Koji Nishiguchi

J-GLOBAL         Last updated: Aug 29, 2019 at 22:56
 
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Name
Koji Nishiguchi
Affiliation
Tohoku University

Profile

Education
1991 – 1997: School of Medicine, Nagoya University, Nagoya, Japan
2001 – 2005: Graduate School of Medicine, Nagoya University, Nagoya, Japan

Employment
2014 - Present:Associate Professor,Tohoku University Graduate School of Medicine
2012 - 2013: Clinical Research Associate, UCL, Institute of Ophthalmology
2011: Research fellow, Department of Medical Genetics, University of Lausanne
2007 – 2011: Assistant professor of Ophthalmology, Nagoya University School of Medicine
2002 – 2004: Research Fellow in Ophthalmic Pathology, Massachusetts Eye and Ear Infirmary, Harvard Medical School
2000 - 2001: Research Fellow, Schepens Eye Research Institute, Harvard Medical School
1999 – 2005: Resident, Ophthalmology, Nagoya University Hospital, Japan
1997 – 1999: Resident of General Medicine/Emergency Medicine, Nagoya Daini Red Cross Hospital

Research Areas

 
 

Published Papers

 
Koyanagi Y, Akiyama M, Nishiguchi KM, Momozawa Y, Kamatani Y, Takata S, Inai C, Iwasaki Y, Kumano M, Murakami Y, Omodaka K, Abe T, Komori S, Gao D, Hirakata T, Kurata K, Hosono K, Ueno S, Hotta Y, Murakami A, Terasaki H, Wada Y, Nakazawa T, Ishibashi T, Ikeda Y, Kubo M, Sonoda KH
Journal of medical genetics      Jun 2019   [Refereed]
Verbakel SK, van Huet RAC, den Hollander AI, Geerlings MJ, Kersten E, Klevering BJ, Klaver CCW, Plomp AS, Wesseling NL, Bergen AAB, Nikopoulos K, Rivolta C, Ikeda Y, Sonoda KH, Wada Y, Boon CJF, Nakazawa T, Hoyng CB, Nishiguchi KM
Investigative ophthalmology & visual science   60(4) 1192-1203   Mar 2019   [Refereed]
Sato R, Kunikata H, Asano T, Aizawa N, Kiyota N, Shiga Y, Nishiguchi KM, Kato K, Nakazawa T
Scientific reports   9(1) 8875   Jun 2019   [Refereed]
Nikopoulos K, Cisarova K, Quinodoz M, Koskiniemi-Kuendig H, Miyake N, Farinelli P, Rehman AU, Khan MI, Prunotto A, Akiyama M, Kamatani Y, Terao C, Miya F, Ikeda Y, Ueno S, Fuse N, Murakami A, Wada Y, Terasaki H, Sonoda KH, Ishibashi T, Kubo M, Cremers FPM, Kutalik Z, Matsumoto N, Nishiguchi KM, Nakazawa T, Rivolta C
Nature communications   10(1) 2884   Jun 2019   [Refereed]
Nishiguchi KM, Ikeda Y, Fujita K, Kunikata H, Akiho M, Hashimoto K, Hosono K, Kurata K, Koyanagi Y, Akiyama M, Suzuki T, Kawasaki R, Wada Y, Hotta Y, Sonoda KH, Murakami A, Nakazawa M, Nakazawa T, Abe T
Ophthalmology      Jun 2019   [Refereed]
Nishiguchi KM, Yokoyama Y, Kunikata H, Abe T, Nakazawa T
The British journal of ophthalmology   103(4) 475-480   Apr 2019   [Refereed]
Nishiguchi KM, Aoki M, Nakazawa T, Abe T
Ophthalmic genetics   40(1) 49-53   Feb 2019   [Refereed]
Nishiguchi KM, Fujita K, Inoue T, Nakazawa T
Clinical & experimental ophthalmology   47(1) 148-149   Jan 2019   [Refereed]
Single AAV-mediated scarless genome editing in dysfunctional retinal neurons mediates robust visual restoration in mice
