論文

査読有り
2014年12月

[A case of thymic cancer effectively treated by weekly paclitaxel combined with carboplatin].

Gan to kagaku ryoho. Cancer & chemotherapy
  • Rie Kondo
  • Satoshi Watanabe
  • Daisuke Ishikawa
  • Tomohiro Tanaka
  • Yasuyoshi Ohshima
  • Katsuaki Asakawa
  • Takuro Sakagami
  • Masaaki Okajima
  • Satoru Miura
  • Yoshiki Hayashi
  • Junta Tanaka
  • Hiroshi Kagamu
  • Hirohisa Yoshizawa
  • Ichiei Narita
  • 全て表示

41
13
開始ページ
2607
終了ページ
9
記述言語
日本語
掲載種別
研究論文(学術雑誌)

A 65-year-old woman with left chest pain, back pain, and palpitation that had persisted for 2 months was referred to our hospital. Computed tomography of her chest showed an anterior mediastinal tumor with mediastinal lymphadenopathy, left pleural effusion, and pericardial effusion. Endobronchial ultrasound-guided transbronchial needle aspiration of the subcarinal lymphadenopathy was performed. The pathological findings and other examinations such as bone scintigraphy suggested advanced thymic cancer (stage IV b according to the Masaoka classification of thymic epithelial tumors). The patient was treated with combination chemotherapy of carboplatin(area under the curve [AUC]=6, 656 mg/body, day 1) and weekly paclitaxel (70 mg/m², 100 mg/body, days 1, 8, and 15). After 4 cycles of chemotherapy, a partial response was achieved and the pericardial effusion disappeared. The patient did not experience any severe toxicity, except for grade 1 nausea, grade 2 anemia, and grade 2 alopecia. Weekly paclitaxel combined with carboplatin appears to be a useful regimen with minimal toxicity for advanced thymic cancer.

リンク情報
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/25596057
ID情報
  • ISSN : 0385-0684
  • PubMed ID : 25596057

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