Oba Junna - My portal

Profile Information

Affiliation: Senior Assistant Professor (Non-tenured)/Assistant Professor (Non-tenured), School of Medicine Department of Extended Intelligence for Medicine, The Ishii-Ishibashi Laboratory, Keio University

Degree: 医師(熊本大学医学部)
博士（医学）(九州大学大学院医学系学府)
Medical Doctor (MD)(Kumamoto University School of Medicine)
Doctor of Philosophy (PhD)(Kyushu University Graduate School of Medicine)

Other name(s) (e.g. nickname): Maiden name: Okada
Researcher number: 60644721
ORCID ID: https://orcid.org/0000-0002-2899-3919
J-GLOBAL ID: 202101019062415980
researchmap Member ID: R000031115

External link: https://www.researchgate.net/profile/Junna_Oba

Research History

Apr, 2022 - Present

Senior Assistant Professor (Non-tenured)/Assistant Professor (Non-tenured), School of Medicine, Department of Extended Intelligence for Medicine, The Ishii-Ishibashi Laboratory （Shinanomachi）
Nov, 2021 - Mar, 2022

Assistant Professor, Department of Extended Intelligence for Medicine, The Ishii-Ishibashi Laboratory, Keio University School of Medicine
Oct, 2019 - Oct, 2021

Project lecturer, Genomics Unit, Cancer Center, Keio University School of Medicine
May, 2018 - Sep, 2019

Instructor, Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center
Jul, 2016 - Apr, 2018

Senior Research Scientist, Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center
Sep, 2015 - Jun, 2016

Research Assistant, Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center
May, 2013 - Aug, 2015

Postdoctoral research fellow, Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center
Apr, 2012 - Mar, 2013

Clinical fellow, Dermatology, Kyushu University Hospital
Apr, 2005 - Mar, 2007

Clinical fellow, Dermatology, Inatsuki Hospital
Apr, 2004 - Mar, 2005

Resident, Dermatology, Kyushu University Hospital
May, 2003 - Mar, 2004

Resident, Internal Medicine, National Hospital Organization Kyushu Medical Center

Education

Apr, 2007 - Mar, 2012

Graduate School of Medicine, Kyushu University
Apr, 1996 - Mar, 2003

School of Medicine, Kumamoto University

Papers

Using a Systems Engineering Approach to Build a PCR Testing System at a Medical School During the COVID-19 Pandemic

Junna Oba, Masako Toriya, Yoshifumi Uwamino, Koichi Matsuo

Risk Management and Healthcare Policy, Volume 17 649-662, Mar, 2024
Multi-modal molecular programs regulate melanoma cell state.

Miles C Andrews, Junna Oba, Chang-Jiun Wu, Haifeng Zhu, Tatiana Karpinets, Caitlin A Creasy, Marie-Andrée Forget, Xiaoxing Yu, Xingzhi Song, Xizeng Mao …

Nature communications, 13(1) 4000-4000, Jul 9, 2022
SARS-CoV-2 RT-qPCR testing of pooled saliva samples: A case study of 824 asymptomatic individuals and a questionnaire survey in Japan.

Junna Oba, Hiroaki Taniguchi, Masae Sato, Masaki Takanashi, Moe Yokemura, Yasunori Sato, Hiroshi Nishihara

PloS one, 17(5) e0263700, 2022
Reprogramming of bivalent chromatin states in NRAS mutant melanoma suggests PRC2 inhibition as a therapeutic strategy

Terranova C.J, Tang M, Maitituoheti M, Raman A.T, Ghosh A.K, Schulz J, Amin S.B, Orouji E, Tomczak K, Sarkar S …

Cell Reports, 36(3) 109410, Jul 20, 2021 Peer-reviewed
The genetic and epigenetic basis of distinct melanoma types

Oba J, Woodman S.E

Journal of Dermatology, 48(7) 925-939, Jul, 2021 Peer-reviewedInvited
Estimating copy number using next-generation sequencing to determine ERBB2 amplification status

Nakamura K, Aimono E, Oba J, Hayashi H, Tanishima S, Hayashida T, Chiyoda T, Kosaka T, Hishida T, Kawakubo H …

Medical Oncology, 38(4) 36, Apr, 2021 Peer-reviewed
RT-PCR screening tests for SARS-CoV-2 with saliva samples in asymptomatic people: Strategy to maintain social and economic activities while reducing the risk of spreading the virus

Oba J, Taniguchi H, Sato M, Takamatsu R, Morikawa S, Nakagawa T, Takaishi H, Saya H, Matsuo K, Nishihara H

Keio Journal of Medicine, 70(2) 35-43, 2021 Peer-reviewed
Pulmonary metastasis secondary to abiraterone-resistant prostate cancer with homozygous deletions of BRCA2: First Japanese case

Izawa M, Kosaka T, Nakamura K, Oba J, Hishida T, Hongo H, Mikami S, Nishihara H, Oya M

IJU Case Reports, 4(1) 14-17, Jan, 2021 Peer-reviewed
The expression of cd74-regulated inflammatory markers in stage iv melanoma: Risk of cns metastasis and patient survival

Ogata D, Roszik J, Oba J, Kim S.H, Bassett R.L, Haydu L.E, Tanese K, Grimm E.A, Ekmekcioglu S

Cancers, 12(12) 1-13, Dec, 2020 Peer-reviewed
Elevated endogenous SDHA drives pathological metabolism in highly metastatic uveal melanoma

