Kazuomi Nakamura

Profile Information

Affiliation: Tottori University Hospital, Tottori University

Degree: 博士（再生医科学）(鳥取大学)

J-GLOBAL ID: 201901019919111281
researchmap Member ID: B000364307

Research Interests

Research Areas

Life sciences / Laboratory animal science /

Research History

Apr, 2023 - Present

助教, 鳥取大学医学部附属病院新規医療研究推進センター
Apr, 2021 - Mar, 2023

Tottori University
Apr, 2018 - Mar, 2021

School of Life Sciences, Faculty of Medicine, Tottori University
Oct, 2014 - Mar, 2018

Research Center for Bioscience and Technology, Division of Laboratory Animal Science, Tottori University
Jul, 2013 - Sep, 2014

Research Center for Bioscience and Technology, Division of Laboratory Animal Science, Tottori University
Dec, 2011 - Jul, 2013

Research Center for Bioscience and Technology, Division of Laboratory Animal Science, Tottori University
Sep, 2010 - Dec, 2011

Research Center for Bioscience and Technology, Division of Laboratory Animal Science, Tottori University
Oct, 2008 - Aug, 2010

National Institutes of Biomedical Innovation, Health and Nutrition

Education

Apr, 2001 - Mar, 2003

Graduate School of Life and Environmental Science, Shimane University

Papers

High-temperature exposure during the early embryonic stage lowers core body temperature after growth via a hypothalamic Igfbp2-dependent mechanism.

Yuki Yoshimura, Tatsuo Watanabe, Kazuomi Nakamura, Akira Futatsugi, Katsuhiko Mikoshiba, Takeshi Y Hiyama

Scientific reports, 14(1) 29586-29586, Dec 3, 2024 Peer-reviewed
P2X4 receptor mediates macrophage infiltration leading to endometriotic cyst epithelium proliferation and hyperalgesia in mouse model

Hiroki Nagata, Takeshi Y. Hiyama, Misaki Inoue, Shanshan, Ikumi Wada, Yuki Yoshimura, Kazuomi Nakamur, Yukihiro Azuma, Tasuku Harada, Fuminori Taniguchi

F&S Science, Oct, 2024 Peer-reviewed
Role of tenascin C in lesion formation in early peritoneal endometriosis

Maako Moriyama, Kazuomi Nakamura, Hiroki Nagata, Ikumi Wada, Kei Nagira, Yukihiro Azuma, Eri Sato, Tasuku Harada, Fuminori Taniguchi

F&S science, 5(1) 69-79, Feb, 2024 Peer-reviewed
Long‐term culture induces Bax‐dependent apoptosis in rat preimplantation embryos

Kazuomi Nakamura, Misako Seno, Yuki Yoshimura, Osamu Suzuki

Molecular Reproduction and Development, 91(1), Oct 13, 2023 Peer-reviewedLead authorCorresponding author
Generation of c-Fos knockout rats, and observation of their phenotype

Yuki Yoshimura, Kazuomi Nakamura, Misako Seno, Misa Mochizuki, Kenji Kawai, Satoshi Koba, Tatsuo Watanabe

Experimental Animals, 72(1) 95-102, Feb, 2023 Peer-reviewed
Analysis of in vitro and in vivo metabolism of zidovudine and gemfibrozil in trans-chromosomic mouse line expressing human UGT2 enzymes.

Kaoru Kobayashi, Tsuneo Deguchi, Satoshi Abe, Naoyo Kajitani, Kanako Kazuki, Shoko Takehara, Kazuomi Nakamura, Atsushi Kurihara, Mitsuo Oshimura, Yasuhiro Kazuki

Pharmacology research & perspectives, 10(6) e01030, Dec, 2022 Peer-reviewed
Uromodulin Regulates Murine Aquaporin−2 Activity via Thick Ascending Limb–Collecting Duct Cross−Talk during Water Deprivation

Tomoaki Takata, Shintaro Hamada, Yukari Mae, Takuji Iyama, Ryohei Ogihara, Misako Seno, Kazuomi Nakamura, Miki Takata, Takaaki Sugihara, Hajime Isomoto

International Journal of Molecular Sciences, 23(16) 9410-9410, Aug 20, 2022 Peer-reviewed
Tracing location by applying Emerald luciferase in an early phase of murine endometriotic lesion formation.

Hermawan Wibisono, Kazuomi Nakamura, Fuminori Taniguchi, Misako Seno, Kayoko Morimoto, Yuki Yoshimura, Tasuku Harada

Experimental animals, 71(2) 184-192, Nov 25, 2021 Peer-reviewedCorresponding author
Role of IL-4 in bone marrow driven dysregulated angiogenesis and age-related macular degeneration

Takashi Baba, Dai Miyazaki, Kodai Inata, Ryu Uotani, Hitomi Miyake, Shin-ichi Sasaki, Yumiko Shimizu, Yoshitsugu Inoue, Kazuomi Nakamura

eLife, 9, May 5, 2020 Peer-reviewed
Tokishakuyakusan, a Kampo medicine, attenuates endometriosis-like lesions and hyperalgesia in murine with endometriosis-like symptoms.

