徐明利 (Mingli Xu) - マイポータル

基本情報

所属: 昭和大学；東京医科大学藤が丘リハビリテーション病院リハビリテーション科；東京医科大学医学部助教；客員講師

研究者番号: 80597964
J-GLOBAL ID: 202001012418564576
researchmap会員ID: R000009843

論文

Intradermal Injection of A Protein Alone Without Additional Adjuvants Using A Needle-Free Pyro-Drive Jet Injector Induces Potent CD8+ T Cell-Mediated Antitumor Immunity

Jukito Sonoda, Izuru Mizoguchi, Natsuki Yamaguchi, Eri Horio, Satomi, Miyakawa, Mingli Xu, Toshihiko Yoneto, Yasuhiro Katahira, Hideaki Hasegawa …

International Journal of Molecular Sciences 2025年5月査読有り
Multicenter International Study of the Consensus Immunoscore for the Prediction of Relapse and Survival in Early-Stage Colon Cancer.

Bernhard Mlecnik, Alessandro Lugli, Gabriela Bindea, Florence Marliot, Carlo Bifulco, Jiun-Kae Jack Lee, Inti Zlobec, Tilman T Rau, Martin D Berger, Iris D Nagtegaal …

Cancers 15(2) 2023年1月8日
Clinical Performance of the Consensus Immunoscore in Colon Cancer in the Asian Population from the Multicenter International SITC Study

Bernhard Mlecnik, Toshihiko Torigoe, Gabriela Bindea, Boryana Popivanova, Mingli Xu, Tomonobu Fujita, Shoichi Hazama, Nobuaki Suzuki, Hiroaki Nagano, Kiyotaka Okuno …

Cancers 14(18) 4346-4365 2022年9月査読有り
Author Correction: IL-23p19 and CD5 antigen-like form a possible novel heterodimeric cytokine and contribute to experimental autoimmune encephalomyelitis development.

Hideaki Hasegawa, Izuru Mizoguchi, Naoko Orii, Shinya Inoue, Yasuhiro Katahira, Toshihiko Yoneto, Mingli Xu, Toru Miyazaki, Takayuki Yoshimoto

Scientific reports 11(1) 21958-21958 2021年11月3日
IL-23p19 and CD5 antigen-like form a possible novel heterodimeric cytokine and contribute to experimental autoimmune encephalomyelitis development.

Hideaki Hasegawa, Izuru Mizoguchi, Naoko Orii, Shinya Inoue, Yasuhiro Katahira, Toshihiko Yoneto, Mingli Xu, Toru Miyazaki, Takayuki Yoshimoto

Scientific reports 11(1) 5266-5266 2021年3月4日
Multicenter International Society for Immunotherapy of Cancer Study of the Consensus Immunoscore for the Prediction of Survival and Response to Chemotherapy in Stage III Colon Cancer.

Bernhard Mlecnik, Carlo Bifulco, Gabriela Bindea, Florence Marliot, Alessandro Lugli, J Jack Lee, Inti Zlobec, Tilman T Rau, Martin D Berger, Iris D Nagtegaal …

Journal of clinical oncology : official journal of the American Society of Clinical Oncology 38(31) JCO1903205-3651 2020年9月8日査読有り
EBV-induced gene 3 augments IL-23Rα protein expression through a chaperone calnexin.

Izuru Mizoguchi, Mio Ohashi, Hideaki Hasegawa, Yukino Chiba, Naoko Orii, Shinya Inoue, Chiaki Kawana, Mingli Xu, Katsuko Sudo, Koji Fujita …

The Journal of clinical investigation 130(11) 6124-6140 2020年8月18日査読有り
International validation of the consensus Immunoscore for the classification of colon cancer: a prognostic and accuracy study.

Franck Pagès, Bernhard Mlecnik, Florence Marliot, Gabriela Bindea, Fang-Shu Ou, Carlo Bifulco, Alessandro Lugli, Inti Zlobec, Tilman T Rau, Martin D Berger …

Lancet (London, England) 391(10135) 2128-2139 2018年5月26日査読有り
Regulation of myelopoiesis by proinflammatory cytokines in infectious diseases.

