飯島正富 (Masatomi Iijima) - マイポータル

基本情報

所属: 公益財団法人微生物化学研究会微生物化学研究所沼津支所上級研究員

学位: 博士（農学）(岐阜大学)

J-GLOBAL ID: 200901018322418676
researchmap会員ID: 1000146011

研究キーワード

研究分野

ライフサイエンス / 薬系化学、創薬科学 /

学歴

岐阜大学, 大学院連合農学研究科

論文

Qualitative differences in disease-associated MEK mutants reveal molecular signatures and aberrant signaling-crosstalk in cancer

Yuji Kubota, Yuko Fujioka, Ashwini Patil, Yusuke Takagi, Daisuke Matsubara, Masatomi Iijima, Isao Momose, Ryosuke Naka, Kenta Nakai, Nobuo N. Noda …

Nature Communications 13(1) 2022年査読有り
Metacytofilin has potent anti-malarial activity.

Arpron Leesombun, Masatomi Iijima, Baldorj Pagmadulam, Banzragchgarav Orkhon, Hiroyasu Doi, Kunio Issiki, Ryuichi Sawa, Coh-Ichi Nihei, Yoshifumi Nishikawa

Parasitology international 81 102267-102267 2020年12月8日
A new indole glycoside from Kitasatospora sp. MG372-hF19 carrying a 6-deoxy-α-L-talopyranose moiety.

Kohda Y, Sakamoto S, Otsuka Y, Sawa R, Kubota Y, Igarashi M, Muramatsu H, Iijima M, Kawada M

The Journal of antibiotics 2019年11月査読有り
Leucinostatin Y: A Peptaibiotic Produced by the Entomoparasitic Fungus Purpureocillium lilacinum 40-H-28.

Isao Momose, Takefumi Onodera, Hiroyasu Doi, Hayamitsu Adachi, Masatomi Iijima, Yohko Yamazaki, Ryuichi Sawa, Yumiko Kubota, Masayuki Igarashi, Manabu Kawada

Journal of natural products 82(5) 1120-1127 2019年5月24日
Correction to: Metacytofilin, a novel immunomodulator produced by Metarhizium sp. TA2759

飯島正富

J. Antibiot. 71 908-909 2018年査読有り
A guanine derivative as a new MEK inhibitor produced by Streptomyces sp. MK63-43F2

Masatomi Iijima, Yuji Kubota, Ryuichi Sawa, Yumiko Kubota, Masaki Hatano, Masayuki Igarashi, Manabu Kawada, Isao Momose, Mutsuhiro Takekawa, Masakatsu Shibasaki

Journal of Antibiotics 71(1) 135-138 2018年1月1日査読有り
Phenazine carboxylic acid and its derivative induce osteoblast differentiation in preosteoblastic MC3T3-E1 cells but adipocyte differentiation in pluripotent mesenchymal C3H10T1/2 cells

Shuichi Sakamoto, Takumi Watanabe, Yasuko Kohda, Masatomi Iijima, Ryuichi Sawa, Maiko Okada, Hayamitsu Adachi, Yoshio Nishimura, Manabu Kawada

JOURNAL OF ANTIBIOTICS 70(12) 1146-1149 2017年12月査読有り
Acremopeptin, a new peptaibol from Acremonium sp PF1450

Masatomi Iijima, Masahide Amemiya, Ryuichi Sawa, Yumiko Kubota, Takao Kunisada, Isao Momose, Manabu Kawadal, Masakatsu Shibasaki

JOURNAL OF ANTIBIOTICS 70(6) 791-794 2017年6月査読有り
Quinofuracins A-E, Produced by the Fungus Staphylotrichum boninense PF1444, Show p53-Dependent Growth Suppression

Daisuke Tatsuda, Isao Momose, Tetsuya Someno, Ryuichi Sawa, Yumiko Kubota, Masatomi Iijima, Takao Kunisada, Takumi Watanabe, Masakatsu Shibasaki, Akio Nomoto

JOURNAL OF NATURAL PRODUCTS 78(2) 188-195 2015年2月査読有り
Increased ABCB1 Expression in TP-110-Resistant RPMI-8226 Cells

Masatomi Iijima, Isao Momose, Daishiro Ikeda

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY 74(9) 1913-1919 2010年9月査読有り
TP-110, a New Proteasome Inhibitor, Down-regulates IAPs in Human Multiple Myeloma Cells

Masatomi Iijima, Isao Momose, Daishiro Ikeda

ANTICANCER RESEARCH 29(4) 977-985 2009年4月査読有り
A new proteasome inhibitor, TP-110, induces apoptosis in human prostate cancer PC-3 cells

