論文

査読有り
2017年3月

Reductive ipso-radical cyclization onto aromatic rings of five-membered alicyclic amino acids bearing N-(2-phenyl)benzoyl groups by photoinduced electron transfer promoted decarboxylation

TETRAHEDRON LETTERS
  • Tomoaki Yamada
  • ,
  • Yui Ozaki
  • ,
  • Mugen Yamawaki
  • ,
  • Yoshihiko Sugiura
  • ,
  • Kana Nishino
  • ,
  • Toshio Morita
  • ,
  • Yasuharu Yoshimi

58
9
開始ページ
835
終了ページ
838
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1016/j.tetlet.2017.01.038
出版者・発行元
PERGAMON-ELSEVIER SCIENCE LTD

A new radical cyclization has been developed for the one-step synthesis of spiro dihydroisoquinolinone derivatives from alicyclic amino acids bearing N-(2-phenyl)benzoyl groups through photoinduced electron transfer (PET)-promoted decarboxylation. Reductive ipso-radical cyclization onto a benzene ring by an alkyl radical is achieved under mild conditions for the first time, although the substrates are limited to five-membered aliphatic carboxylic acids bearing N-(2-phenyl)benzoyl groups. (C) 2017 Elsevier Ltd. All rights reserved.

リンク情報
DOI
https://doi.org/10.1016/j.tetlet.2017.01.038
ID情報
  • DOI : 10.1016/j.tetlet.2017.01.038

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