李欣瑜 (Shin-Yu Lee) - マイポータル

基本情報

所属: 沖縄科学技術大学院大学ヒト進化ゲノミクスユニット Postdoctoral Scholar (Postdoctoral Scholar)

学位: 博士(2019年11月台湾大学医学工程学硏究科)

連絡先: Shinyu.Leeoist.jp
研究者番号: 30910319
J-GLOBAL ID: 202101017279049644
researchmap会員ID: R000020493

研究キーワード

研究分野

経歴

2022年4月 - 現在

沖縄科学技術大学院大学, ヒト進化ゲノミクスユニット, ポスドク研究員 (ポスドク研究員)
2021年4月 - 2022年3月

広島大学, 大学院統合生命科学研究科, 助教 (育成助教)
2021年1月 - 2021年3月

広島大学, 統合生命科学研究科, 研究員

学歴

2013年9月 - 2019年11月

National Taiwan University, Institute of Biomedical Engineering, Ph.D.
2012年9月 - 2013年8月

National Taiwan University, Institute of Biomedical Engineering, Master program
2008年9月 - 2012年6月

National Taiwan University, Department of Animal Science and Technology, Bachelor

受賞

論文

The activity and expression of adenylosuccinate lyase were reduced during modern human evolution, affecting brain and behavior

Xiang-Chun Ju, Shin-Yu Lee, Richard Ågren, Luiz Carlos Machado, Jiawei Xing, Chika Azama, Michael C. Roy, Toshihiro Endo, Wieland Huttner, Adam Siepel …

Proceedings of the National Academy of Sciences 122(32) 2025年8月4日査読有り
Muscle AMP deaminase activity was lower in Neandertals than in modern humans

Dominik Macak, Shin-Yu Lee, Tomas Nyman, Henry Ampah-Korsah, Emilia Strandback, Svante Pääbo, Hugo Zeberg

Nature Communications 16(1) 2025年7月10日査読有り
Platinum(II) Drug-Loaded Gold Nanoshells for Chemo-Photothermal Therapy in Colorectal Cancer

Shin-Yu Lee, Ming-Jium Shieh

ACS APPLIED MATERIALS & INTERFACES 12(4) 4254-4264 2020年1月査読有り
Dual-triggered drug-release vehicles for synergistic cancer therapy

Ting-Yu Tu, Shu-Jyuan Yang, Ming-Hsien Tsai, Chung-Hao Wang, Shin-Yu Lee, Tai-Horng Young, Ming-Jium Shieh

COLLOIDS AND SURFACES B-BIOINTERFACES 173 788-797 2019年1月査読有り
Combined Chemo-Photothermotherapy Using Gold Nanoshells on Drug-Loaded Micellar Templates for Colorectal Cancer Treatment

Shin-Yu Lee, Cheng-Liang Peng, Ming-Jium Shieh

PARTICLE & PARTICLE SYSTEMS CHARACTERIZATION 35(12) 2018年12月査読有り
Morphology of reproductive accessory glands in female Sepia pharaonis (Cephalopoda: Sepiidae) sheds light on egg encapsulation

Jing-Duan Huang, Shin-Yu Lee, Tzu-Yin Chiang, Chung-Cheng Lu, Mong-Fong Lee

JOURNAL OF MORPHOLOGY 279(8) 1120-1131 2018年8月査読有り
Combined photothermo-chemotherapy using gold nanoshells on drug-loaded micelles for colorectal cancer treatment

Shin-Yu Lee, Ming-Jium Shieh

COLLOIDAL NANOPARTICLES FOR BIOMEDICAL APPLICATIONS XIII 10507 2018年査読有り
HSA/PSS Coated Gold Nanorods as Thermo-Triggered Drug Delivery Vehicles for Combined Cancer Photothermal Therapy and Chemotherapy

Ting-Yu Tu, Shu-Jyuan Yang, Chung-Hao Wang, Shin-Yu Lee, Ming-Jium Shieh

OPTICAL METHODS FOR TUMOR TREATMENT AND DETECTION: MECHANISMS AND TECHNIQUES IN PHOTODYNAMIC THERAPY XXVII 10476 2018年査読有り
Prominin-1-Specific Binding Peptide-Modified Apoferritin Nanoparticle Carrying Irinotecan as a Novel Radiosensitizer for Colorectal Cancer Stem-Like Cells

Jenny Ling-Yu Chen, Yuan-Chun Tsai, Ming-Hsien Tsai, Shin-Yu Lee, Ming-Feng Wei, Sung-Hsin Kuo, Ming-Jium Shieh

PARTICLE & PARTICLE SYSTEMS CHARACTERIZATION 34(5) 2017年5月査読有り
Targeting Colorectal Cancer Stem-Like Cells with Anti-CD133 Antibody-Conjugated SN-38 Nanoparticles

