越川 直彦

J-GLOBALへ         更新日: 18/10/11 13:46
 
アバター
研究者氏名
越川 直彦
 
コシカワ ナオヒコ
所属
地方独立行政法人神奈川県立病院機構神奈川県立がんセンター(臨床研究所)
部署
臨床研究所
職名
部長
科研費研究者番号
70334282

研究分野

 
 

受賞

 
2005年9月
日本癌学会 研究奨励賞
 
2000年6月
日本がん転移学会 研究奨励賞
 

論文

 
Takahashi Y, Hamasaki M, Aoki M, Koga K, Koshikawa N, Miyamoto S, Nabeshima K
Anticancer research   38(7) 4257-4266   2018年7月   [査読有り]
Suzuki T, Minerva D, Nishiyama K, Koshikawa N, Chaplain MAJ
Cancer science   109(1) 15-23   2018年1月   [査読有り]
Kikuchi K, Kozuka-Hata H, Oyama M, Seiki M, Koshikawa N
Methods in molecular biology (Clifton, N.J.)   1731 29-37   2018年   [査読有り]
Koshikawa N, Minegishi T, Kiyokawa H, Seiki M
Cell death & disease   8(10) e3134   2017年10月   [査読有り]
Kiyokawa H, Yasuda H, Oikawa R, Okuse C, Matsumoto N, Ikeda H, Watanabe T, Yamamoto H, Itoh F, Otsubo T, Yoshimura T, Yoshida E, Nakagawa M, Koshikawa N, Seiki M
Cancer science   108(7) 1432-1439   2017年7月   [査読有り]
Nakagawa M, Karashima T, Kamada M, Yoshida E, Yoshimura T, Nojima M, Inoue K, Shuin T, Seiki M, Koshikawa N
Biomarker research   5 29   2017年   [査読有り]
Tatsukawa R, Koga K, Aoki M, Koshikawa N, Imafuku S, Nakayama J, Nabeshima K
Virchows Archiv : an international journal of pathology   469(1) 25-34   2016年7月   [査読有り]
Otani S, Kakinuma S, Kamiya A, Goto F, Kaneko S, Miyoshi M, Tsunoda T, Asano Y, Kawai-Kitahata F, Nitta S, Nakata T, Okamoto R, Itsui Y, Nakagawa M, Azuma S, Asahina Y, Yamaguchi T, Koshikawa N, Seiki M, Nakauchi H, Watanabe M
Biochemical and biophysical research communications   469(4) 1062-1068   2016年1月   [査読有り]
Kamada M, Koshikawa N, Minegishi T, Kawada C, Karashima T, Shuin T, Seiki M
Cancer science   106(12) 1730-1737   2015年12月   [査読有り]
Koshikawa N
Nihon yakurigaku zasshi. Folia pharmacologica Japonica   146(5) 248-251   2015年11月   [査読有り]
Kikuchi K, Noguchi A, Kasajima R, Miyagi Y, Hoshino D, Koshikawa N, Kubota A, Yokose T, Takano Y
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine   36(10) 7865-7872   2015年9月   [査読有り]
Koshikawa N, Hoshino D, Taniguchi H, Minegishi T, Tomari T, Nam SO, Aoki M, Sueta T, Nakagawa T, Miyamoto S, Nabeshima K, Weaver AM, Seiki M
Cancer research   75(16) 3327-3339   2015年8月   [査読有り]
Hoshino D, Nagano M, Saitoh A, Koshikawa N, Suzuki T, Seiki M
PloS one   8(1) e50825   2013年   [査読有り]
Watanabe A, Hoshino D, Koshikawa N, Seiki M, Suzuki T, Ichikawa K
PLoS computational biology   9(5) e1003086   2013年   [査読有り]
[Prevention of tumour invasion].
Hoshino D, Koshikawa N, Seiki M, Taniguchi H
Nihon rinsho. Japanese journal of clinical medicine   70 Suppl 8 154-158   2012年11月   [査読有り]
Uematsu T, Konishi C, Hoshino D, Han X, Tomari T, Egawa N, Takada Y, Isobe T, Seiki M, Koshikawa N