Chattopadhyay C, Oba J, Roszik J, Marszalek J.R, Chen K, Qi Y, Eterovic K, Gordon Robertson A, Burks J.K, McCannel T.A …

Investigative Ophthalmology and Visual Science, 60(13) 4187-4195, Oct 1, 2019 Peer-reviewed
Tyrosine Kinase Inhibitor and Immune Checkpoint Inhibitor Responses in KIT-Mutant Metastatic Melanoma

McKean M, Oba J, Ma J, Roth K.G, Wang W.L, Macedo M.P, Carapeto F.C.L, Haydu L.E, Siroy A.E, Vo P …

Journal of Investigative Dermatology, 139(3) 728-731, Mar, 2019 Peer-reviewed
CD38-mediated immunosuppression as a mechanism of tumor cell escape from PD-1/PD-l1 blockade

Chen L, Diao L, Yang Y, Yi X, Rodriguez B.L, Li Y, Villalobos P.A, Cascone T, Liu X, Tan L …

Cancer Discovery, 8(9) 1156-1175, Sep, 2018 Peer-reviewed
Non-corticosteroid adherence and itch severity influence perception of itch in atopic dermatitis

Takeuchi S, Oba J, Esaki H, Furue M

Journal of Dermatology, 45(2) 158-164, Feb, 2018 Peer-reviewed
Targeting the HGF/MET Axis counters primary resistance to KIT inhibition in KIT-mutant melanoma

Oba J, Kim S.H, Wang W.L, Macedo M.P, Carapeto F, McKean M.A, Van Arnam J, Eterovic A.K, Sen S, Kale C.R., Yu X …

JCO Precision Oncology, 2, 2018 Peer-reviewed
Integrative analysis identifies four molecular and clinical subsets in uveal melanoma

Robertson AG, Shih J, Yau C, Gibb EA, Oba J, Mungall KL, Hess JM, Uzunangelov V, Walter V, Danilova L …

Cancer Cell, 32(2) 204-220, Aug 14, 2017 Peer-reviewed
Trends in hepatocyte growth factor, insulin-like growth factor 1, thyroid-stimulating hormone, and leptin expression levels in uveal melanoma patient serum and tumor tissues: correlation to disease progression

Oba, J, Esmaeli, B, Ellerhorst, J. A, Lyons, G. R, Milton, D. R, Wang, W. L, Macedo, M. P, Lazar, A. J, Grimm, E. A, Chattopadhyay, C

Melanoma Res, 27(2) 126-133, Apr, 2017 Peer-reviewed
Novel algorithmic approach predicts tumor mutation load and correlates with immunotherapy clinical outcomes using a defined gene mutation set

Roszik, J, Haydu, L. E, Hess, K. R, Oba, J, Joon, A. Y, Siroy, A. E, Karpinets, T. V, Stingo, F. C, Baladandayuthapani, V, Tetzlaff, M. T …

BMC Med, 14(1) 168, Oct 25, 2016 Peer-reviewed
Uveal melanoma: From diagnosis to treatment and the science in between

Chattopadhyay, C, Kim, D. W, Gombos, D. S, Oba, J, Qin, Y, Williams, M. D, Esmaeli, B, Grimm, E. A, Wargo, J. A, Woodman, S. E …

Cancer, 122(15) 2299-312, Aug 1, 2016 Peer-reviewed
Elevated Serum Leptin Levels are Associated With an Increased Risk of Sentinel Lymph Node Metastasis in Cutaneous Melanoma

Oba, J, Wei, W, Gershenwald, J. E, Johnson, M. M, Wyatt, C. M, Ellerhorst, J. A, Grimm, E. A

Medicine (Baltimore), 95(11) e3073, Mar, 2016 Peer-reviewed
CD10-Equipped Melanoma Cells Acquire Highly Potent Tumorigenic Activity: A Plausible Explanation of Their Significance for a Poor Prognosis

Oba, J, Nakahara, T, Hashimoto-Hachiya, A, Liu, M, Abe, T, Hagihara, A, Yokomizo, T, Furue, M

PLoS One, 11(2) e0149285, 2016 Peer-reviewed

Misc.

次世代シーケンサーを用いたゲノム解析による、ERBB2増幅症例での治療推奨におけるコピー数のカットオフ値の標準化について

中村康平, 四十物絵理子, 大場純奈, 植木有紗, 今井光穂, 柳田絵美衣, 山田寛, 林秀幸, 西原広史

日本癌学会総会記事, 79回 OJ7-2, Oct, 2020
治療早期のがん患者に対するスクリーニング遺伝子検査の診断的有用性について

四十物絵理子, 中村康平, 柳田絵美衣, 山田寛, 佐々木瑛里, 林秀幸, 谷嶋成樹, 大場純奈, 西原広史

日本癌学会総会記事, 79回 OE15-1, Oct, 2020
FFPE組織由来DNAの品質と遺伝子パネル検査のシーケンス成功率の検討

柳田絵美衣, 山田寛, 高松玲佳, 松岡亮介, 四十物絵理子, 中村康平, 林秀幸, 谷嶋成樹, 大場純奈, 西原広史

日本癌学会総会記事, 79回 OJ7-3, Oct, 2020

Research Projects

Building a versatile medical test system in a pandemic

Grant-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), MEXT,JSPS, Apr, 2021 - Mar, 2024

大場純奈