論文

査読有り
2007年10月

Peripheral or central administration of nitric oxide synthase inhibitor affects feeding behavior in chicks

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY
  • Md. Sakirul Islam Khan
  • ,
  • Tetsuya Tachibana
  • ,
  • Yuko Hasebe
  • ,
  • Naoto Masuda
  • ,
  • Hiroshi Ueda

148
2
開始ページ
458
終了ページ
462
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1016/j.cbpa.2007.06.006
出版者・発行元
ELSEVIER SCIENCE INC

We investigated the effect of peripheral or central administration of N-G-nitro-L-arginine methyl ester (L-NAME), a nitric oxide (NO) synthase inhibitor, on food intake in layer and broiler chicks (Gallus gallus). The intraperitoneal administration of L-NAME significantly decreased food intake in both broiler and layer chicks while the. administration of D-NAME, an inactive form of L-NAME, had no effect. The intracerebroventricular (ICV) injection of L-NAME did not affect food intake in broiler chicks. However, ICV injection of L-NAME increased food intake in layer chicks while the injection of D-NAME had no effect. In addition to this, L-NAME-induced feeding was negated with the co-injection of L-arginine, suggesting that NO acts as a feeding-inhibitor signal in the brain of layer chicks. The present study revealed that administration of NO synthase inhibitor affected food intake in chicks, but the effect might be changed by chick strain and position of the injection. (C) 2007 Elsevier Inc. All rights reserved.

Web of Science ® 被引用回数 : 20

リンク情報
DOI
https://doi.org/10.1016/j.cbpa.2007.06.006
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/17618151
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000249231400026&DestApp=WOS_CPL
URL
https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=34547608234&origin=inward

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