Nagira K, Taniguchi F, Nakamura K, Tokita Y, Tsuchiya N, Khine YM, Harada T

American journal of reproductive immunology (New York, N.Y. : 1989), 82(5) e13182, Aug, 2019 Peer-reviewed
Novel dual-reporter transgenic rodents enable cell tracking in animal models of stem cell transplantation.

Morikawa K, Nakamura K, Suyama Y, Yamamoto K, Fukuoka K, Yagi S, Shirayoshi Y, Ohbayashi T, Hisatome I

Biochemistry and biophysics reports, 18 100645-100645, Jul, 2019 Peer-reviewed
New insights into the efficacy of SR-16234, a selective estrogen receptor modulator, on the growth of murine endometriosis-like lesions.

Khine YM, Taniguchi F, Nagira K, Nakamura K, Ohbayashi T, Osaki M, Harada T

American journal of reproductive immunology (New York, N.Y. : 1989), 80(5) e13023, Nov, 2018 Peer-reviewed
Inhibition of IAP (inhibitor of apoptosis) proteins represses inflammatory status via nuclear factor-kappa B pathway in murine endometriosis lesions

Fuminori Taniguchi, Takashi Uegaki, Kazuomi Nakamura, Khine Yin Mon, Takashi Harada, Tetsuya Ohbayashi, Tasuku Harada

AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY, 79(1), Jan, 2018 Peer-reviewed
Modification of single-nucleotide polymorphism in a fully humanized CYP3A mouse by genome editing technology

Satoshi Abe, Kaoru Kobayashi, Asami Oji, Tetsushi Sakuma, Kanako Kazuki, Shoko Takehara, Kazuomi Nakamura, Azusa Okada, Yasuko Tsukazaki, Naoto Senda …

SCIENTIFIC REPORTS, 7(1) 15189, Nov, 2017 Peer-reviewed
Lipopolysaccharide promotes the development of murine endometriosis-like lesions via the nuclear factor-kappa B pathway

Yukihiro Azuma, Fuminori Taniguchi, Kazuomi Nakamura, Kei Nagira, Yin Mon Khine, Tomoiki Kiyama, Takashi Uegaki, Masao Izawa, Tasuku Harada

AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY, 77(4), Apr, 2017 Peer-reviewed
The effect of supplementation of amino acids and taurine to modified KSOM culture medium on rat embryo development

Kazuomi Nakamura, Kayoko Morimoto, Kaoru Shima, Yuki Yoshimura, Yasuhiro Kazuki, Osamu Suzuki, Junichiro Matsuda, Tetsuya Ohbayashi

THERIOGENOLOGY, 86(8) 2083-2090, Nov, 2016 Peer-reviewedLead authorCorresponding author
Use of a Human Artificial Chromosome for Delivering Trophic Factors in a Rodent Model of Amyotrophic Lateral Sclerosis

Yasuhiro Watanabe, Yasuhiro Kazuki, Kanako Kazuki, Mitsutaka Ebiki, Mami Nakanishi, Kazuomi Nakamura, Miho Yoshida Yamakawa, Hiroyuki Hosokawa, Tetsuya Ohbayashi, Mitsuo Oshimura …

MOLECULAR THERAPY-NUCLEIC ACIDS, 4 e253, Oct, 2015 Peer-reviewed
Mouse embryonic stem cells with a multi-integrase mouse artificial chromosome for transchromosomic mouse generation

Yuki Yoshimura, Kazuomi Nakamura, Takeshi Endo, Naoyo Kajitani, Kanako Kazuki, Yasuhiro Kazuki, Hiroyuki Kugoh, Mitsuo Oshimura, Tetsuya Ohbayashi

TRANSGENIC RESEARCH, 24(4) 717-727, Aug, 2015 Peer-reviewed
Exploring new gene integration sites for gene knock-in by gene-trapping strategy

Isamu Nanchi, Yuki Yoshimura, Kazuomi Nakamura, Yusaku Masago, Tetsuya Ohbayashi, Tomohiko Okuda

TRANSGENIC RESEARCH, 24(3) 549-559, Jun, 2015 Peer-reviewed
Inhibitor of apoptosis proteins (IAPs) may be effective therapeutic targets for treating endometriosis

Takashi Uegaki, Fuminori Taniguchi, Kazuomi Nakamura, Mitsuhiko Osaki, Futoshi Okada, Osamu Yamamoto, Tasuku Harada

HUMAN REPRODUCTION, 30(1) 149-158, Jan, 2015 Peer-reviewed

Misc.