Koji Nishiguchi
bioRxiv   552653   2019
Tokashiki N, Nishiguchi KM, Fujita K, Sato K, Nakagawa Y, Nakazawa T
Scientific reports   8(1) 15948   Oct 2018   [Refereed]
Nishiguchi KM, Fujita K, Tokashiki N, Komamura H, Takemoto-Kimura S, Okuno H, Bito H, Nakazawa T
Molecular therapy : the journal of the American Society of Gene Therapy   26(10) 2397-2406   Oct 2018   [Refereed]
Sato K, Saigusa D, Saito R, Fujioka A, Nakagawa Y, Nishiguchi KM, Kokubun T, Motoike IN, Maruyama K, Omodaka K, Shiga Y, Uruno A, Koshiba S, Yamamoto M, Nakazawa T
Scientific reports   8(1) 11930   Aug 2018   [Refereed]
Sato K, Shiga Y, Nakagawa Y, Fujita K, Nishiguchi KM, Tawarayama H, Murayama N, Maekawa S, Yabana T, Omodaka K, Katayama S, Feng Q, Tsuda S, Nakazawa T
Investigative ophthalmology & visual science   59(10) 3943-3951   Aug 2018   [Refereed]
Kunikata H, Fujita K, Nishiguchi KM, Nakazawa T
Clinical & experimental ophthalmology   46(5) 556-558   Jul 2018   [Refereed]
Nishiguchi KM, Fujita K, Inoue T, Nakazawa T
Clinical & experimental ophthalmology   46(9) 1087-1089   Jun 2018   [Refereed]
Ichinohasama R, Nishiguchi KM, Fujita K, Aizawa N, Inoue T, Sasaki E, Kunikata H, Nakazawa T
Current eye research   43(6) 804-809   Jun 2018   [Refereed]
Shiga Y, Akiyama M, Nishiguchi KM, Sato K, Shimozawa N, Takahashi A, Momozawa Y, Hirata M, Matsuda K, Yamaji T, Iwasaki M, Tsugane S, Oze I, Mikami H, Naito M, Wakai K, Yoshikawa M, Miyake M, Yamashiro K, Japan Glaucoma Society Omics Group (JGS-OG)., Kashiwagi K, Iwata T, Mabuchi F, Takamoto M, Ozaki M, Kawase K, Aihara M, Araie M, Yamamoto T, Kiuchi Y, Nakamura M, Ikeda Y, Sonoda KH, Ishibashi T, Nitta K, Iwase A, Shirato S, Oka Y, Satoh M, Sasaki M, Fuse N, Suzuki Y, Cheng CY, Khor CC, Baskaran M, Perera S, Aung T, Vithana EN, Cooke Bailey JN, Kang JH, Pasquale LR, Haines JL, NEIGHBORHOOD Consortium., Wiggs JL, Burdon KP, Gharahkhani P, Hewitt AW, Mackey DA, MacGregor S, Craig JE, Allingham RR, Hauser M, Ashaye A, Budenz DL, Akafo S, Williams SEI, Kamatani Y, Nakazawa T, Kubo M
Human molecular genetics   27(8) 1486-1496   Apr 2018   [Refereed]
Ikeda Y, Nishiguchi KM, Miya F, Shimozawa N, Funatsu J, Nakatake S, Fujiwara K, Tachibana T, Murakami Y, Hisatomi T, Yoshida S, Yasutomi Y, Tsunoda T, Nakazawa T, Ishibashi T, Sonoda KH
Investigative ophthalmology & visual science   59(2) 826-830   Feb 2018   [Refereed]
Fukuda M, Omodaka K, Tatewaki Y, Himori N, Matsudaira I, Nishiguchi KM, Murata T, Taki Y, Nakazawa T
PloS one   13(7) e0197027   2018   [Refereed]
Himori N, Kunikata H, Inoue M, Takeshita T, Nishiguchi KM, Nakazawa T
Acta ophthalmologica   95(8) e799-e800   Dec 2017   [Refereed]
Maekawa S, Sato K, Fujita K, Daigaku R, Tawarayama H, Murayama N, Moritoh S, Yabana T, Shiga Y, Omodaka K, Maruyama K, Nishiguchi KM, Nakazawa T
Scientific reports   7(1) 6885   Jul 2017   [Refereed]
Fujita K, Nishiguchi KM, Shiga Y, Nakazawa T
Molecular therapy. Methods & clinical development   5 130-141   Jun 2017   [Refereed]
