Makoto Takeo

Profile Information

Affiliation: Associate professor, Medical Institute of Bioregulation, Kyushu University

Contact information: makoto.takeobioreg.kyushu-u.ac.jp
Researcher number: 50782116
ORCID iD: https://orcid.org/0000-0002-5597-5994
J-GLOBAL ID: 202201013633115538
researchmap Member ID: R000038294

External link: https://www.aikosada.com/

Research Interests

Research Areas

Research History

Jan, 2024 - Present

Medical Institute of Bioregulation Department of Molecular and Cellular Biology, Kyushu University
Dec, 2019 - Dec, 2023

RIKEN
Apr, 2016 - Nov, 2018

RIKEN
Dec, 2008 - Mar, 2016

The Ronald O. Perelman Department of Dermatology, New York University School of Medicine

Education

Apr, 2003 - Sep, 2008

Hokkaido University
Apr, 2001 - Mar, 2003

Hokkaido University
Apr, 1997 - Mar, 2001

Hirosaki University

Papers

Comparative studies of hair shaft components between healthy and diseased donors.

Atsuko Ota, Hiroaki Kitamura, Keigo Sugimoto, Miho Ogawa, Naoshi Dohmae, Hiroki Okuno, Kazuya Takahashi, Kazutaka Ikeda, Tsutomu Tomita, Naoki Matsuoka …

PloS one, 19(5) e0301092, 2024
Cyclical dermal micro-niche switching governs the morphological infradian rhythm of mouse zigzag hair.

Makoto Takeo, Koh-Ei Toyoshima, Riho Fujimoto, Tomoyo Iga, Miki Takase, Miho Ogawa, Takashi Tsuji

Nature communications, 14(1) 4478-4478, Aug 4, 2023
Dedifferentiation maintains melanocyte stem cells in a dynamic niche

Qi Sun, Wendy Lee, Hai Hu, Tatsuya Ogawa, Sophie De Leon, Ioanna Katehis, Chae Ho Lim, Makoto Takeo, Michael Cammer, M. Mark Taketo …

Nature, Apr 27, 2023
Mechanical homeostasis of liver sinusoid is involved in the initiation and termination of liver regeneration.

Jun Ishikawa, Makoto Takeo, Ayako Iwadate, Junko Koya, Miho Kihira, Masamitsu Oshima, Yuki Suzuki, Kazushi Taniguchi, Ayaka Kobayashi, Takashi Tsuji

Communications biology, 4(1) 409-409, Apr 7, 2021
Expansion and characterization of epithelial stem cells with potential for cyclical hair regeneration.

Makoto Takeo, Kyosuke Asakawa, Koh-Ei Toyoshima, Miho Ogawa, JingJing Tong, Tarou Irié, Masayuki Yanagisawa, Akio Sato, Takashi Tsuji

Scientific reports, 11(1) 1173-1173, Feb 10, 2021
ケロイドにおける神経関連タンパクの発現

松添晴加, 池田実香, 内藤素子, 片岡和哉, 川端智也, 岡俊吾, 武尾真, 辻孝

日本形成外科学会基礎学術集会プログラム・抄録集, 30th, 2021
ケロイドモデル動物の構築(第3報)

池田実香, 松添晴加, 内藤素子, 片岡和哉, 川端智也, 岡俊吾, 辻孝, 武尾真

日本形成外科学会基礎学術集会プログラム・抄録集, 30th, 2021
Tissue-scale tensional homeostasis in skin regulates structure and physiological function.

Shun Kimura, Ayako Tsuchiya, Miho Ogawa, Miki Ono, Nao Suda, Kaori Sekimoto, Makoto Takeo, Takashi Tsuji

Communications biology, 3(1) 637-637, Oct 30, 2020
OPN4 belongs to the photosensitive system of the human skin.