IL-4の血管内皮細胞における機能分化への関与

馬場高志, 宮崎大, 稲田耕大, 魚谷竜, 三宅瞳, 佐々木慎一, 清水由美子, 井上幸次, 中村和臣

眼科臨床紀要, 13(7) 502-502, Jul, 2020
加齢黄斑変性におけるIL-4の役割

馬場高志, 宮崎大, 稲田耕大, 魚谷竜, 三宅瞳, 佐々木慎一, 清水由美子, 井上幸次, 中村和臣

眼科臨床紀要, 13(5) 374-375, May, 2020
網膜血管内皮細胞および血管内皮前駆細胞の機能分化におけるIL-4の役割

宮崎大, 稲田耕大, 魚谷竜, 三宅瞳, 佐々木慎一, 馬場高志, 清水由美子, 井上幸次, 中村和臣, 大林徹也

日本眼科学会雑誌, 123(臨増) 187-187, Mar, 2019
神経栄養因子高発現型間葉系幹細胞のALSモデルマウスへの適正な移植条件の検討

恵比木満喬, 中村和臣, 細川洋行, 中西真実, 山川三穂, 渡辺保裕, 中島健二

神経治療学, 31(5) 657-657, Sep, 2014
ヒト人工染色体ベクターを用いたin vitro/in vivoデュアルバイオイメージングシステム

吉村祐貴, 中村和臣, 山口繁幸, 遠藤志穂, 中島芳浩, 香月康宏, 近江谷克裕, 押村光雄, 大林徹也

日本実験動物学会総会講演要旨集, 58th, 2011
発生中期マウス胎児における器官形成が観察可能なライブイメージングシステムの開発

吉村祐貴, 中村和臣, 中島芳浩, 香月康宏, 近江谷克裕, 押村光雄, 大林徹也

日本分子生物学会年会プログラム・要旨集(Web), 34th, 2011
SIK-KOマウスに観察される高脂肪食耐性の特徴

上尾達也, 熊谷彩子, 巽圭太, 森井英一, 中村和臣, 小浦美奈子, 松田潤一郎, 竹森洋

日本生化学会大会・日本分子生物学会年会合同大会講演要旨集, 83回・33回 4P-1016, Dec, 2010
塩誘導性キナーゼSIKは核内受容体の反応性を決定する

竹森洋, 上尾達也, 熊谷彩子, 伊東祐美, 秦野修, 早坂直人, 中村和臣, 小浦美奈子, 松田潤一郎

日本内分泌学会雑誌, 86(2) 408-408, Sep, 2010

Major Presentations

深層学習によるラット着床前胚の形態的分類

中村和臣, 妹尾美砂子

第71回日本実験動物学会総会, May 30, 2024
体外培養環境はラット着床前胚のミトコンドリア経路アポトーシスを誘導する

中村和臣, 妹尾美砂子, 吉村祐貴, 鈴木治

第70回日本実験動物学会総会, May 24, 2024
体外培養したラット着床前胚における網羅的遺伝子発現解析

中村和臣, 妹尾美砂子, 吉村祐貴, 鈴木治

第69回日本実験動物学会総会, May 18, 2022
体外培養したラット受精卵のDNA損傷

中村和臣, 妹尾美砂子, 小泉藍, 森本佳世子, 大林徹也

第66回日本実験動物学会, May 15, 2019
ラット卵管内液に基づいた栄養添加によるラット胚体外培養法

中村和臣, 森本佳世子, 島かおる, 吉村祐貴, 香月康宏, 鈴木治, 松田潤一郎, 大林徹也

第64回日本実験動物学会, May, 2017

Professional Memberships

Apr, 2011 - Present

JAPANESE ASSOCIATION FOR LABORATORY ANIMAL SCIENCE

Research Projects

The relevance of glucose transport and apoptosis in rat preimplantation embryos cultured in vitro

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2024 - Mar, 2027
子宮内膜症発生仮説としての「子宮内膜移植説」の解明：腹膜由来分子の役割に注目して

科学研究費助成事業基盤研究(C), 基盤研究(C), 日本学術振興会, Apr, 2021 - Mar, 2024

谷口文紀, 原田省, 中村和臣
ラットの着床前胚におけるミトコンドリア活性に関する研究

科学研究費助成事業若手研究, 若手研究, 日本学術振興会, Apr, 2020 - Mar, 2023

中村和臣
Studies on central command neurons and rat transgenesis

Grants-in-Aid for Scientific Research Grant-in-Aid for Challenging Research (Exploratory), Grant-in-Aid for Challenging Research (Exploratory), Japan Society for the Promotion of Science, Jul, 2020 - Mar, 2022

KOBA Satoshi
Development of a new culture method for rat pre-implantation embryos relative to amino acid metabolism

Grants-in-Aid for Scientific Research Grant-in-Aid for Early-Career Scientists, Grant-in-Aid for Early-Career Scientists, Japan Society for the Promotion of Science, Apr, 2018 - Mar, 2020

NAKAMURA Kazuomi
Improvement of techniques in generation of gene modified rat for drug discovery

Japan Science and Technology Agency, Nov, 2012 - Oct, 2013

Profile Information

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Research History

Education

Papers

Misc.

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