2010年8月
Studies toward the total synthesis of armatol F: stereoselective construction of the C6 and C7 stereocenters and formation of the A-ring skeleton
TETRAHEDRON LETTERS
- ,
- ,
- ,
- ,
- 巻
- 51
- 号
- 32
- 開始ページ
- 4263
- 終了ページ
- 4266
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1016/j.tetlet.2010.06.026
- 出版者・発行元
- PERGAMON-ELSEVIER SCIENCE LTD
Armatol F, isolated from the red alga Chondria armata as a polyether triterpene, has a solitary oxepane (A-ring) and a fused tricyclic ether moiety (BCD-ring). The A-ring features a rare cis-relationship between the hydroxy group at the quaternary carbon C6 and the carbon chain at C7. As part of our program toward the total synthesis of armatol F, a new stereoselective method for the construction of the C6 and C7 stereocenters has been developed based on chirality-transferring Ireland-Claisen rearrangement. The A-ring skeleton has also been synthesized from the rearrangement product by a process including ring-closing olefin metathesis. (C) 2010 Elsevier Ltd. All rights reserved.
- リンク情報
- ID情報
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- DOI : 10.1016/j.tetlet.2010.06.026
- ISSN : 0040-4039
- CiNii Articles ID : 80021164783
- Web of Science ID : WOS:000280345800030