論文

査読有り
2018年

An acute case of granulomatous amoebic encephalitis-Balamuthia mandrillaris infection

Internal Medicine
  • Kentarou Takei
  • ,
  • Masaya Toyoshima
  • ,
  • Masashi Nakamura
  • ,
  • Mineshige Sato
  • ,
  • Hiroshi Shimizu
  • ,
  • Chihiro Inoue
  • ,
  • Yoshio Shimizu
  • ,
  • Kenji Yagita

57
9
開始ページ
1313
終了ページ
1316
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.2169/internalmedicine.0011-17
出版者・発行元
Japanese Society of Internal Medicine

A 74-year-old woman who exhibited drowsiness was referred to our hospital. Enhanced head magnetic resonance imaging (MRI) revealed multiple ring-enhancing lesions and lesions showing partial mild hemorrhaging. The patient gradually progressed to a comatose condition with notable brain deterioration of unknown cause on follow-up MRI. On day nine, the patient inexplicably died, although brain herniation was suspected. Autopsy and histopathology revealed numerous amoebic trophozoites in the perivascular spaces and within the necrotic tissue. Brain immunostaining tested positive for Balamuthia mandrillaris. Infection due to free-living amoeba is rare in Japan
however, it may increase in the near future due to unknown reasons.

リンク情報
DOI
https://doi.org/10.2169/internalmedicine.0011-17
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/29321406
URL
http://orcid.org/0000-0002-3514-8166
ID情報
  • DOI : 10.2169/internalmedicine.0011-17
  • ISSN : 1349-7235
  • ISSN : 0918-2918
  • ORCIDのPut Code : 54698169
  • PubMed ID : 29321406
  • SCOPUS ID : 85046292086

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