Yukino Chiba, Izuru Mizoguchi, Hideaki Hasegawa, Mio Ohashi, Naoko Orii, Taro Nagai, Miyaka Sugahara, Yasunori Miyamoto, Mingli Xu, Toshiyuki Owaki …

Cellular and molecular life sciences : CMLS 75(8) 1363-1376 2018年4月査読有り
Interleukin-27 Exerts Its Antitumor Effects by Promoting Differentiation of Hematopoietic Stem Cells to M1 Macrophages.

Yukino Chiba, Izuru Mizoguchi, Junichi Furusawa, Hideaki Hasegawa, Mio Ohashi, Mingli Xu, Toshiyuki Owaki, Takayuki Yoshimoto

Cancer research 78(1) 182-194 2018年1月1日査読有り
Protective effects against tumors and infection by interleukin-27 through promotion of expansion and differentiation of hematopoietic stem cells into myeloid progenitors.

Naoko Orii, Izuru Mizoguchi, Yukino Chiba, Hideaki Hasegawa, Mio Ohashi, Mingli Xu, Taro Nagai, Nakaba Ochiai, Yuki Mochizuki, Toshiyuki Owaki …

Oncoimmunology 7(5) e1421892 2018年査読有り
Prediction of Chemical Respiratory and Contact Sensitizers by OX40L Expression in Dendritic Cells Using a Novel 3D Coculture System.

Izuru Mizoguchi, Mio Ohashi, Yukino Chiba, Hideaki Hasegawa, Mingli Xu, Toshiyuki Owaki, Takayuki Yoshimoto

Frontiers in immunology 8 929-929 2017年査読有り
Expanding Diversity in Molecular Structures and Functions of the IL-6/IL-12 Heterodimeric Cytokine Family.

Hideaki Hasegawa, Izuru Mizoguchi, Yukino Chiba, Mio Ohashi, Mingli Xu, Takayuki Yoshimoto

Frontiers in immunology 7 479-479 2016年査読有り
Therapeutic potential of interleukin-27 against cancers in preclinical mouse models.

Izuru Mizoguchi, Yukino Chiba, Jun-Ichi Furusawa, Mingli Xu, Ren Tsunoda, Kaname Higuchi, Takayuki Yoshimoto

Oncoimmunology 4(10) e1042200 2015年10月査読有り
Potential clinical application of interleukin-27 as an antitumor agent.

Takayuki Yoshimoto, Yukino Chiba, Jun-Ichi Furusawa, Mingli Xu, Ren Tsunoda, Kaname Higuchi, Izuru Mizoguchi

Cancer science 106(9) 1103-10 2015年9月査読有り
Pivotal roles of T-helper 17-related cytokines, IL-17, IL-22, and IL-23, in inflammatory diseases.

Ning Qu, Mingli Xu, Izuru Mizoguchi, Jun-ichi Furusawa, Kotaro Kaneko, Kazunori Watanabe, Junichiro Mizuguchi, Masahiro Itoh, Yutaka Kawakami, Takayuki Yoshimoto

Clinical & developmental immunology 2013 968549-968549 2013年査読有り
Retention ability and CTL inducibility of DC vaccine administrated into lymph nodes

Yuji Ota, Mingli Xu, Izuru Mizoguchi, Masakatsu Takanashi, Katsuko Sudo, Masahiko Kuroda, Takayuki Yoshimoto, Kazuhiko Kasuya, Akihiko Tsuchida, Sakae Unezaki

Journal of Tokyo Medical University 70(4) 444-449 2012年10月査読有り
能動免疫療法における免疫誘導・抗腫瘍効果を規定するバイオマーカーの検索

川瀬芳恵, 藤田知信, 大泉梓, 野路しのぶ, 桜井敏晴, 南雲春菜, 徐明利, 中山睿一, 垣見和宏, 鳥越俊彦 …

日本がん免疫学会総会プログラム・抄録集 16回 97-97 2012年7月
Identification of a novel role of Septin 10 in paclitaxel-resistance in cancers through a functional genomics screen.

