大杉満 (OHSUGI MITSURU) - マイポータル

Design of and rationale for the Japan Diabetes compREhensive database project based on an Advanced electronic Medical record System (J-DREAMS)

Takehiro Sugiyama, Kengo Miyo, Tetsuro Tsujimoto, Ryota Kominami, Hiroshi Ohtsu, Mitsuru Ohsugi, Kayo Waki, Takashi Noguchi, Kazuhiko Ohe, Takashi Kadowaki …

Diabetology International 8(4) 375-382 2017年11月1日査読有り

Efficacy and safety of sitagliptin as compared with glimepiride in Japanese patients with type 2 diabetes mellitus aged ≥ 60 years (START-J trial).

Terauchi Y, Yamada Y, Ishida H, Ohsugi M, Kitaoka M, Satoh J, Yabe D, Shihara N, Seino Y

Diabetes, obesity & metabolism 19(8) 1188-1192 2017年8月査読有り

Ethnic differences in insulin sensitivity, β-cell function, and hepatic extraction between Japanese and Caucasians: a minimal model analysis.

Møller JB, Dalla Man C, Overgaard RV, Ingwersen SH, Tornøe CW, Pedersen M, Tanaka H, Ohsugi M, Ueki K, Lynge J …

The Journal of clinical endocrinology and metabolism 99(11) 4273-4280 2014年11月査読有り

Deregulation of pancreas-specific oxidoreductin ERO1β in the pathogenesis of diabetes mellitus.

Awazawa M, Futami T, Sakada M, Kaneko K, Ohsugi M, Nakaya K, Terai A, Suzuki R, Koike M, Uchiyama Y …

Molecular and cellular biology 34(7) 1290-1299 2014年4月査読有り

Body Composition Is the Main Determinant for the Difference in Type 2 Diabetes Pathophysiology Between Japanese and Caucasians

Jonas B. Moller, Maria Pedersen, Haruhiko Tanaka, Mitsuru Ohsugi, Rune V. Overgaard, Jan Lynge, Katrine Almind, Nina-Maria Vasconcelos, Pernille Poulsen, Charlotte Keller …

DIABETES CARE 37(3) 796-804 2014年3月査読有り

Saturated fatty acid and TLR signaling link β cell dysfunction and islet inflammation.

Eguchi K, Manabe I, Oishi-Tanaka Y, Ohsugi M, Kono N, Ogata F, Yagi N, Ohto U, Kimoto M, Miyake K …

Cell metabolism 15(4) 518-533 2012年4月査読有り

Impact of Diabetes Among Revascularized Patients in Japan and the US

Shun Kohsaka, Masashi Goto, Toshiyuki Nagai, Vei-Vei Lee, MacArthur Elayda, Yutaka Furukawa, Masanori Fukushima, Masashi Komeda, Ryuzo Sakata, Mitsuru Ohsugi …

DIABETES CARE 35(3) 654-659 2012年3月査読有り

The effectiveness of liraglutide in nonalcoholic fatty liver disease patients with type 2 diabetes mellitus compared to sitagliptin and pioglitazone.

Ohki T, Isogawa A, Iwamoto M, Ohsugi M, Yoshida H, Toda N, Tagawa K, Omata M, Koike K

TheScientificWorldJournal 2012 496453 2012年査読有り

[Emerging GLP-1 analogues and dipeptidyl peptidase 4(DPP-4) inhibitors].

Ohsugi M

Nihon rinsho. Japanese journal of clinical medicine 69(5) 895-901 2011年5月査読有り

Blockade of class IB phosphoinositide-3 kinase ameliorates obesity-induced inflammation and insulin resistance

Naoki Kobayashi, Kohjiro Ueki, Yukiko Okazaki, Aya Iwane, Naoto Kubota, Mitsuru Ohsugi, Motoharu Awazawa, Masatoshi Kobayashi, Takayoshi Sasako, Kazuma Kaneko …

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 108(14) 5753-5758 2011年4月査読有り

Adiponectin Enhances Insulin Sensitivity by Increasing Hepatic IRS-2 Expression via a Macrophage-Derived IL-6-Dependent Pathway

Motoharu Awazawa, Kohjiro Ueki, Kazunori Inabe, Toshimasa Yamauchi, Naoto Kubota, Kazuma Kaneko, Masatoshi Kobayashi, Aya Iwane, Takayoshi Sasako, Yukiko Okazaki …

CELL METABOLISM 13(4) 401-412 2011年4月査読有り

Class IA phosphatidylinositol 3-kinase in pancreatic β cells controls insulin secretion by multiple mechanisms.

