Feb, 2001
Asymmetric synthesis of (+)-febrifugine and (+)-isofebrifugine using yeast reduction
TETRAHEDRON
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- Volume
- 57
- Number
- 7
- First page
- 1213
- Last page
- 1218
- Language
- English
- Publishing type
- Research paper (scientific journal)
- DOI
- 10.1016/S0040-4020(00)01109-1
- Publisher
- PERGAMON-ELSEVIER SCIENCE LTD
The antimalarial agents febrifugine (D-1) and isofebrifugine (D-2) were synthesized from chiral 3-piperidinol (D-4), which was asymmetrically prepared by the yeast reduction of 3-piperidone derivatives (DL-3), with dynamic optical resolution. (C) 2001 Elsevier Science Ltd. All rights reserved.
- Link information
- ID information
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- DOI : 10.1016/S0040-4020(00)01109-1
- ISSN : 0040-4020
- Web of Science ID : WOS:000166894100009