Yamamoto K, Sato K, Yukita M, Yasuda M, Omodaka K, Ryu M, Fujita K, Nishiguchi KM, Machida S, Nakazawa T
Journal of neurochemistry   140(3) 495-508   Feb 2017   [Refereed]
Yukita M, Omodaka K, Machida S, Yasuda M, Sato K, Maruyama K, Nishiguchi KM, Nakazawa T
Current eye research   42(1) 125-133   Jan 2017   [Refereed]
Shiga Y, Nishiguchi KM, Kawai Y, Kojima K, Sato K, Fujita K, Takahashi M, Omodaka K, Araie M, Kashiwagi K, Aihara M, Iwata T, Mabuchi F, Takamoto M, Ozaki M, Kawase K, Fuse N, Yamamoto M, Yasuda J, Nagasaki M, Nakazawa T, Japan Glaucoma Society Omics Group (JGS-OG).
PloS one   12(12) e0186678   2017   [Refereed]
Mabuchi F, Mabuchi N, Sakurada Y, Yoneyama S, Kashiwagi K, Iijima H, Yamagata Z, Takamoto M, Aihara M, Iwata T, Kawase K, Shiga Y, Nishiguchi KM, Nakazawa T, Ozaki M, Araie M, Japan Glaucoma Society Omics Group (JGS-OG).
PloS one   12(8) e0183709   2017   [Refereed]
Inoue M, Himori N, Kunikata H, Takeshita T, Aizawa N, Shiga Y, Omodaka K, Nishiguchi KM, Takahashi H, Nakazawa T
Acta ophthalmologica   94(7) e580-e585   Nov 2016   [Refereed]
Hashimoto K, Kunikata H, Yasuda M, Ito A, Aizawa N, Sawada S, Kondo K, Satake C, Takano Y, Nishiguchi KM, Katagiri H, Nakazawa T
Journal of diabetes and its complications   30(7) 1371-1377   Sep 2016   [Refereed]
Yasuda M, Tanaka Y, Omodaka K, Nishiguchi KM, Nakamura O, Tsuda S, Nakazawa T
Scientific reports   6 28736   Jun 2016   [Refereed]
Sato K, Nishiguchi KM, Maruyama K, Moritoh S, Fujita K, Ikuta Y, Kasai H, Nakazawa T
Journal of negative results in biomedicine   15 5   Mar 2016   [Refereed]
Nishiguchi KM, Yokoyama Y, Fujii Y, Fujita K, Tomiyama Y, Kawasaki R, Furukawa T, Ono F, Shimozawa N, Togo M, Suzuki M, Nakazawa T
PloS one   11(10) e0164899   2016   [Refereed]
Tomiyama Y, Fujita K, Nishiguchi KM, Tokashiki N, Daigaku R, Tabata K, Sugano E, Tomita H, Nakazawa T
PloS one   11(6) e0156927   2016   [Refereed]
Corton M, Nishiguchi KM, Avila-Fernández A, Nikopoulos K, Riveiro-Alvarez R, Tatu SD, Ayuso C, Rivolta C
PloS one   11(3) e0153121   2016   [Refereed]
Wang Z, Iida A, Miyake N, Nishiguchi KM, Fujita K, Nakazawa T, Alswaid A, Albalwi MA, Kim OH, Cho TJ, Lim GY, Isidor B, David A, Rustad CF, Merckoll E, Westvik J, Stattin EL, Grigelioniene G, Kou I, Nakajima M, Ohashi H, Smithson S, Matsumoto N, Nishimura G, Ikegawa S
PloS one   11(3) e0150555   2016   [Refereed]
Fujita K, Nishiguchi KM, Yokoyama Y, Tomiyama Y, Tsuda S, Yasuda M, Maekawa S, Nakazawa T
Scientific reports   5 18141   Dec 2015   [Refereed]
Saqib MA, Nikopoulos K, Ullah E, Sher Khan F, Iqbal J, Bibi R, Jarral A, Sajid S, Nishiguchi KM, Venturini G, Ansar M, Rivolta C
Scientific reports   5 9965   May 2015   [Refereed]
Aboshiha J, Dubis AM, van der Spuy J, Nishiguchi KM, Cheeseman EW, Ayuso C, Ehrenberg M, Simonelli F, Bainbridge JW, Michaelides M
Ophthalmology   122(4) 862-864   Apr 2015   [Refereed]
Yukita M, Machida S, Nishiguchi KM, Tsuda S, Yokoyama Y, Yasuda M, Maruyama K, Nakazawa T
