Yoshihiro Hirade - My portal

Profile Information

Affiliation: Graduate School of Pharmaceutical Sciences, Osaka University

Degree: Ph.D.(Osaka University)

Researcher number: 80795526
ORCID ID: https://orcid.org/0000-0003-3270-7679
Researcher ID: L-9860-2015
researchmap Member ID: R000024128

Papers

A novel application of hectorite nanoclay for preparation of colorectal cancer spheroids with malignant potential

Yoshihiro Hirade, Munehiro Kubota, Kaori Kitae, Harumi Yamamoto, Hiroko Omori, Susumu Shinoki, Takao Ohmura, Kazutake Tsujikawa

LAB ON A CHIP, 23(4) 609-623, Jan, 2023 Peer-reviewedLead author
Discovery of two novel ALKBH5 selective inhibitors that exhibit uncompetitive or competitive type and suppress the growth activity of glioblastoma multiforme

Hikaru Takahashi, Hiroaki Hase, Takuya Yoshida, Junki Tashiro, Yoshihiro Hirade, Kaori Kitae, Kazutake Tsujikawa

CHEMICAL BIOLOGY & DRUG DESIGN, 100(1) 1-12, Jul, 2022 Peer-reviewed
Precise and efficient nucleotide substitution near genomic nick via noncanonical homology-directed repair

Kazuhiro Nakajima, Yue Zhou, Akiko Tomita, Yoshihiro Hirade, Channabasavaiah B. Gurumurthy, Shinichiro Nakada

GENOME RESEARCH, 28(2) 223-230, Feb, 2018 Peer-reviewed
Structural insights into two distinct binding modules for Lys63-linked polyubiquitin chains in RNF168

Tomio S. Takahashi, Yoshihiro Hirade, Aya Toma, Yusuke Sato, Atsushi Yamagata, Sakurako Goto-Ito, Akiko Tomita, Shinichiro Nakada, Shuya Fukai

NATURE COMMUNICATIONS, 9, Jan, 2018 Peer-reviewed
Identification and functional analysis of 2-hydroxyflavanone C-glucosyltransferase in soybean (Glycine max)

Yoshihiro Hirade, Naoyuki Kotoku, Kazuyoshi Terasaka, Yumiko Saijo-Hamano, Akemi Fukumoto, Hajime Mizukami

FEBS LETTERS, 589(15) 1778-1786, Jul, 2015 Peer-reviewedLead authorCorresponding author
Srs2 Plays a Critical Role in Reversible G(2) Arrest upon Chronic and Low Doses of UV Irradiation via Two Distinct Homologous Recombination-Dependent Mechanisms in Postreplication Repair-Deficient Cells

Takashi Hishida, Yoshihiro Hirade, Nami Haruta, Yoshino Kubota, Hiroshi Iwasaki

MOLECULAR AND CELLULAR BIOLOGY, 30(20) 4840-4850, Oct, 2010 Peer-reviewed

Misc.

膵癌におけるYAP/TAZ活性化シグナルの機能解析

高橋里佳, 上田裕子, 北惠郁緒里, 平出祥啓, 長谷拓明, 神宮司健太郎, 相原彩子, 西野泰斗, 辻川和丈

日本薬学会年会要旨集, 141年会 29V08-am07S, Mar, 2021
ゲノム恒常性維持機構の破綻と疾患発症の分子メカニズムニックによる正確で効率のよいゲノム編集法では非古典的なHDRが利用されている

中嶋一裕, 周越, 富田亜希子, 平出祥啓, 中田慎一郎

生命科学系学会合同年次大会, 2017年度 [3PW02-4], Dec, 2017

Research Projects

RNF168によるDNA２本鎖切断応答・修復制御機構の解明

科学研究費助成事業基盤研究(C), 日本学術振興会, Apr, 2017 - Mar, 2019

平出祥啓, 中田慎一郎