2016年
A reversible B-A transition of DNA duplexes induced by synthetic cationic copolymers
CHEMICAL COMMUNICATIONS
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- 巻
- 52
- 号
- 47
- 開始ページ
- 7446
- 終了ページ
- 7449
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1039/c6cc02237e
- 出版者・発行元
- ROYAL SOC CHEMISTRY
Although the B-form duplex is the canonical DNA structure, the A-form duplex plays critical roles in controlling gene expression. Here, reversible B-A transitions of DNA duplexes were induced by synthetic cationic and anionic polymers. Thermodynamic analysis demonstrated that the B-A transition was regulated by the dehydration of the DNA duplex caused by polymer binding.
- リンク情報
- ID情報
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- DOI : 10.1039/c6cc02237e
- ISSN : 1359-7345
- eISSN : 1364-548X
- Web of Science ID : WOS:000378003800003