Kaneko K, Ueki K, Takahashi N, Hashimoto S, Okamoto M, Awazawa M, Okazaki Y, Ohsugi M, Inabe K, Umehara T …

Cell metabolism 12(6) 619-632 2010年12月査読有り

Decreased Insulin Secretion and Accumulation of Triglyceride in beta Cells Overexpressing a Dominant-negative Form of AMP-activated Protein Kinase

Yukiko Okazaki, Kazuhiro Eto, Tokuyuki Yamashita, Masayuki Okamoto, Mitsuru Ohsugi, Mitsuhiko Noda, Yasuo Terauchi, Kohjiro Ueki, Takashi Kadowaki

ENDOCRINE JOURNAL 57(2) 141-152 2010年2月査読有り

CD8(+) effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity

Satoshi Nishimura, Ichiro Manabe, Mika Nagasaki, Koji Eto, Hiroshi Yamashita, Mitsuru Ohsugi, Makoto Otsu, Kazuo Hara, Kohjiro Ueki, Seiryo Sugiura …

NATURE MEDICINE 15(8) 914-U116 2009年8月査読有り

Rimonabant Ameliorates Insulin Resistance via both Adiponectin-dependent and Adiponectin-independent Pathways

Taku Watanabe, Naoto Kubota, Mitsuru Ohsugi, Tetsuya Kubota, Iseki Takamoto, Masato Iwabu, Motoharu Awazawa, Hisayuki Katsuyama, Chiaki Hasegawa, Kumpei Tokuyama …

JOURNAL OF BIOLOGICAL CHEMISTRY 284(3) 1803-1812 2009年1月査読有り

Dynamic functional relay between insulin receptor substrate 1 and 2 in hepatic insulin signaling during fasting and feeding

Naoto Kubota, Tetsuya Kubota, Shinsuke Itoh, Hiroki Kumagai, Hideki Kozono, Iseki Takamoto, Tomoka Mineyama, Hitomi Ogata, Kumpei Tokuyama, Mitsuru Ohsugi …

CELL METABOLISM 8(1) 49-64 2008年7月査読有り

An efficient reproductive method for Irs2(-/-) mice with C57BL/6JJcl genetic background

Haruo Hashimoto, Tomoo Eto, Tsutomu Kamisako, Naoko Hoya, Teruhiko Hatakeyama, Toshiro Arai, Makoto Yokosuka, Yasuyuki Ohnishi, Mamoru Ito, Kyoji Hioki …

EXPERIMENTAL ANIMALS 57(4) 407-411 2008年7月査読有り

SUMOylation of Krüppel-like transcription factor 5 acts as a molecular switch in transcriptional programs of lipid metabolism involving PPAR-delta.

Oishi Y, Manabe I, Tobe K, Ohsugi M, Kubota T, Fujiu K, Maemura K, Kubota N, Kadowaki T, Nagai R

Nature medicine 14(6) 656-666 2008年6月査読有り

In vivo imaging in mice reveals local cell dynamics and inflammation in obese adipose tissue

Satoshi Nishimura, Ichiro Manabe, Mika Nagasaki, Kinya Seo, Hiroshi Yamashita, Yumiko Hosoya, Mitsuru Ohsugi, Kazuyuki Tobe, Takashi Kadowaki, Ryozo Nagai …

JOURNAL OF CLINICAL INVESTIGATION 118(2) 710-721 2008年2月査読有り

A global approach to identify differentially expressed genes in cDNA (two-color) microarray experiments

Yiyong Zhou, Corentin Cras-Meneur, Mitsuru Ohsugi, Gary D. Stormo, M. Alan. Permutt

BIOINFORMATICS 23(16) 2073-2079 2007年8月査読有り

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