論文

査読有り 筆頭著者 国際誌
2016年

Successful Use of Plasma Exchange in the Treatment of Corticosteroid-Refractory Eosinophilic Granulomatosis with Polyangiitis Associated with Gastrointestinal Manifestations.

Case reports in immunology
  • Kohei Tsujimoto
  • ,
  • Masato Yagita
  • ,
  • Masashi Taniguchi
  • ,
  • Masaaki Fujita

2016
開始ページ
8341751
終了ページ
8341751
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1155/2016/8341751

We describe the case of a 33-year-old woman having corticosteroid-refractory eosinophilic granulomatosis with polyangiitis (EGPA) who presented with abdominal pain and responded dramatically to plasma exchange. Eosinophilia, asthma history, neuropathy, pulmonary infiltrates, and paranasal sinus abnormalities confirmed the diagnosis of EGPA. Treatment was initiated with 1 g/day of methylprednisolone pulse therapy for 3 days followed by 60 mg/day of intravenous prednisolone without relieving abdominal pain. Then, plasma exchange was performed thrice. Abdominal pain disappeared after the first plasma exchange. Indication of plasma exchange for EGPA remains controversial; however, it may represent a valid option in cases with gastrointestinal involvement.

リンク情報
DOI
https://doi.org/10.1155/2016/8341751
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/26989530
PubMed Central
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773532
ID情報
  • DOI : 10.1155/2016/8341751
  • PubMed ID : 26989530
  • PubMed Central 記事ID : PMC4773532

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