MISC

査読有り
2005年

Non-C<inf>2</inf>-symmetric, chirally economical, and readily tunable linked-binols: Design and application in a direct catalytic asymmetric mannich-type reaction

Angewandte Chemie - International Edition
  • Yoshida, T.
  • ,
  • Morimoto, H.
  • ,
  • Kumagai, N.
  • ,
  • Matsunaga, S.
  • ,
  • Shibasaki, M.

44
22
開始ページ
3470
終了ページ
3474
記述言語
英語
掲載種別
DOI
10.1002/anie.200500425
出版者・発行元
WILEY-V C H VERLAG GMBH

(Chemical Equation Presented) An achiral unit is shown to be better than a chiral unit in promoting an asymmetric reaction. Non-C2-symmetric linked-binols 1 with one chiral 1,1′-bi-2-naphthol unit and one flexible achiral unit are employed as ligands in direct catalytic asymmetric Mannich-type reactions (see scheme; TON = turnover number). With as little as 0.01 mol% of ligand 1 a and 0.04 mol% of Et2Zn, the reaction proceeded smoothly to give the product in 98% ee. © 2005 Wiley-VCH Verlag GmbH &amp; Co. KGaA.

Web of Science ® 被引用回数 : 66

リンク情報
DOI
https://doi.org/10.1002/anie.200500425
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/15861441
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000229549100024&DestApp=WOS_CPL
URL
http://www.scopus.com/inward/record.url?eid=2-s2.0-20444420552&partnerID=MN8TOARS
ID情報
  • DOI : 10.1002/anie.200500425
  • ISSN : 1433-7851
  • ORCIDのPut Code : 34143204
  • PubMed ID : 15861441
  • SCOPUS ID : 20444420552
  • Web of Science ID : WOS:000229549100024

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