2017年6月
Unzipping and shearing DNA with electrophoresed nanoparticles in hydrogels
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
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- ,
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- 巻
- 19
- 号
- 21
- 開始ページ
- 13414
- 終了ページ
- 13418
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1039/c7cp02214j
- 出版者・発行元
- ROYAL SOC CHEMISTRY
We show electric control of unzipping and shearing dehybridization of a DNA duplex anchored to a hydrogel. Tensile force is applied by electrophoresing (25 V cm(-1)) gold nanoparticles pulling the DNA duplex. The pulled DNA strand is gradually released from the hydrogel. The unzipping release rate is faster than shearing; for example, 3-fold for a 15 base pair duplex, which helps to design electrically driven DNA devices.
- リンク情報
- ID情報
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- DOI : 10.1039/c7cp02214j
- ISSN : 1463-9076
- eISSN : 1463-9084
- PubMed ID : 28513698
- Web of Science ID : WOS:000402488300001