Papers

Peer-reviewed
Jun, 2014

Elevated audiovisual temporal interaction in patients with migraine without aura

JOURNAL OF HEADACHE AND PAIN
  • Weiping Yang
  • ,
  • Bingqian Chu
  • ,
  • Jiajia Yang
  • ,
  • Yinghua Yu
  • ,
  • Jinglong Wu
  • ,
  • Shengyuan Yu

Volume
15
Number
First page
44
Last page
Language
English
Publishing type
Research paper (scientific journal)
DOI
10.1186/1129-2377-15-44
Publisher
SPRINGER-VERLAG ITALIA SRL

Photophobia and phonophobia are the most prominent symptoms in patients with migraine without aura. Hypersensitivity to visual stimuli can lead to greater hypersensitivity to auditory stimuli, which suggests that the interaction between visual and auditory stimuli may play an important role in the pathogenesis of migraine. However, audiovisual temporal interactions in migraine have not been well studied. Therefore, our aim was to examine auditory and visual interactions in migraine.
In this study, visual, auditory, and audiovisual stimuli with different temporal intervals between the visual and auditory stimuli were randomly presented to the left or right hemispace. During this time, the participants were asked to respond promptly to target stimuli. We used cumulative distribution functions to analyze the response times as a measure of audiovisual integration.
Our results showed that audiovisual integration was significantly elevated in the migraineurs compared with the normal controls (p < 0.05); however, audiovisual suppression was weaker in the migraineurs compared with the normal controls (p < 0.05).
Our findings further objectively support the notion that migraineurs without aura are hypersensitive to external visual and auditory stimuli. Our study offers a new quantitative and objective method to evaluate hypersensitivity to audio-visual stimuli in patients with migraine.

Link information
DOI
https://doi.org/10.1186/1129-2377-15-44
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/24961903
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000339345700001&DestApp=WOS_CPL
ID information
  • DOI : 10.1186/1129-2377-15-44
  • ISSN : 1129-2369
  • eISSN : 1129-2377
  • Pubmed ID : 24961903
  • Web of Science ID : WOS:000339345700001

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