Journal of cellular physiology   227(8) 3072-3079   2012年8月   [査読有り]
Saitou T, Itano K, Hoshino D, Koshikawa N, Seiki M, Ichikawa K, Suzuki T
Theoretical biology & medical modelling   9 33   2012年8月   [査読有り]
Nishida C, Kusubata K, Tashiro Y, Gritli I, Sato A, Ohki-Koizumi M, Morita Y, Nagano M, Sakamoto T, Koshikawa N, Kuchimaru T, Kizaka-Kondoh S, Seiki M, Nakauchi H, Heissig B, Hattori K
Blood   119(23) 5405-5416   2012年6月   [査読有り]
Saitou T, Rouzimaimaiti M, Koshikawa N, Seiki M, Ichikawa K, Suzuki T
Journal of theoretical biology   298 138-146   2012年4月   [査読有り]
Nagano M, Hoshino D, Koshikawa N, Akizawa T, Seiki M
International journal of cell biology   2012 310616   2012年   [査読有り]
Shuo T, Koshikawa N, Hoshino D, Minegishi T, Ao-Kondo H, Oyama M, Sekiya S, Iwamoto S, Tanaka K, Seiki M
PloS one   7(8) e43751   2012年   [査読有り]
Nagano M, Hoshino D, Koshiba S, Shuo T, Koshikawa N, Tomizawa T, Hayashi F, Tochio N, Harada T, Akizawa T, Watanabe S, Handa N, Shirouzu M, Kigawa T, Yokoyama S, Seiki M
The Journal of biological chemistry   286(36) 31598-31609   2011年9月   [査読有り]
Hamasaki H, Koga K, Aoki M, Hamasaki M, Koshikawa N, Seiki M, Iwasaki H, Nakayama J, Nabeshima K
British journal of cancer   105(6) 824-832   2011年9月   [査読有り]
Onozuka I, Kakinuma S, Kamiya A, Miyoshi M, Sakamoto N, Kiyohashi K, Watanabe T, Funaoka Y, Ueyama M, Nakagawa M, Koshikawa N, Seiki M, Nakauchi H, Watanabe M
Biochemical and biophysical research communications   406(1) 134-140   2011年3月   [査読有り]
Srichai MB, Colleta H, Gewin L, Matrisian L, Abel TW, Koshikawa N, Seiki M, Pozzi A, Harris RC, Zent R
PloS one   6(2) e17099   2011年2月   [査読有り]
Nagano M, Hoshino D, Sakamoto T, Akizawa T, Koshikawa N, Seiki M
Cell adhesion & migration   5(1) 23-28   2011年1月   [査読有り]
Koshikawa N, Mizushima H, Minegishi T, Eguchi F, Yotsumoto F, Nabeshima K, Miyamoto S, Mekada E, Seiki M
Cancer science   102(1) 111-116   2011年1月   [査読有り]
Hoshino D, Koshikawa N, Seiki M
The Journal of biological chemistry   286(4) 3139-3148   2011年1月   [査読有り]
Riggins KS, Mernaugh G, Su Y, Quaranta V, Koshikawa N, Seiki M, Pozzi A, Zent R
Experimental cell research   316(17) 2993-3005   2010年10月   [査読有り]
Nagano M, Hoshino D, Sakamoto T, Kawasaki N, Koshikawa N, Seiki M
The Journal of biological chemistry   285(27) 21013-21022   2010年7月   [査読有り]
Koshikawa N, Mizushima H, Minegishi T, Iwamoto R, Mekada E, Seiki M
Cancer research   70(14) 6093-6103   2010年7月   [査読有り]
Hoshino D, Tomari T, Nagano M, Koshikawa N, Seiki M
The Journal of biological chemistry   284(40) 27315-27326   2009年10月   [査読有り]
Niiya D, Egawa N, Sakamoto T, Kikkawa Y, Shinkawa T, Isobe T, Koshikawa N, Seiki M
