Hiroyuki Mochizuki - My portal

Profile Information

Affiliation: Clinical Pathology Resident, Department of Population Health and Pathobiology, North Carolina State University

Degree: PhD(the University of Tokyo)
BVMS(the University of Tokyo)

J-GLOBAL ID: 201601021027191496
researchmap Member ID: B000257407

I am a veterinary clinical pathology resident at North Carolina State University. I provide clinical pathology diagnostic service, teach veterinary students and conduct basic and clinical research. Experience includes veterinary clinician (small animal) for 4 years and pre- and post-doctoral research for 10+ years.

Papers

Prognostic significance of hypermethylation of death-associated protein kinase (DAPK) gene CpG island in dogs with high-grade B-cell lymphoma.

Sato M, Mochizuki H, Goto-Koshino Y, Fujiwara-Igarashi A, Takahashi M, Ohno K, Tsujimoto H

Veterinary and comparative oncology, 16(3) 409-415, Mar, 2018 Peer-reviewed
Sequence analysis of RAS and RAF mutation hot spots in canine carcinoma

H. Mochizuki, M. Breen

VETERINARY AND COMPARATIVE ONCOLOGY, 15(4) 1598-1605, Dec, 2017 Peer-reviewed
Association of breed and histopathological grade in canine mast cell tumours

H. Mochizuki, A. Motsinger-Reif, C. Bettini, S. Moroff, M. Breen

VETERINARY AND COMPARATIVE ONCOLOGY, 15(3) 829-839, Sep, 2017 Peer-reviewed
Genomic profiling of canine mast cell tumors identifies DNA copy number aberrations associated with KIT mutations and high histological grade

Hiroyuki Mochizuki, Rachael Thomas, Scott Moroff, Matthew Breen

CHROMOSOME RESEARCH, 25(2) 129-143, Jun, 2017 Peer-reviewed
Genetic and epigenetic aberrations of p16 in feline primary neoplastic diseases and tumor cell lines of lymphoid and non-lymphoid origins

H. Mochizuki, A. Fujiwara-Igarashi, M. Sato, Y. Goto-Koshino, K. Ohno, H. Tsujimoto

VETERINARY JOURNAL, 219 27-33, Jan, 2017 Peer-reviewed
Detection of Copy Number Imbalance in Canine Urothelial Carcinoma With Droplet Digital Polymerase Chain Reaction

H. Mochizuki, S. G. Shapiro, M. Breen

VETERINARY PATHOLOGY, 53(4) 764-772, Jul, 2016 Peer-reviewed
Detection of BRAF Mutation in Urine DNA as a Molecular Diagnostic for Canine Urothelial and Prostatic Carcinoma

Hiroyuki Mochizuki, Susan G. Shapiro, Matthew Breen

PLOS ONE, 10(12) e0144170, Dec, 2015 Peer-reviewed
BRAF Mutations in Canine Cancers

Hiroyuki Mochizuki, Katherine Kennedy, Susan G. Shapiro, Matthew Breen

PLOS ONE, 10(6), Jun, 2015 Peer-reviewed
Construction of a multicolor GeneScan analytical system to detect clonal rearrangements of immunoglobulin and T cell receptor genes in canine lymphoid tumors

Yuko Goto-Koshino, Hiroyuki Mochizuki, Masahiko Sato, Ko Nakashima, Saaya Hiyoshi, Aki Fujiwara-Igarashi, Shingo Maeda, Kenji Nakamura, Kazuyuki Uchida, Yasuhito Fujino …

VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 165(1-2) 81-87, May, 2015 Peer-reviewed
Demonstration of the Cell Clonality in Canine Hematopoietic Tumors by X-chromosome Inactivation Pattern Analysis

H. Mochizuki, Y. Goto-Koshino, M. Takahashi, Y. Fujino, K. Ohno, H. Tsujimoto

VETERINARY PATHOLOGY, 52(1) 61-69, Jan, 2015 Peer-reviewed
Hypermethylation of the death-associated protein kinase CpG island in canine B-cell lymphoid tumors

Masahiko Sato, Hiroyuki Mochizuki, Yuko Goto-Koshino, Aki Fujiwara-Igarashi, Masashi Takahashi, Yasuhito Fujino, Koichi Ohno, Hajime Tsujimoto

VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 161(3-4) 222-231, Oct, 2014 Peer-reviewed
Inhibition of p16 tumor suppressor gene expression via promoter hypermethylation in canine lymphoid tumor cells

Aki Fujiwara-Igarashi, Yuko Goto-Koshino, Hiroyuki Mochizuki, Masahiko Sato, Yasuhito Fujino, Koichi Ohno, Hajime Tsujimoto

RESEARCH IN VETERINARY SCIENCE, 97(1) 60-63, Aug, 2014 Peer-reviewed
Chronic myelogenous leukaemia with persistent neutrophilia, eosinophilia and basophilia in a cat

Hiroyuki Mochizuki, Takahiro Seki, Yoshitaka Nakahara, Akitada Tomita, Masashi Takahashi, Yasuhito Fujino, Koichi Ohno, Hajime Tsujimoto

JOURNAL OF FELINE MEDICINE AND SURGERY, 16(6) 517-521, Jun, 2014 Peer-reviewed
Simultaneous Inactivation of the p16, p15 and p14 Genes Encoding Cyclin-Dependent Kinase Inhibitors in Canine T-Lymphoid Tumor Cells

Aki Fujiwara-Igarashi, Yuko Goto-Koshino, Hiroyuki Mochizuki, Shingo Maeda, Yasuhito Fujino, Koichi Ohno, Hajime Tsujimoto

JOURNAL OF VETERINARY MEDICAL SCIENCE, 75(6) 733-742, Jun, 2013 Peer-reviewed
X-Chromosome Inactivation Pattern Analysis for the Assessment of Cell Clonality in Cats

H. Mochizuki, Y. Goto-Koshino, M. Takahashi, Y. Fujino, K. Ohno, H. Tsujimoto

VETERINARY PATHOLOGY, 49(6) 963-970, Nov, 2012 Peer-reviewed
Comparison of the antitumor effects of an MDM2 inhibitor, nutlin-3, in feline lymphoma cell lines with or without p53 mutation

Hiroyuki Mochizuki, Yuko Goto-Koshino, Masahiko Sato, Yasuhito Fujino, Koichi Ohno, Hajime Tsujimoto

VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 147(3-4) 187-194, Jun, 2012 Peer-reviewed
Evaluation of the prognostic significance of BCL6 gene expression in canine high-grade B-cell lymphoma

Masahiko Sato, Hideyuki Kanemoto, Yumiko Kagawa, Tetsuya Kobayashi, Yuko Goto-Koshino, Hiroyuki Mochizuki, Masashi Takahashi, Yasuhito Fujino, Koichi Ohno, Hajime Tsujimoto

VETERINARY JOURNAL, 191(1) 108-114, Jan, 2012 Peer-reviewed
GeneScan analysis to detect clonality of T-cell receptor gamma gene rearrangement in feline lymphoid neoplasms

Hiroyuki Mochizuki, Kenji Nakamura, Hirofumi Sato, Yuko Goto-Koshino, Masahiko Sato, Masashi Takahashi, Kenjiro Fukushima, Ko Nakashima, Yasuhito Fujino, Koichi Ohno …

VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 145(1-2) 402-409, Jan, 2012 Peer-reviewed
Perfusion method for harvesting bone marrow cells from dogs

Masahiko Sato, Yuko Goto-Koshino, Hiroyuki Mochizuki, Yasuhito Fujino, Koichi Ohno, Hajime Tsujimoto

AMERICAN JOURNAL OF VETERINARY RESEARCH, 72(10) 1344-1348, Oct, 2011 Peer-reviewed
Multiplex PCR and Genescan analysis to detect immunoglobulin heavy chain gene rearrangement in feline B-cell neoplasms

Hiroyuki Mochizuki, Kenji Nakamura, Hirofumi Sato, Yuko Goto-Koshino, Masahiko Sato, Masashi Takahashi, Yasuhito Fujino, Koichi Ohno, Kazuyuki Uchida, Hiroyuki Nakayama …

VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 143(1-2) 38-45, Sep, 2011 Peer-reviewed