Documenta ophthalmologica. Advances in ophthalmology   130(2) 149-156   Apr 2015   [Refereed]
Nishiguchi KM, Carvalho LS, Rizzi M, Powell K, Holthaus SM, Azam SA, Duran Y, Ribeiro J, Luhmann UF, Bainbridge JW, Smith AJ, Ali RR
Nature communications   6 6006   Jan 2015   [Refereed]
Yasuda M, Tanaka Y, Nishiguchi KM, Ryu M, Tsuda S, Maruyama K, Nakazawa T
BMC genomics   15 982   Nov 2014   [Refereed]
Omodaka K, Nishiguchi KM, Yasuda M, Tanaka Y, Sato K, Nakamura O, Maruyama K, Nakazawa T
Brain research   1586 203-212   Oct 2014   [Refereed]
Yokoyama Y, Maruyama K, Yamamoto K, Omodaka K, Yasuda M, Himori N, Ryu M, Nishiguchi KM, Nakazawa T
Biochemical and biophysical research communications   451(4) 510-515   Sep 2014   [Refereed]
Nishiguchi KM, Avila-Fernandez A, van Huet RA, Corton M, Pérez-Carro R, Martín-Garrido E, López-Molina MI, Blanco-Kelly F, Hoefsloot LH, van Zelst-Stams WA, García-Ruiz PJ, Del Val J, Di Gioia SA, Klevering BJ, van de Warrenburg BP, Vazquez C, Cremers FP, García-Sandoval B, Hoyng CB, Collin RW, Rivolta C, Ayuso C
Ophthalmology   121(8) 1620-1627   Aug 2014   [Refereed]
Tanaka Y, Tsuda S, Kunikata H, Sato J, Kokubun T, Yasuda M, Nishiguchi KM, Inada T, Nakazawa T
Scientific reports   4 5089   May 2014   [Refereed]
Nishiguchi KM, Tearle RG, Liu YP, Oh EC, Miyake N, Benaglio P, Harper S, Koskiniemi-Kuendig H, Venturini G, Sharon D, Koenekoop RK, Nakamura M, Kondo M, Ueno S, Yasuma TR, Beckmann JS, Ikegawa S, Matsumoto N, Terasaki H, Berson EL, Katsanis N, Rivolta C
Proceedings of the National Academy of Sciences of the United States of America   110(40) 16139-16144   Oct 2013   [Refereed]
Ueno S, Nishiguchi KM, Tanioka H, Enomoto A, Yamanouchi T, Kondo M, Yasuma TR, Yasuda S, Kuno N, Takahashi M, Terasaki H
PloS one   8(11) e81507   2013   [Refereed]
Corton M, Nishiguchi KM, Avila-Fernández A, Nikopoulos K, Riveiro-Alvarez R, Tatu SD, Ayuso C, Rivolta C
PloS one   8(6) e65574   2013   [Refereed]
Age-dependent alteration of intraocular soluble heparan sulfate levels and its implications for proliferative diabetic retinopathy.
Nishiguchi KM, Ushida H, Tomida D, Kachi S, Kondo M, Terasaki H
Molecular vision   19 1125-1131   2013   [Refereed]
Avila-Fernandez A, Corton M, Nishiguchi KM, Muñoz-Sanz N, Benavides-Mori B, Blanco-Kelly F, Riveiro-Alvarez R, Garcia-Sandoval B, Rivolta C, Ayuso C
Ophthalmology   119(12) 2616-2621   Dec 2012   [Refereed]
[Functional regulation of heparin-binding proteins and maintenance of vitreal transparency by intravitreal glucosaminoglycan].
Nishiguchi K
Nippon Ganka Gakkai zasshi   116(11) 1052-1061   Nov 2012   [Refereed]
Nishiguchi KM, Yasuma TR, Tomida D, Nakamura M, Ishikawa K, Kikuchi M, Ohmi Y, Niwa T, Hamajima N, Furukawa K, Terasaki H
Investigative ophthalmology & visual science   53(1) 508-512   Jan 2012   [Refereed]
Nishiguchi KM, Rivolta C
PloS one   7(7) e41902   2012   [Refereed]
Tomida D, Nishiguchi KM, Kataoka K, Yasuma TR, Iwata E, Uetani R, Kachi S, Terasaki H
