Shota Tanaka

Profile Information

Affiliation: Graduate School of Pharmaceutical Sciences, Osaka University

Researcher number: 80880294
J-GLOBAL ID: 202101012567073540
researchmap Member ID: R000029068

Papers

Upregulation of Robo4 expression by SMAD signaling suppresses vascular permeability and mortality in endotoxemia and COVID-19 models.

Maaya Morita, Aki Yoneda, Nagisa Tokunoh, Tatsumi Masaki, Keisuke Shirakura, Mayumi Kinoshita, Rina Hashimoto, Naoya Shigesada, Junya Takahashi, Masashi Tachibana, Shota Tanaka, Masanori Obana, Nobumasa Hino, Masahito Ikawa, Kazutake Tsujikawa, Chikako Ono, Yoshiharu Matsuura, Hiroyasu Kidoya, Nobuyuki Takakura, Yoshiaki Kubota, Takefumi Doi, Kazuo Takayama, Yasuo Yoshioka, Yasushi Fujio, Yoshiaki Okada

Proceedings of the National Academy of Sciences of the United States of America, 120(3) e2213317120, Jan 17, 2023
Upregulation of OASIS/CREB3L1 in podocytes contributes to the disturbance of kidney homeostasis

Yoshiaki Miyake, Masanori Obana, Ayaha Yamamoto, Shunsuke Noda, Koki Tanaka, Hibiki Sakai, Narihito Tatsumoto, Chihiro Makino, Soshi Kanemoto, Go Shioi, Shota Tanaka, Makiko Maeda, Yoshiaki Okada, Kazunori Imaizumi, Katsuhiko Asanuma, Yasushi Fujio

Communications Biology, 5(1), Dec, 2022 Peer-reviewed
Myeloid cell-specific ablation of Runx2 gene exacerbates post-infarct cardiac remodeling.

Masashi Tomimatsu, Kotaro Matsumoto, Moe Ashizuka, Shohei Kumagai, Shota Tanaka, Takafumi Nakae, Kosei Yokota, Shunsuke Kominami, Ryota Kajiura, Daisuke Okuzaki, Daisuke Motooka, Aki Shiraishi, Takaya Abe, Hideo Matsuda, Yoshiaki Okada, Makiko Maeda, Shigeto Seno, Masanori Obana, Yasushi Fujio

Scientific reports, 12(1) 16656-16656, Oct 5, 2022
SARS-CoV-2 disrupts respiratory vascular barriers by suppressing Claudin-5 expression.

Rina Hashimoto, Junya Takahashi, Keisuke Shirakura, Risa Funatsu, Kaori Kosugi, Sayaka Deguchi, Masaki Yamamoto, Yugo Tsunoda, Maaya Morita, Kosuke Muraoka, Masato Tanaka, Tomoaki Kanbara, Shota Tanaka, Shigeyuki Tamiya, Nagisa Tokunoh, Atsushi Kawai, Masahito Ikawa, Chikako Ono, Keisuke Tachibana, Masuo Kondoh, Masanori Obana, Yoshiharu Matsuura, Akihiro Ohsumi, Takeshi Noda, Takuya Yamamoto, Yasuo Yoshioka, Yu-Suke Torisawa, Hiroshi Date, Yasushi Fujio, Miki Nagao, Kazuo Takayama, Yoshiaki Okada

Science advances, 8(38) eabo6783, Sep 23, 2022 Peer-reviewed
CXCL10 is a novel anti-angiogenic factor downstream of p53 in cardiomyocytes.

Tri Wahyuni, Shota Tanaka, Ryuta Igarashi, Yoshiaki Miyake, Ayaha Yamamoto, Shota Mori, Yusuke Kametani, Masashi Tomimatsu, Shota Suzuki, Kosei Yokota, Yoshiaki Okada, Makiko Maeda, Masanori Obana, Yasushi Fujio

Physiological reports, 10(9) e15304, May, 2022 Peer-reviewed
Yes‐associated protein activation potentiates glycogen synthase kinase‐3 inhibitor‐induced proliferation of neonatal cardiomyocytes and iPS cell‐derived cardiomyocytes

Yusuke Kametani, Shota Tanaka, Yuriko Wada, Shota Suzuki, Ayaka Umeda, Kosuke Nishinaka, Yoshiaki Okada, Makiko Maeda, Shigeru Miyagawa, Yoshiki Sawa, Masanori Obana, Yasushi Fujio

Journal of Cellular Physiology, Mar 21, 2022 Peer-reviewed
Exhaustive exploration of novel factors related to cardiomyocyte proliferation using the cell cycle-sensitive protein FUCCI

Wada Yuriko, Kametani Yusuke, Suzuki Shota, Umeda Ayaka, Nishinaka Kosuke, Tanaka Shota, Maeda Makiko, Okada Yoshiaki, Obana Masanori, Fujio Yasushi

Proceedings for Annual Meeting of The Japanese Pharmacological Society, 95 2-O-099, 2022
Endogenous YAP activity potentiates GSK3 inhibitors-induced proliferation of cardiomyocytes.

