J.M. Dijkstra

J-GLOBAL         Last updated: Nov 14, 2018 at 16:32
 
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Name
J.M. Dijkstra
E-mail
Dijkstrafujita-hu.ac.jp
Affiliation
藤田保健衛生大学
Section
Institute for Comprehensive Medical Science, Division of Biomedical Polymer Science
Job title
Senior assistant professor / Lecturer
Degree
Ph.D.

Profile

My Research Interests:
The immune system is characterized by a myriad of interacting cells and molecules, and it is probably outside our intellectual grasp to ever fully understand it. However, we can aspire to understand the central regulating mechanisms of the immune system in sufficient detail for being helpful with the establishment of therapies against disease. In order to find “central” regulating mechanisms, I try to compare the immune systems of various jawed vertebrate species, in the assumption that shared features are the most important features. My research has concentrated on the major histocompatibility complex (MHC), TCR co-receptors, and cytokines. The species that I worked with were mostly fish, but currently I am also investigating mammals.

Academic & Professional Experience

 
2014
 - 
Today
Senior Assistant Professor / Lecturer, Institute for Comprehensive Medical Science, Division of Biomedical Polymer Science, Fujita Health University
 
2004
 - 
2014
Assistant Professor, , Fujita Health University, Institute for Comprehensive Medical Science, Division of Biomedical Polymer Science
 
1997
 - 
2004
Postdoc, Immunology Group, National Research Institute for Aquaculture, Tamaki, Mie-ken, Japan
 
1994
 - 
1997
Ph.D. student, Institute of Molecular and Cellular Virology, Friedrich-Loeffler-Institutes, Insel Riems, Germany
 

Published Papers

 
J.M. Dijkstra, T. Yamaguchi
Immunogenetics   In press    Oct 2018   [Refereed]
A full-text view-only version of this paper is available at:
https://rdcu.be/barAX
Chen Z, Zhang N, Qi J, Chen R, Dijkstra JM, Li X, Wang Z, Wang J, Wu Y, Xia C
Journal of immunology (Baltimore, Md. : 1950)   199(10) 3668-3678   Nov 2017   [Refereed]
Yamaguchi T, Schares S, Fischer U, Dijkstra JM
Developmental and comparative immunology   65 268-279   Dec 2016   [Refereed]

Conference Activities & Talks

 
Major Histocompatibility Complex (MHC) in Fish
J.M. Dijkstra (invited speaker)
IGER Seminar, Topics in Advanced Biological Science, Nagoya University   14 Dec 2018   
The evolution of MHC structures [Invited]
J.M. Dijkstra (invited speaker)
Invited speaker and guest researcher at the Department of Microbiology and Immunology, College of Veterinary Medicine, China Agricultural University, Beijing, China   12 Oct 2018   
Evolution of short 4-alpha-helix cytokines, amongst which the related interleukins 2, 15 and 15-like
J.M. Dijkstra (speaker), U. Fischer, T. Yamaguchi
30th annual meeting of the Japanese Association for Developmental and Comparative Immunology (JADCI)   20 Aug 2018   
Along the Axis between Type 1 and Type 2 Immunity; Principles Conserved in Evolution from Fish to Mammals [Invited]
J.M. Dijkstra (invited speaker)
Mini Symposium Cell-mediated Immunity and - Infectious diseases in Fish, Tokyo University of Marine Science and Technology   22 Mar 2018   
Phylogeny of MHC (major histocompatibility complex) molecules
J.M. Dijkstra (speaker), U. Grimholt, K. Hashimoto
29th annual meeting of the Japanese Association for Developmental and Comparative Immunology (JADCI)   24 Aug 2017   

Research Grants & Projects

 
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(C))
Project Year: 2013 - 2015    Investigator(s): J・M Dijkstra
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(C))
Project Year: 2010 - 2012    Investigator(s): J・M Dijkstra
本研究では、MHCクラスII分子と免疫抑制的MHCクラスII受容体であるLAG-3を解析することにより、魚類のTregを解明し、さらに異なる近縁種から由来すると考えられている3種の異なったハプロイドゲノムを有するクローンのtriploidギンブナの起源を解析することを目的としている。我々はLAG-3の発現をTh2/Tregにシフトした免疫環境である鰓で見い出した。さらにギンブナMHCクラスIIを解析することに成功し、魚類MHCクラスIIの進化に関して大変興味深い研究結果を得ることができた。...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(C))
Project Year: 2007 - 2009    Investigator(s): Dijkstra J・M
The main project target was to elucidate the CD4 family of molecules in teleost fish, with clonal ginbuna crucian carp as major fish model. This family of molecules is known to form major markers for leukocyte subpopulations, predominantly of T ly...

Others

 
Other functions
Editiorial Board member of the journal: Immunogenetics.
Associate editor of the journal:
BMC Genomics.
Curator of the fish MHC section of the IPD-MHC nomenclature database (http://www.ebi.ac.uk/ipd/mhc/fish/index.html).
teaching experience: