2016年1月
Can Postural Instability Respond to Galvanic Vestibular Stimulation in Patients with Parkinson's Disease?
Journal of movement disorders
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- 巻
- 9
- 号
- 1
- 開始ページ
- 40
- 終了ページ
- 3
- 記述言語
- 英語
- 掲載種別
- DOI
- 10.14802/jmd.15030
OBJECTIVE: Galvanic vestibular stimulation (GVS) activates the vestibular afferents, and these changes in vestibular input exert a strong influence on the subject's posture or standing balance. In patients with Parkinson's disease (PD), vestibular dysfunction might contribute to postural instability and gait disorders. METHODS: Current intensity was increased to 0.7 mA, and the current was applied to the patients for 20 minutes. To perform a sham stimulation, the current intensity was increased as described and then decreased to 0 mA over the course of 10 seconds. The patient's status was recorded continuously for 20 minutes with the patient in the supine position. RESULTS: Three out of 5 patients diagnosed with PD with postural instability and/or abnormal axial posture showed a reduction in postural instability after GVS. The score for item 12 of the revised Unified Parkinson's Disease Rating Scale part 3 was decreased in these patients. CONCLUSIONS: The mechanism of postural instability is complex and not completely understood. In 2 out of the 5 patients, postural instability was not changed in response to GVS. Nonetheless, the GVS-induced change in postural instability for 3 patients in our study suggests that GVS might be a therapeutic option for postural instability.
- リンク情報
- ID情報
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- DOI : 10.14802/jmd.15030
- PubMed ID : 26648182
- PubMed Central 記事ID : PMC4734983