論文

査読有り
1992年3月

DEGENERATION OF MOTOR-NERVE FIBERS ENHANCES THE EXPRESSION OF CALCITONIN GENE-RELATED PEPTIDE IN RAT SENSORY NEURONS

NEUROSCIENCE LETTERS
  • M SAKAGUCHI
  • ,
  • Y INAISHI
  • ,
  • Y KASHIHARA
  • ,
  • M KUNO

137
1
開始ページ
61
終了ページ
64
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1016/0304-3940(92)90298-L
出版者・発行元
ELSEVIER SCI IRELAND LTD

Calcitonin gene-related peptide (CGRP) in skeletal muscle is of neural origin. After degeneration of sensory fibers induced by removal of the lumbar dorsal root ganglia (DRG), the CGRP content in the rat soleus muscle was reduced to about 5% of the normal level. In contrast, degeneration of motor fibers induced by sectioning of the lumbar ventral roots markedly increased the CGRP content in the soleus muscle and CGRP levels in the lumbar DRG. It is suggested that the expression of CGRP in sensory neurons is up-regulated by some humoral factor induced by degeneration of motor nerve fibers.


リンク情報
DOI
https://doi.org/10.1016/0304-3940(92)90298-L
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/1625819
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:A1992HL20200015&DestApp=WOS_CPL

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