Junya Kusumoto, Makoto Takeo, Kazunobu Hashikawa, Takahide Komori, Takashi Tsuji, Hiroto Terashi, Shunsuke Sakakibara

Genes to cells : devoted to molecular & cellular mechanisms, 25(3) 215-225, Mar, 2020
成体マウスにおける持続的な毛周期に必要な毛包幹細胞の同定

武尾真, 浅川杏祐, 小川美帆, 小川美帆, 童菁菁, 柳澤正之, 佐藤明男, 辻孝, 辻孝, 辻孝 …

日本再生医療学会総会(Web), 19th, 2020
A novel mouse model demonstrates that oncogenic melanocyte stem cells engender melanoma resembling human disease.

Qi Sun, Wendy Lee, Yasuaki Mohri, Makoto Takeo, Chae Ho Lim, Xiaowei Xu, Peggy Myung, Radhika P Atit, M Mark Taketo, Rana S Moubarak …

Nature communications, 10(1) 5023-5023, Nov 4, 2019
Functional ectodermal organ regeneration as the next generation of organ replacement therapy.

Etsuko Ikeda, Miho Ogawa, Makoto Takeo, Takashi Tsuji

Open biology, 9(3) 190010-190010, Mar 29, 2019
再生医療up to date【多次元構造臓器の再生】次世代器官再生医療としての毛包再生医療の実現に向けて

武尾真, 小川美帆, 小川美帆, 岡本尚一, 辻孝, 辻孝

腎と透析, 86(3), 2019
成体マウスZigzag毛の変曲点における細胞動態解析

藤本理歩, 藤本理歩, 武尾真, 伊賀朋世, 辻孝, 辻孝, 辻孝

日本分子生物学会年会プログラム・要旨集(Web), 42nd, 2019
ケロイド移植モデルの構築(第2報)

池田実香, 松添晴加, 内藤素子, 片岡和哉, 川端智也, 辻孝, 武尾真

日本形成外科学会基礎学術集会プログラム・抄録集, 28th, 2019
成体マウスにおける持続的な毛周期に必要な毛包幹細胞の同定

武尾真, 浅川杏祐, 小川美帆, 小川美帆, 童菁菁, 童菁菁, 辻孝, 辻孝, 辻孝

日本分子生物学会年会プログラム・要旨集(Web), 42nd, 2019
マウス毛包上皮性幹細胞の器官誘導能を制御する培養方法の確立

童菁菁, 童菁菁, 武尾真, 浅川杏祐, 小川美帆, 小川美帆, 辻孝, 辻孝, 辻孝

日本分子生物学会年会プログラム・要旨集(Web), 42nd, 2019
Hedgehog stimulates hair follicle neogenesis by creating inductive dermis during murine skin wound healing.

Chae Ho Lim, Qi Sun, Karan Ratti, Soung-Hoon Lee, Ying Zheng, Makoto Takeo, Wendy Lee, Piul Rabbani, Maksim V Plikus, Jason E Cain …

Nature communications, 9(1) 4903-4903, Nov 21, 2018
Organ regeneration based on developmental biology: past and future.

Makoto Takeo, Takashi Tsuji

Current opinion in genetics & development, 52 42-47, Oct, 2018
Dissecting Wnt Signaling for Melanocyte Regulation during Wound Healing.

Qi Sun, Piul Rabbani, Makoto Takeo, Soung-Hoon Lee, Chae Ho Lim, En-Nekema Shandi Noel, M Mark Taketo, Peggy Myung, Sarah Millar, Mayumi Ito

The Journal of investigative dermatology, 138(7) 1591-1600, Jul, 2018

Misc.