Isao Momose, Masatomi Iijima, Manabu Kawada, Daishiro Ikeda

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY 71(4) 1036-1043 2007年4月査読有り
Augmentation of cellular immunity by kigamicin D

T Masuda, S Ohba, M Kawada, M Iijima, H Inoue, M Osono, D Ikeda, S Kunimoto

JOURNAL OF ANTIBIOTICS 59(4) 215-219 2006年4月査読有り
Biosynthesis of IC202C, a new siderophore with immunosuppressive activity

M Iijima, T Someno, M Amemiya, M Ishizuka, H Naganawa, T Takeuchi

JOURNAL OF ANTIBIOTICS 53(12) 1411-1415 2000年12月査読有り
IC202A, a new siderophore with immunosuppressive activity produced by Streptoalloteichus sp. 1454-19 I. Taxonomy, fermentation, isolation and biological activity

M Iijima, T Someno, C Imada, Y Okami, M Ishizuka, T Takeuchi

JOURNAL OF ANTIBIOTICS 52(1) 20-24 1999年1月査読有り
DETHYMICIN, A NOVEL IMMUNOSUPPRESSANT ISOLATED FROM AN AMYCOLATOPSIS - FERMENTATION, ISOLATION, PHYSICOCHEMICAL PROPERTIES AND BIOLOGICAL-ACTIVITIES

M UENO, M IIJIMA, T MASUDA, N KINOSHITA, H IINUMA, H NAGANAWA, M HAMADA, M ISHIZUKA, T TAKEUCHI

JOURNAL OF ANTIBIOTICS 45(12) 1819-1826 1992年12月査読有り
A low molecular weight immunomodulator, IC201 (1.3.-dihydroxy-8-decen-5-one) found in microbial products (II) immunomodulatory activity and protective effect against infection with pseudomonas aeruginosa in mice

H. Kumagai, M. Iijima, M. Osono, S. Mizutani, H. Odai, M. Ishizuka, T. Takeuchi

International Journal of Immunopharmacology 10(1) 4 1988年査読有り
IMMUNOSUPPRESSIVE ACTIVITY OF 15-DEOXYSPERGUALIN AND ITS EFFECT ON SKIN ALLOGRAFTS IN RATS

T MASUDA, S MIZUTANI, M IIJIMA, H ODAI, H SUDA, M ISHIZUKA, T TAKEUCHI, H UMEZAWA

JOURNAL OF ANTIBIOTICS 40(11) 1612-1618 1987年11月査読有り

MISC

Characterization of proteasome inhibitor-resistant human prostate cancer PC-3 cells

Isao Momose, Masatomi Iijima, Manabu Kawada, Daishiro Ikeda

MOLECULAR CANCER THERAPEUTICS 6(12) 3376S-3376S 2007年12月
Synthesis and activity of tyropeptin A derivatives as potent and selective inhibitors of mammalian 20S proteasome

Momose, I, Y Umezawa, S Hirosawa, M Iijima, H Iinuma, D Ikeda

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY 69(9) 1733-1742 2005年9月
ANTITUMOR EFFECT OF A NEW PROTEASOME INHIBITOR,TP-110, ON HUMAN PROSTATE CANCER

Isao Momose, Masatomi Iijima, Manabu Kawaba, Tohru Masuda, Daishiro Ikeda

ANTICANCER RESEARCH 24(5D) 3569-3569 2004年9月
Inhibition of ribonucleotide reductase activity by IC202C

M Iijima, T Someno, M Ishizuka, T Takeuchi

JOURNAL OF ANTIBIOTICS 54(8) 682-683 2001年8月
IC202B and C, new siderophores with immunosuppressive activity produced by Streptoalloteichus sp 1454-19

M Iijima, T Someno, M Ishizuka, R Sawa, H Naganawa, T Takeuchi

JOURNAL OF ANTIBIOTICS 52(9) 775-780 1999年9月
IC202A, a new siderophore with immunosuppressive activity produced by Streptoalloteichus sp. 1454-19 II. Physico-chemical properties and structure elucidation

M Iijima, T Someno, M Amemiya, R Sawa, H Naganawa, M Ishizuka, T Takeuchi

JOURNAL OF ANTIBIOTICS 52(1) 25-28 1999年1月
IC202A, a new siderophore with immunosuppressive activity produced by Streptoalloteichus sp. 1454-19. I. Taxonomy, fermentation, isolation and biological activity

Masatomi Iijima, Tetsuya Someno, Chiaki Imada, Yoshiro Okami, Masaaki Ishizuka, Tomio Takeuchi

