kinoshita, Masaya Gessho, Toshiyuki Goto, Ikuno Uehara, Wataru Nakajima, Yemima Budirahardja, Daisuke Miyoshi …

Cell Death & Disease, 14(11) 766-766, Nov 25, 2023 Peer-reviewedCorresponding author

Actin crosslinking by α-actinin averts viscous dissipation of myosin force transmission in stress fibers

Hiroki Katsuta, Satoru Okuda, Kazuaki Nagayama, Hiroaki Machiyama, Satoru Kidoaki, Masashi Kato, Masahiro Sokabe, Takaki Miyata, Hiroaki Hirata

iScience, 26(3) 106090-106090, Mar, 2023 Peer-reviewedCorresponding author

Anti-Malignant Effect of Tensile Loading to Adherens Junctions in Cutaneous Squamous Cell Carcinoma Cells

Oleg Dobrokhotov, Masaki Sunagawa, Takeru Torii, Shinji Mii, Keiko Kawauchi, Atsushi Enomoto, Masahiro Sokabe, Hiroaki Hirata

Frontiers in Cell and Developmental Biology, 9 728383-728383, Nov 11, 2021 Peer-reviewedCorresponding author

Sphingosine-1-Phosphate Induces ATP Release via Volume-Regulated Anion Channels in Breast Cell Lines

Kishio Furuya, Hiroaki Hirata, Takeshi Kobayashi, Masahiro Sokabe

Life, 11(8) 851-851, Aug 19, 2021 Peer-reviewed

Coordination between Cell Motility and Cell Cycle Progression in Keratinocyte Sheets via Cell-Cell Adhesion and Rac1

Hiroaki Hirata, Oleg Dobrokhotov, Masahiro Sokabe

iScience, 23(11) 101729-101729, Nov, 2020 Peer-reviewedCorresponding author

MMP24 as a Target of YAP Is a Potential Prognostic Factor in Cancer Patients

Wataru Sugimoto, Katsuhiko Itoh, Hiroaki Hirata, Yoshinori Abe, Takeru Torii, Yasumasa Mitsui, Yemima Budirahardja, Nobuyuki Tanaka, Keiko Kawauchi

Bioengineering, 7(1) 18-18, Feb 20, 2020 Peer-reviewed

Mechanical regulation of bone homeostasis through p130Cas-mediated alleviation of NF-κB activity

T. Miyazaki, Z. Zhao, Y. Ichihara, D. Yoshino, T. Imamura, K. Sawada, S. Hayano, H. Kamioka, S. Mori, H. Hirata …

Science Advances, 5(9) eaau7802-eaau7802, Sep, 2019 Peer-reviewed

DMPK is a New Candidate Mediator of Tumor Suppressor p53-Dependent Cell Death

Katsuhiko Itoh, Takahiro Ebata, Hiroaki Hirata, Takeru Torii, Wataru Sugimoto, Keigo Onodera, Wataru Nakajima, Ikuno Uehara, Daisuke Okuzaki, Shota Yamauchi …

Molecules, 24(17) 3175, Sep 1, 2019 Peer-reviewed

Planar compression of extracellular substrates induces S phase arrest via ATM-independent CHK2 activation

Kimihide Hayakawa, Hiroaki Hirata, Mikhail Samsonov, Masahiro Sokabe

Biochemical and Biophysical Research Communications, Nov, 2018 Peer-reviewed

Dopamine and Serotonin Receptors Cooperatively Modulate Pacemaker Activity of Intestinal Cells of Cajal.

Liu HN, Hirata H, Okuno Y, Okabe M, Furukawa K

The Chinese journal of physiology, 61(5) 302-312, Oct, 2018 Peer-reviewed

Tensile Loads on Tethered Actin Filaments Induce Accumulation of Cell Adhesion-Associated Proteins in Vitro

Daisuke Kiyoshima, Hitoshi Tatsumi, Hiroaki Hirata, Masahiro Sokabe

Langmuir, Sep, 2018 Peer-reviewedCorresponding author

Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms

Oleg Dobrokhotov, Mikhail Samsonov, Masahiro Sokabe, Hiroaki Hirata

Clinical and Translational Medicine, 7(1), Aug, 2018 Peer-reviewedCorresponding author

Substrate rigidity-dependent positive feedback regulation between YAP and ROCK2

Wataru Sugimoto, Katsuhiko Itoh, Yasumasa Mitsui, Takahiro Ebata, Hideaki Fujita, Hiroaki Hirata, Keiko Kawauchi

Cell Adhesion and Migration, 12(2) 101-108, Mar 4, 2018 Peer-reviewed

Actomyosin contractility provokes contact inhibition in E-cadherin-ligated keratinocytes

Hiroaki Hirata, Mikhail Samsonov, Masahiro Sokabe

Scientific Reports, 7, Apr 13, 2017 Peer-reviewedCorresponding author

Substrate Stiffness Influences Doxorubicin-Induced p53 Activation via ROCK2 Expression

Takahiro Ebata, Yasumasa Mitsui, Wataru Sugimoto, Miho Maeda, Keigo Araki, Hiroaki Machiyama, Ichiro Harada, Yasuhiro Sawada, Hideaki Fujita, Hiroaki Hirata …

BioMed Research International, 2017, 2017 Peer-reviewed

Association between tensin 1 and p130Cas at focal adhesions links actin inward flux to cell migration

Zhihai Zhao, Song Hui Tan, Hiroaki Machiyama, Keiko Kawauchi, Keigo Araki, Hiroaki Hirata, Yasuhiro Sawada

Biology Open, 5(4) 499-506, Apr 15, 2016 Peer-reviewed

Functions of the Tumor Suppressors p53 and Rb in Actin Cytoskeleton Remodeling

Takahiro Ebata, Hiroaki Hirata, Keiko Kawauchi

BioMed Research International, 2016, 2016 Peer-reviewed

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