男性型・女性型脱毛症の治療とケア-現状と未来-III-3 再生医療周期的な毛包を再生させる幹細胞の増幅と特定

武尾真, 辻孝

美容皮膚医学Beauty, 5(3), 2022
Development of regenerative skin organ system with skin appendages

コスメトロジー研究報告, 29 135-140, 2021
毛髪を"種"から再生する未来の再生医療

小川美帆, 武尾真, 岡本尚一, 辻孝

現代化学, (577) 26-29, Apr, 2019
Coordinated Activation of Wnt in Epithelial and Melanocyte Stem Cells Induces Pigmented Hair Regeneration

細胞工学, 32(4) 430-434, 2013
いきものの不思議ヤマトヒメミミズ--小さな体にひそむ多くの不思議

武尾真

生物の科学遺伝, 63(1) 8-11, Jan, 2009
ISOLATION AND ANALYSIS OF GENES EXPRESSED IN EARLY REGENERATION STAGES OF ENCHYTRAEUS JAPONENSIS(Developmental Biology)(Proceedings of the Seventy-Third Annual Meeting of the Zoological Society of Japan) :

Takeo Makoto, Yoshida-Noro Chikako, Tochinai Shin

Zoological science, 19(12) 1454-1454, 2002

Research Projects

器官再生の起点となる傷上皮形成機構の解明と応用

科学研究費助成事業, 基盤研究(B), 日本学術振興会, Apr, 2025 - Mar, 2028

武尾真
器官再生の起点となる傷上皮形成機構の解明と応用

2024年度内藤記念科学奨励金・研究助成, 公益財団法人内藤記念科学振興財団, Dec, 2024 - Dec, 2025
keloidal spheroidとシュワン細胞からなるケロイドモデルの作成

科学研究費助成事業, 基盤研究(C), 日本学術振興会, Apr, 2022 - Mar, 2025

池田実香, 片岡和哉, 川端智也, 内藤素子, 辻孝, 武尾真
Identification of new mechanism of morphological rhythm generated by niche switching

Ohsumi Frontier Science Foundation, Oct, 2022 - Sep, 2024
三次元器官の生体外構築を目指した哺乳類成体器官における形態形成メカニズムの解明

科学研究費助成事業基盤研究(C), 基盤研究(C), 日本学術振興会, Apr, 2021 - Mar, 2024

武尾真, 辻孝
Development of innovative technologies towered organ regeneration by control of organ fate

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (A), Grant-in-Aid for Scientific Research (A), Japan Society for the Promotion of Science, Apr, 2019 - Mar, 2022

Tsuji Takashi
Identification of organ-inductive potential nail mesenchymal cell and development of fundamental method for nail organ regeneration

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C), Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2018 - Mar, 2021

Takeo Makoto
マウス体毛の周期的形態変化を生み出す細胞動態の解明

研究助成金, 公益財団法人小柳財団, Apr, 2020 - Mar, 2021
皮膚付属器官を有する三次元再生皮膚器官系の開発

ライフサイエンス研究助成, 公益財団法人武田科学振興財団, Apr, 2019 - Mar, 2021
指・四肢再生技術開発に向けた概念実証研究

神戸医療産業都市研究開発助成金, Apr, 2018 - Mar, 2021
皮膚付属器官を有する三次元再生皮膚器官系の開発

コスメトロジー研究助成, 公益財団法人コーセーコスメトロジー研究財団, Apr, 2019 - Mar, 2020
器官誘導能をもつ毛包幹細胞の同定をその誘導メカニズムの解明

内藤記念科学研究助成, 公益財団法人内藤記念科学振興財団, Apr, 2018 - Mar, 2020
Development of bio-skin, an innovative three-dimensional skin evaluation model with skin appendages

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (A), Grant-in-Aid for Scientific Research (A), Japan Society for the Promotion of Science, Apr, 2016 - Mar, 2019

Tsuji Takashi
Identification of organ inductive hair follicle stem cells and its regulation mechanism

Grants-in-Aid for Scientific Research Grant-in-Aid for Research Activity Start-up, Grant-in-Aid for Research Activity Start-up, Japan Society for the Promotion of Science, Aug, 2016 - Mar, 2018

Takeo Makoto

Industrial Property Rights

WO2020-066818 毛包上皮性幹細胞の生体外増殖方法

辻孝, 浅川杏祐, 武尾真, 豊島公栄, 小川美帆, 森悠, 岸本恭介

Profile Information

Research Interests

Research Areas

Research History

Education

Papers

Misc.

Research Projects

Industrial Property Rights

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