2014年1月
Low-dose exposure energy-resolved X-ray computed tomography using a contrast agent with a high-energy K-edge
JOURNAL OF NUCLEAR SCIENCE AND TECHNOLOGY
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- 巻
- 51
- 号
- 1
- 開始ページ
- 91
- 終了ページ
- 97
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1080/00223131.2013.849621
- 出版者・発行元
- TAYLOR & FRANCIS LTD
X-ray computed tomography (CT) with iodine contrast agent is widely employed to locate cancers. However, this method has shortcomings such as high-radiation dose exposure, iodine side effects, and a beam hardening effect. We have been working on the energy-resolved CT measurement method using a novel X-ray detection system, the transXend detector, which measures X-rays as electric currents and gives the energy distribution of incident X-rays after analysis. In the present study, we propose a method for low-dose exposure CT that involves the combination of the energy-resolved CT method, which is free from the beam hardening effect, and a harmless contrast agent with high-energy K-edge absorption, such as gold nanoparticles expected as a future contrast agent. Comparisons of radiation dose exposures as functions of aluminum filter thickness at the exit aperture of an X-ray tube and the K-edge energies of contrast agents are described.
- リンク情報
- ID情報
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- DOI : 10.1080/00223131.2013.849621
- ISSN : 0022-3131
- eISSN : 1881-1248
- Web of Science ID : WOS:000327187500008