2014年5月
Reduced Intensity Conditioning in Allogeneic Stem Cell Transplantation for AML With Down Syndrome
PEDIATRIC BLOOD & CANCER
- 巻
- 61
- 号
- 5
- 開始ページ
- 925
- 終了ページ
- 927
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1002/pbc.24883
- 出版者・発行元
- WILEY-BLACKWELL
Allogeneic hematopoietic stem cell transplantation (HSCT) has not been widely used in patients with acute myeloid leukemia (AML) and Down syndrome (DS) due to fear of transplantation-related toxicity. A retrospective analysis of the outcome of allogeneic HSCT was conducted in 15 patients with AML and DS. The five patients transplanted with the reduced intensity conditioning (4 in complete remission (CR) and 1 in non-CR) had a significantly better survival rate than 10 patients transplanted with a conventional conditioning (4 in CR and 6 in non-CR) (3-year EFS (95% confidence interval): 80.0% (20.4-96.9%) vs. 10.0% (0.6%-35.8%), P=0.039). Pediatr Blood Cancer 2014;61:925-927. (c) 2013 Wiley Periodicals, Inc.
- リンク情報
-
- DOI
- https://doi.org/10.1002/pbc.24883
- PubMed
- https://www.ncbi.nlm.nih.gov/pubmed/24302531
- Web of Science
- https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000333485600029&DestApp=WOS_CPL
- URL
- http://europepmc.org/abstract/med/24302531
- URL
- http://orcid.org/0000-0002-5519-8320
- ID情報
-
- DOI : 10.1002/pbc.24883
- ISSN : 1545-5009
- eISSN : 1545-5017
- ORCIDのPut Code : 17609545
- PubMed ID : 24302531
- Web of Science ID : WOS:000333485600029