Kametani Yusuke, Suzuki Shota, Umeda Ayaka, Nishinaka Kosuke, Tanaka Shota, Maeda Makiko, Okada Yoshiaki, Obana Masanori, Fujio Yasushi

Proceedings for Annual Meeting of The Japanese Pharmacological Society, 95 1-YIA-19, 2022
Increased OASIS in podocytes contributes to the disruption of kidney homeostasis

Miyake Yoshiaki, Obana Masanori, Yamamoto Ayaha, Tanaka Shota, Maeda Makiko, Okada Yoshiaki, Imaizumi Kazunori, Asanuma Katsuhiko, Fujio Yasushi

Proceedings for Annual Meeting of The Japanese Pharmacological Society, 95 1-YIA-23, 2022
IL-6 family cytokines, STAT3 activators, exhibit differential effects in a ligand-specific manner in podocytes

Sayuri Mitsuoka, Obana Masanori, Miyake Yoshiaki, Yamamoto Ayaha, Tanaka Shota, Maeda Makiko, Okada Yoshiaki, Fujio Yasushi

Proceedings for Annual Meeting of The Japanese Pharmacological Society, 95 1-O-010, 2022
TGFβ3 exacerbates myocardial remodeling after myocardial infarction.

Tomimatsu Masashi, Yokota Kosei, Kominami Shunsuke, Tanaka Shota, Maeda Makiko, Okada Yoshiaki, Obana Masanori, Fujio Yasushi

Proceedings for Annual Meeting of The Japanese Pharmacological Society, 95 1-O-036, 2022
Leupaxin is upregulated in fibrotic kidneys and contributes to the proliferation of kidney fibroblasts

Noda Shunsuke, Obana Masanori, Miyake Yoshiaki, Yamamoto Ayaha, Tanaka Shota, Maeda Makiko, Okada Yoshiaki, Fujio Yasushi

Proceedings for Annual Meeting of The Japanese Pharmacological Society, 95 2-O-071, 2022
Establishment of a novel method for analysis of biological functions of myeloid cell subpopulation in cardiovascular diseases using TRECK system.

Yokota Kosei, Tomimatsu Masashi, Kominami Shunsuke, Kajiura Ryota, Tanaka Shota, Obana Masanori, Okada Yoshiaki, Fujio Yasushi

Proceedings for Annual Meeting of The Japanese Pharmacological Society, 96 3-B-O09-3, 2022
Runx1 is upregulated by STAT3 and promotes cell proliferation in neonatal rat cardiomyocytes.

Shota Suzuki, Kametani Yusuke, Umeda Ayaka, Nishinaka Kosuke, Tanaka Shota, Obana Masanori, Okada Yoshiaki, Fujio Yasushi

Proceedings for Annual Meeting of The Japanese Pharmacological Society, 96 3-B-O09-1, 2022
PAI-1 induction is a critical event for the onset of lipopolysaccharide-induced acute kidney injury.

Koki Tanaka, Obana Masanori, Sakai Hibiki, Kamuro Hiroyasu, Yamamoto Ayaha, Tanaka Syota, Okada Yoshiaki, Fujio Yasushi

Proceedings for Annual Meeting of The Japanese Pharmacological Society, 96 1-B-P-046, 2022
PKNOX2 regulates myofibroblast functions and tubular cell survival during kidney fibrosis.

Yoshiaki Miyake, Masanori Obana, Takafumi Nakae, Ayaha Yamamoto, Shota Tanaka, Makiko Maeda, Yoshiaki Okada, Yasushi Fujio

Biochemical and biophysical research communications, 571 88-95, Sep 24, 2021 Peer-reviewed
Title: Gene transfer by pyro-drive jet injector is a novel therapeutic approach for muscle diseases.

Takafumi Nakae, Masanori Obana, Takahiro Maeda, Akari Ikeda, Hiroshi Miyazaki, Shota Tanaka, Makiko Maeda, Kunihiko Yamashita, Kazuhiro Terai, Satoshi Obika, Yasushi Fujio

Gene, 788 145664-145664, Jul 1, 2021 Peer-reviewed
Maresin-1 induces cardiomyocyte hypertrophy through IGF-1 paracrine pathway.

Tri Wahyuni, Arisa Kobayashi, Shota Tanaka, Yoshiaki Miyake, Ayaha Yamamoto, Anton Bahtiar, Shota Mori, Yusuke Kametani, Masashi Tomimatsu, Kotaro Matsumoto, Makiko Maeda, Masanori Obana, Yasushi Fujio

American journal of physiology. Cell physiology, 321(1) C82-C93, Jul 1, 2021 Peer-reviewed
ポドサイトの転写因子OASISは腎病態進展に寄与する

三宅芳明, 尾花理徳, 山本彩葉, 田中翔大, 前田真貴子, 今泉和則, 淺沼克彦, 藤尾慈

日本腎臓学会誌, 63(4) 499-499, Jun, 2021 Peer-reviewed
Transcription factor old astrocyte specifically induced substance is a novel regulator of kidney fibrosis.

Ayaha Yamamoto, Hitomi Morioki, Takafumi Nakae, Yoshiaki Miyake, Takeo Harada, Shunsuke Noda, Sayuri Mitsuoka, Kotaro Matsumoto, Masashi Tomimatsu, Soshi Kanemoto, Shota Tanaka, Makiko Maeda, Simon J Conway, Kazunori Imaizumi, Yasushi Fujio, Masanori Obana

FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 35(2) e21158, Feb, 2021 Peer-reviewed

Research Projects

心筋再生治療のための心筋細胞脱分化におけるマイトファジーの意義の解明

科学研究費助成事業研究活動スタート支援, 日本学術振興会, Sep, 2020 - Mar, 2022

田中翔大

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