Yukiko Matsuda

Profile Information

Affiliation: Research Scientist, Department of Molecular Biosciences, Radiation Effects Research Foundation
: Visiting Associate Professor, Research Institute for Radiation Biology and Medicine, Hiroshima University

Degree: 博士（医学)(大阪大学)

J-GLOBAL ID: 201801008798175989
researchmap Member ID: B000346555

Research Interests

ゲノム科学神経変性疾患

Research Areas

Research History

Apr, 2021 - Present

Visiting Associate Professor, Research Institute for Radiation Biology and Medicine, Hiroshima University
Nov, 2019 - Present

Research Scientist, Department of Molecular Biosciences (Concurrently assigned to the Biosample Research Center), Radiation Effects Research Foundation
Apr, 2019 - Mar, 2021

Researcher, Research Institute for Radiation Biology and Medicine, Hiroshima University
Apr, 2016 - Mar, 2019

Research Fellow, Japan Society for the Promotion of Science, Research Institute for Radiation Biology and Medicine, Hiroshima University
Apr, 2015 - Mar, 2016

Researcher, Research Institute for Radiation Biology and Medicine, Hiroshima University
Apr, 2014 - Mar, 2015

Research Associate, Research Institute for Radiation Biology and Medicine, Hiroshima University

Major Papers

Spectra and characteristics of somatic mutations induced by ionizing radiation in hematopoietic stem cells

Yukiko Matsuda, Arikuni Uchimura, Yasunari Satoh, Naohiro Kato, Masaaki Toshishige, Junko Kajimura, Kanya Hamasaki, Kengo Yoshida, Tomonori Hayashi, Asao Noda …

Proceedings of the National Academy of Sciences, 120(15), Apr 5, 2023 Peer-reviewedLead authorCorresponding author
Biallelic mutation of HSD17B4 induces middle age-onset spinocerebellar ataxia.

Yukiko Matsuda, Hiroyuki Morino, Ryosuke Miyamoto, Takashi Kurashige, Kodai Kume, Noriyoshi Mizuno, Yuhei Kanaya, Yui Tada, Ryosuke Ohsawa, Kazunori Yokota …

Neurology. Genetics, 6(1) e396, Feb, 2020 Peer-reviewedLead author
A mutation in the low voltage-gated calcium channel CACNA1G alters the physiological properties of the channel, causing spinocerebellar ataxia

Hiroyuki Morino, Yukiko Matsuda, Keiko Muguruma, Ryosuke Miyamoto, Ryosuke Ohsawa, Toshiyuki Ohtake, Reiko Otobe, Masahiko Watanabe, Hirofumi Maruyama, Kouichi Hashimoto …

MOLECULAR BRAIN, 8 89, Dec, 2015 Peer-reviewed
Mutations in Twinkle primase-helicase cause Perrault syndrome with neurologic features

Hiroyuki Morino, Sarah B. Pierce, Yukiko Matsuda, Tom Walsh, Ryosuke Ohsawa, Marta Newby, Keiko Hiraki-Kamon, Masahito Kuramochi, Ming K. Lee, Rachel E. Klevit …

NEUROLOGY, 83(22) 2054-2061, Nov, 2014 Peer-reviewed
BRI3 Inhibits Amyloid Precursor Protein Processing in a Mechanistically Distinct Manner from Its Homologue Dementia Gene BRI2

Shuji Matsuda, Yukiko Matsuda, Luciano D'Adamio

JOURNAL OF BIOLOGICAL CHEMISTRY, 284(23) 15815-15825, Jun, 2009 Peer-reviewed
BRI2 inhibits amyloid beta-peptide precursor protein processing by interfering with the docking of secretases to the substrate

Shuji Matsuda, Luca Giliberto, Yukiko Matsuda, Eileen M. McGowan, Luciano D'Adamio

JOURNAL OF NEUROSCIENCE, 28(35) 8668-8676, Aug, 2008 Peer-reviewed

Misc.

ゲノム編集技術が切り拓く神経内科学 CRISPR/Cas9を用いたSCA42モデルマウスの作製と解析

森野豊之, 松田由喜子, 倉重毅志, 川上秀史

臨床神経学, 59(Suppl.) S81-S81, Nov, 2019
SCAR8の原因遺伝子SYNE1のC末側変異と運動ニューロン疾患の関連

森野豊之, 久米広大, 小牟禮修, 松田由喜子, 倉重毅志, 川上秀史

日本人類遺伝学会大会プログラム・抄録集, 64th, 2019
SCA42の臨床と分子病態機序

森野豊之, 松田由喜子, 倉重毅志, 六車恵子, 外丸祐介, 橋本浩一, 丸山博文, 川上秀史

神経治療学(Web), 34(6) S111(J‐STAGE), 2017
SCA42の臨床と分子病態機序

森野豊之, 松田由喜子, 倉重毅志, 六車恵子, 外丸祐介, 橋本浩一, 丸山博文, 川上秀史

神経治療, 34(6) S111-S111, 2017
TDP‐17の原因遺伝子MAPTの新規挿入変異の同定と生化学解析

KAWAKAMI HIDESHI, MORINO TOYOYUKI, MATSUDA YUKIKO, OSAWA RYOSUKE, HIRAKI KEIKO, KURASHIGE TSUYOSHI, IZUMI YUISHIN, YAMASAKI YU, TAKAHASHI TETSUYA, TAKASHIMA AKIHIKO …

日本生物学的精神医学会誌, 266, 2014

Research Projects

Whole-genome sequence analysis of radiation-induced mutations in human hematopoietic stem cells

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C), Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2022 - Mar, 2025

Osamu Tanabe, Yukiko Matsuda, Arikuni Uchimura, Kengo Yoshida
Study on Protective Effects of NRF2, an Anti-oxidative Stress Transcription Factor, against Radiation-induced Oncogenesis and Mutagenesis

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C), Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2020 - Mar, 2022

Osamu Tanabe, Yukiko Matsuda, Noriaki Yoshida
A new oligonucleotide treatment with CRISPR/Cas13 using model mice of spinocerebellar ataxia.

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C), Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2019 - Mar, 2022

Yukiko Matsuda
Analysis of pathological mechanism of spinocerebellar ataxia using differentiated cerebellar cells derived from iPS cells and model mouse.

Grants-in-Aid for Scientific Research Grant-in-Aid for JSPS Fellows, Grant-in-Aid for JSPS Fellows, Japan Society for the Promotion of Science, Apr, 2016 - Mar, 2019

Yukiko Matsuda
The mechanism of neuronal cell death induced by a new mutation of peroxisomal enzyme via the mitochondorial disfunction

Grants-in-Aid for Scientific Research Grant-in-Aid for Research Activity Start-up, Grant-in-Aid for Research Activity Start-up, Japan Society for the Promotion of Science, Aug, 2014 - Mar, 2016

Yukiko Matsuda

Profile Information

Research Interests

Research Areas

Research History

Major Papers

Misc.

Research Projects

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