論文

2012年3月

From miracle fruit to transgenic tomato: mass production of the taste-modifying protein miraculin in transgenic plants

PLANT CELL REPORTS
  • Kyoko Hiwasa-Tanase
  • ,
  • Tadayoshi Hirai
  • ,
  • Kazuhisa Kato
  • ,
  • Narendra Duhita
  • ,
  • Hiroshi Ezura

31
3
開始ページ
513
終了ページ
525
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1007/s00299-011-1197-5
出版者・発行元
SPRINGER

The utility of plants as biofactories has progressed in recent years. Some recombinant plant-derived pharmaceutical products have already reached the marketplace. However, with the exception of drugs and vaccines, a strong effort has not yet been made to bring recombinant products to market, as cost-effectiveness is critically important for commercialization. Sweet-tasting proteins and taste-modifying proteins have a great deal of potential in industry as substitutes for sugars and as artificial sweeteners. The taste-modifying protein, miraculin, functions to change the perception of a sour taste to a sweet one. This taste-modifying function can potentially be used not only as a low-calorie sweetener but also as a new seasoning that could be the basis of a new dietary lifestyle. However, miraculin is far from inexpensive, and its potential as a marketable product has not yet been fully developed. For the last several years, biotechnological production of this taste-modifying protein has progressed extensively. In this review, the characteristics of miraculin and recent advances in its production using transgenic plants are summarized, focusing on such topics as the suitability of plant species as expression hosts, the cultivation method for transgenic plants, the method of purifying miraculin and future advances required to achieve industrial use.

Web of Science ® 被引用回数 : 19

リンク情報
DOI
https://doi.org/10.1007/s00299-011-1197-5
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000300249400007&DestApp=WOS_CPL

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