Sin-Tzu Ning, Shin-Yu Lee, Ming-Feng Wei, Cheng-Liang Peng, Susan Yun-Fan Lin, Ming-Hsien Tsai, Pei-Chi Lee, Ying-Hsia Shih, Chun-Yen Lin, Tsai-Yueh Luo …

ACS APPLIED MATERIALS & INTERFACES 8(28) 17793-17804 2016年7月査読有り
A theranostic micelleplex co-delivering SN-38 and VEGF siRNA for colorectal cancer therapy

Shin-Yu Lee, Chia-Ying Yang, Cheng-Liang Peng, Ming-Feng Wei, Ke-Cheng Chen, Cheng-Jung Yao, Ming-Jium Shieh

BIOMATERIALS 86 92-105 2016年4月査読有り
In-111-cetuximab as a diagnostic agent by accessible epidermal growth factor (EGF) receptor targeting in human metastatic colorectal carcinoma

Ying-Hsia Shih, Cheng-Liang Peng, Shin-Yu Lee, Ping-Fang Chiang, Cheng-Jung Yao, Wuu-Jyh Lin, Tsai-Yueh Luo, Ming-Jium Shieh

ONCOTARGET 6(18) 16601-16610 2015年6月査読有り
Photothermal cancer therapy via femtosecond-laser-excited FePt nanoparticles

Cheng-Lung Chen, Ling-Ru Kuo, Shin-Yu Lee, Yeu-Kuang Hwu, Shang-Wei Chou, Chia-Chun Chen, Fu-Hsiung Chang, Kung-Hsuan Lin, Dzung-Han Tsai, Yang-Yuan Chen

BIOMATERIALS 34(4) 1128-1134 2013年1月査読有り
In situ real-time investigation of cancer cell photothermolysis mediated by excited gold nanorod surface plasmons

Cheng-Lung Chen, Ling-Ru Kuo, Ching-Lin Chang, Yeu-Kuang Hwu, Cheng-Kuang Huang, Shin-Yu Lee, Kowa Chen, Su-Jien Lin, Jing-Duan Huang, Yang-Yuan Chen

BIOMATERIALS 31(14) 4104-4112 2010年5月査読有り

講演・口頭発表等

Impact of Hominin-specific Genetic Variants on Skeletal Muscle

Shin-Yu Lee

The 30th East Asia Joint Symposium 2024年10月
Impact of Modern Human-specific Genetic Changes in Skeletal Muscle: Insights from a Mouse Model with Humanized ADSL Gene

Lee, S.-Y., Ju, X.-C., Azama, C., Chen, L., Zeberg, H., Pääbo, S.

Human Genetics Asia 2023 2023年10月
工学的手法を用いた筋・腱アッセンブロイドによる筋―腱接合部形成機構の解析

高橋治子, 李欣瑜, 雲山一慧, 郝若麟, 池田皓, 徐銘聡, 永樂元次, 菊池裕

第44回日本分子生物学会年会 2021年12月3日
Dichloro(1,2-diaminocyclohexane) Platinum(II) (DACHPt)-Loaded Gold Nanoshells for Chemo-Photothermotherapy of Colorectal Cancer

S.Y. Lee, M.J. Shieh

the 4th World Congress on Recent Advances in Nanotechnology (RAN’19) International Conference on Nanomedicine, Drug Delivery, and Tissue Engineering (NDDTE'19) 2019年4月
HSA/PSS coated gold nanorods as thermo-triggered drug delivery vehicles for combined cancer photothermal therapy and chemotherapy

T.Y. Tu, S.J. Yang, C.H. Wang, S.Y. Lee, M.J. Shieh

SPIE Photonics West Conference and Exhibition 2018年1月
Combined photothermo-chemotherapy using gold nanoshells on drug-loaded micelles for colorectal cancer treatment

S.Y. Lee, M.J. Shieh

SPIE Photonics West Conference and Exhibition 2018年1月
Gold Nanoshells With Micellar Core for The Delivery of Hydrophobic Chemotherapeutic and Cancer Photothermal Therapy

S.Y. Lee, M.J. Shieh

2016年5月
A Novel Multifunctional Nanomedicine for Magnetic Resonance Imaging and Treatment of Cancer

S.Y. Lee, C.Y. Yang, C.L. Peng, C.J. Yao, P.C. Lee, M.J. Shieh

the 3rd International Conference on Engineering and Applied Sciences 2013年11月

担当経験のある科目(授業)

2021年4月 - 2021年4月

生物科学基礎実験III (広島大学)

共同研究・競争的資金等の研究課題

Impact of Genetic Variations on Muscle Physiology During Hominin Evolution

日本学術振興会科学研究費助成事業若手研究 2024年4月 - 2026年3月

LEE SHINYU
再生医療への応用を見据えた運動器オルガノイドの構築

日本学術振興会外国人特別研究員（一般）(Decline)