論文

2020年12月

Dosimetric evaluation with knowledge-based planning created at different periods in volumetric-modulated arc therapy for prostate cancer: a multi-institution study.

Radiological physics and technology
  • Hajime Monzen
  • ,
  • Mikoto Tamura
  • ,
  • Yoshihiro Ueda
  • ,
  • Jun-Ichi Fukunaga
  • ,
  • Tatsuya Kamima
  • ,
  • Yuta Muraki
  • ,
  • Kazuki Kubo
  • ,
  • Kiyoshi Nakamatsu

13
4
開始ページ
327
終了ページ
335
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1007/s12194-020-00585-0

Dosimetric evaluation and variation assessment were performed with two knowledge-based planning (KBP) models created at different periods for volumetric-modulated arc therapy (VMAT) for prostate cancer at five institutes. The first and second models (F- and S-models) for KBP were created before April 2017 and April 2019, respectively. The S-model was created using feedback plans from the F-model. Dose evaluation was compared between the two models using the same two computed tomography (CT) datasets and structures. The evaluation metrics were the dose received by 95.0% and 2.0% of the planning target volume (PTV); dose-volume parameters to the rectum and bladder as V90, V80, and V50; and monitor unit (MU). Dosimetric variation was compared by exporting estimated dose-volume histograms for each model to the Model Analytics website and assessing the organ at risk volume. There were no dosimetric differences between the two models for PTV. The V50 of the rectum in the S-model had improved compared to that of the F-model (case I: 49.3 ± 15.6 and 43.5 ± 15.2 [p = 0.08]; case II: 42.5 ± 16.9 and 36.0 ± 15.6 [p = 0.138]). The differences in other parameters were within ± 1.8% between the rectum and the bladder. The MU was slightly higher in the S-model than in the F-model, and dosimetric variation was reduced to the rectum and bladder among all the institutes. The polished S-model for KBP could be used for standardization of the plan quality and sharing of KBP models in VMAT for prostate cancer.

リンク情報
DOI
https://doi.org/10.1007/s12194-020-00585-0
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/32986184
ID情報
  • DOI : 10.1007/s12194-020-00585-0
  • PubMed ID : 32986184

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