2016年3月
Induction of protein crystallization by platinum nanoparticles
CHEMICAL PHYSICS LETTERS
- ,
- 巻
- 647
- 号
- 開始ページ
- 181
- 終了ページ
- 184
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1016/j.cplett.2015.12.070
- 出版者・発行元
- ELSEVIER SCIENCE BV
We have investigated effects of platinum nanoparticles (PtNPs) on protein crystal nucleation. The presence of PtNPs increased the number of crystals in a crystallization solution, indicating that the PtNPs have the ability to promote the crystal nucleation. Dynamic light scattering measurements revealed that the PtNP gathers more than 10 lysozyme molecules around it to form an embryonic complex of PtNP and lysozyme. Zeta potential measurements revealed that the charges of the lysozyme molecules were reduced by delocalization of their charges in the complex. As a result, the energy barrier of association between the complexes is reduced, followed by the nucleation. (C) 2016 Elsevier B.V. All rights reserved.
- リンク情報
-
- DOI
- https://doi.org/10.1016/j.cplett.2015.12.070
- Web of Science
- https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000371401500035&DestApp=WOS_CPL
- URL
- https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84957555520&origin=inward
- ID情報
-
- DOI : 10.1016/j.cplett.2015.12.070
- ISSN : 0009-2614
- eISSN : 1873-4448
- SCOPUS ID : 84957555520
- Web of Science ID : WOS:000371401500035