Mingli Xu, Masakatsu Takanashi, Kosuke Oikawa, Hirotaka Nishi, Keiichi Isaka, Takayuki Yoshimoto, Junko Ohyashiki, Masahiko Kuroda

Cancer science 103(4) 821-7 2012年4月査読有り
Regulation of the development of acute hepatitis by IL-23 through IL-22 and IL-17 production.

Mingli Xu, Noriko Morishima, Izuru Mizoguchi, Yukino Chiba, Koji Fujita, Masahiko Kuroda, Yoichiro Iwakura, Daniel J Cua, Koji Yasutomo, Junichiro Mizuguchi …

European journal of immunology 41(10) 2828-39 2011年10月査読有り

もっとみる

MISC

A Novel Role for Epstein-Barr Virus-Induced Gene 3 as An Intracellular Molecule That Enhances IL-23 Receptor Expression by Binding to Calnexin and IL-23 Receptor

Izuru Mizoguchi, Yukino Chiba, Hideaki Hasegawa, Mio Ohashi, Mingli Xu, Toshiyuki Owaki, Takayuki Yoshimoto

CYTOKINE 100 48-49 2017年12月
IL-23によるIL-22とIL-17産生を介した急性肝炎発症の調節

Mingli Xu, Noriko Morishima, Izuru Mizoguchi, Yukino Chiba, Takayuki Yoshimoto, Junichiro Mizuguchi, Koji Fujita, Masahiko Kuroda, Yoichiro Iwakura, Daniel J Cua …

東京医科大学雑誌 70(1) 98-98 2012年1月30日
Regulation of inflammatory immune responses leading to the development of bone destructive autoimmune disease rheumatoid arthritis by IL-27

Takayuki Yoshimoto, Mingli Xu, Izuru Mizuguchi, Yukino Chiba, Sadahiro Kamiya, Masanori Matsui, Shiva Shahrara, Junichiro Mizuguchi

ARTHRITIS RESEARCH & THERAPY 14 2012年
A functional genomic screen identifies a role of USP15 and Septin 10 in spindle-checkpoint and Paclitaxel-resistance in human cancers

Mingli Xu, Masakatsu Takanashi, Kosuke Oikawa, Masami Tanaka, Hirotaka Nishi, Keiichi Isaka, Motoshige Kudo, Masahiko Kuroda

CANCER RESEARCH 69 2009年5月
Expression of G-protein-coupled receptor kinase 4 is associated with breast cancer tumorigenesis

Jun Matsubayashi, Masakatsu Takanashi, Kosuke Oikawa, Mingli Xu, Kiyoshi Mukai, Masahiko Kuroda

MOLECULAR CANCER THERAPEUTICS 6(12) 3501S-3501S 2007年12月

共同研究・競争的資金等の研究課題

脳卒中・脊髄損傷の後遺障害のリハビリテーション治療への漢方薬の応用

日本学術振興会科学研究費助成事業基盤研究(C) 2021年4月 - 2024年3月

徐明利, 曲寧, 隅山香織, 善本隆之
IL-12関連サイトカインIL-27によるがん治療の臨床応用を目指した包括的研究

日本学術振興会科学研究費助成事業基盤研究(C) 2018年4月 - 2021年3月

徐明利, 善本隆之
新しいIL-6/IL-12ファミリーサイトカインの同定とその機能解析

日本学術振興会科学研究費助成事業基盤研究(C) 2015年4月 - 2018年3月

徐明利, 善本隆之
ＩＬ－２３によるＮｏｔｃｈシグナルを介した新しい免疫制御機構

日本学術振興会科学研究費助成事業基盤研究(C) 2011年 - 2013年

徐明利, 善本隆之, 須藤カツ子