Investigative ophthalmology & visual science   52(6) 3193-3199   May 2011   [Refereed]
Kataoka K, Nishiguchi KM, Kaneko H, van Rooijen N, Kachi S, Terasaki H
Investigative ophthalmology & visual science   52(3) 1431-1438   Mar 2011   [Refereed]
Elevated C-reactive protein levels and ARMS2/HTRA1 gene variants in subjects without age-related macular degeneration.
Yasuma TR, Nakamura M, Nishiguchi KM, Kikuchi M, Kaneko H, Niwa T, Hamajima N, Terasaki H
Molecular vision   16 2923-2930   Dec 2010   [Refereed]
Nishiguchi KM, Kataoka K, Kachi S, Komeima K, Terasaki H
PloS one   5(10) e13493   Oct 2010   [Refereed]
TRPM1 mutations are associated with the complete form of congenital stationary night blindness.
Nakamura M, Sanuki R, Yasuma TR, Onishi A, Nishiguchi KM, Koike C, Kadowaki M, Kondo M, Miyake Y, Furukawa T
Molecular vision   16 425-437   Mar 2010   [Refereed]
Generation of immature retinal neurons from proliferating cells in the pars plana after retinal histogenesis in mice with retinal degeneration.
Nishiguchi KM, Kaneko H, Nakamura M, Kachi S, Terasaki H
Molecular vision   15 187-199   2009   [Refereed]
Kaneko H, Nishiguchi KM, Nakamura M, Kachi S, Terasaki H
Investigative ophthalmology & visual science   49(9) 4162-4168   Sep 2008   [Refereed]
Kaneko H, Nishiguchi KM, Nakamura M, Kachi S, Terasaki H
Investigative ophthalmology & visual science   49(2) 781-787   Feb 2008   [Refereed]
Nishiguchi KM, Kaneko H, Nakamura M, Kachi S, Terasaki H
Investigative ophthalmology & visual science   49(1) 422-428   Jan 2008   [Refereed]
Nishiguchi KM, Nakamura M, Kaneko H, Kachi S, Terasaki H
Investigative ophthalmology & visual science   48(9) 4315-4320   Sep 2007   [Refereed]
Kanda A, Friedman JS, Nishiguchi KM, Swaroop A
Human mutation   28(6) 589-598   Jun 2007   [Refereed]
Nakamura M, Lin J, Nishiguchi K, Kondo M, Sugita J, Miyake Y
Advances in experimental medicine and biology   572 49-53   2006   [Refereed]
Nishiguchi KM, Sandberg MA, Gorji N, Berson EL, Dryja TP
Human mutation   25(3) 248-258   Mar 2005   [Refereed]
Nishiguchi KM, Friedman JS, Sandberg MA, Swaroop A, Berson EL, Dryja TP
Proceedings of the National Academy of Sciences of the United States of America   101(51) 17819-17824   Dec 2004   [Refereed]
Nishiguchi KM, Sokal I, Yang L, Roychowdhury N, Palczewski K, Berson EL, Dryja TP, Baehr W
Investigative ophthalmology & visual science   45(11) 3863-3870   Nov 2004   [Refereed]
Mutation screening of the phosducin gene PDC in patients with retinitis pigmentosa and allied diseases.
Nishiguchi KM, Berson EL, Dryja TP
Molecular vision   10 62-64   Jan 2004   [Refereed]
Fishman GA, Roberts MF, Derlacki DJ, Grimsby JL, Yamamoto H, Sharon D, Nishiguchi KM, Dryja TP
Archives of ophthalmology (Chicago, Ill. : 1960)   122(1) 70-75   Jan 2004   [Refereed]
Nishiguchi KM, Sandberg MA, Kooijman AC, Martemyanov KA, Pott JW, Hagstrom SA, Arshavsky VY, Berson EL, Dryja TP
Nature   427(6969) 75-78   Jan 2004   [Refereed]