Journal of Antibiotics 52(1) 20-24 1999年
ACTION OF CYTOGENIN ON LYMPHOID-CELLS AND THEIR CYTOKINE PRODUCTION

H KUMAGAI, M OSONO, M IIJIMA, M SAKASHITA, M ISHIZUKA, T TAKEUCHI

JOURNAL OF ANTIBIOTICS 48(4) 317-320 1995年4月
DELAMINOMYCINS, NOVEL EXTRACELLULAR-MATRIX RECEPTOR ANTAGONIST .4. STRUCTURE-ACTIVITY-RELATIONSHIPS OF DELAMINOMYCINS AND DERIVATIVES

M UENO, M AMEMIYA, K YAMAZAKI, M IIJIMA, M OSONO, T SOMENO, H IINUMA, M HAMADA, M ISHIZUKA, T TAKEUCHI

JOURNAL OF ANTIBIOTICS 46(7) 1156-1162 1993年7月
DELAMINOMYCINS, NOVEL NONPEPTIDE EXTRACELLULAR-MATRIX RECEPTOR ANTAGONIST AND A NEW CLASS OF POTENT IMMUNOMODULATOR .1. TAXONOMY, FERMENTATION, ISOLATION AND BIOLOGICAL-ACTIVITY

M UENO, M AMEMIYA, M IIJIMA, M OSONO, T MASUDA, N KINOSHITA, T IKEDA, H IINUMA, M HAMADA, M ISHIZUKA …

JOURNAL OF ANTIBIOTICS 46(5) 719-727 1993年5月
METACYTOFILIN, A NOVEL IMMUNOMODULATOR PRODUCED BY METARHIZIUM SP TA2759

M IIJIMA, T MASUDA, H NAKAMURA, H NAGANAWA, S KURASAWA, Y OKAMI, M ISHIZUKA, T TAKEUCHI, Y IITAKA

JOURNAL OF ANTIBIOTICS 45(9) 1553-1556 1992年9月
CYTOBLASTIN, A LOW-MOLECULAR-WEIGHT IMMUNOMODULATOR PRODUCED BY STREPTOVERTICILLIUM-EUROCIDICUM

H KUMAGAI, M IIJIMA, K DOBASHI, H NAGANAWA, T SAWA, M HAMADA, M ISHIZUKA, T TAKEUCHI

JOURNAL OF ANTIBIOTICS 44(9) 1029-1032 1991年9月
CONAGENIN, A LOW-MOLECULAR-WEIGHT IMMUNOMODULATOR PRODUCED BY STREPTOMYCES-ROSEOSPORUS

T YAMASHITA, M IIJIMA, H NAKAMURA, K ISSHIKI, H NAGANAWA, S HATTORI, M HAMADA, M ISHIZUKA, T TAKEUCHI

JOURNAL OF ANTIBIOTICS 44(5) 557-559 1991年5月
DEPSIDOMYCIN, A NEW IMMUNOMODULATING ANTIBIOTIC

K ISSHIKI, T SAWA, H NAGANAWA, Y KOIZUMI, N MATSUDA, M HAMADA, T TAKEUCHI, M IIJIMA, M OSONO

JOURNAL OF ANTIBIOTICS 43(9) 1195-1198 1990年9月
BIOLOGICAL-ACTIVITIES OF IC201 ((3S,8E)-1,3-DIHYDROXY-8-DECEN-5-ONE), A LOW-MOLECULAR WEIGHT IMMUNOMODULATOR PRODUCED BY STREPTOMYCES

S MIZUTANI, H ODAI, T MASUDA, M IIJIMA, M OSONO, M HAMADA, H NAGANAWA, M ISHIZUKA, T TAKEUCHI

JOURNAL OF ANTIBIOTICS 42(6) 952-959 1989年6月

所属学協会

共同研究・競争的資金等の研究課題

環状ペプチドの抗原虫作用機構に基づく原虫の分泌経路の解析と新たな創薬基盤の構築

日本学術振興会科学研究費助成事業基盤研究(C) 2022年4月 - 2025年3月

二瓶浩一, 飯島正富
複合的がん免疫療法の開発を志向したがん代謝阻害剤の探索

日本学術振興会科学研究費助成事業基盤研究(C) 2020年4月 - 2023年3月

百瀬功, 飯島正富
天然物由来抗癌物質の開発
development of anti-tumor substance

飯島正富

基本情報

研究キーワード

研究分野

学歴

論文

MISC

所属学協会

共同研究・競争的資金等の研究課題

メニュー

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