The Journal of biological chemistry   284(40) 27360-27369   2009年10月   [査読有り]
Tomari T, Koshikawa N, Uematsu T, Shinkawa T, Hoshino D, Egawa N, Isobe T, Seiki M
Cancer science   100(7) 1284-1290   2009年7月   [査読有り]
Koshikawa N, Minegishi T, Nabeshima K, Seiki M
Cancer research   68(2) 530-536   2008年1月   [査読有り]
Egawa N, Koshikawa N, Tomari T, Nabeshima K, Isobe T, Seiki M
The Journal of biological chemistry   281(49) 37576-37585   2006年12月   [査読有り]
Koshikawa N, Minegishi T, Sharabi A, Quaranta V, Seiki M
The Journal of biological chemistry   280(1) 88-93   2005年1月   [査読有り]
Koshikawa N, Schenk S, Moeckel G, Sharabi A, Miyazaki K, Gardner H, Zent R, Quaranta V
FASEB journal : official publication of the Federation of American Societies for Experimental Biology   18(2) 364-366   2004年2月   [査読有り]
Kioi M, Yamamoto K, Higashi S, Koshikawa N, Fujita K, Miyazaki K
Oncogene   22(54) 8662-8670   2003年11月   [査読有り]
Takino T, Koshikawa N, Miyamori H, Tanaka M, Sasaki T, Okada Y, Seiki M, Sato H
Oncogene   22(30) 4617-4626   2003年7月   [査読有り]
Seiki M, Koshikawa N, Yana I
Cancer metastasis reviews   22(2-3) 129-143   2003年6月   [査読有り]
Pirilä E, Sharabi A, Salo T, Quaranta V, Tu H, Heljasvaara R, Koshikawa N, Sorsa T, Maisi P
Biochemical and biophysical research communications   303(4) 1012-1017   2003年4月   [査読有り]
Schenk S, Hintermann E, Bilban M, Koshikawa N, Hojilla C, Khokha R, Quaranta V
The Journal of cell biology   161(1) 197-209   2003年4月   [査読有り]
Mori H, Tomari T, Koshikawa N, Kajita M, Itoh Y, Sato H, Tojo H, Yana I, Seiki M
The EMBO journal   21(15) 3949-3959   2002年8月   [査読有り]
Fusa K, Saigusa T, Koshikawa N, Cools AR
European journal of pharmacology   448(2-3) 143-150   2002年7月   [査読有り]
Zent R, Bush KT, Pohl ML, Quaranta V, Koshikawa N, Wang Z, Kreidberg JA, Sakurai H, Stuart RO, Nigám SK
Developmental biology   238(2) 289-302   2001年10月   [査読有り]
Cooperative interactions of laminin 5 gamma2 chain, matrix metalloproteinase-2, and membrane type-1-matrix/metalloproteinase are required for mimicry of embryonic vasculogenesis by aggressive melanoma.
Seftor RE, Seftor EA, Koshikawa N, Meltzer PS, Gardner LM, Bilban M, Stetler-Stevenson WG, Quaranta V, Hendrix MJ
Cancer research   61(17) 6322-6327   2001年9月   [査読有り]
Shang M, Koshikawa N, Schenk S, Quaranta V
The Journal of biological chemistry   276(35) 33045-33053   2001年8月   [査読有り]
Sole expression of laminin gamma 2 chain in invading tumor cells and its association with stromal fibrosis in lung adenocarcinomas.
Kagesato Y, Mizushima H, Koshikawa N, Kitamura H, Hayashi H, Ogawa N, Tsukuda M, Miyazaki K
Japanese journal of cancer research : Gann   92(2) 184-192   2001年2月   [査読有り]
Marked increase of trypsin(ogen) in serum of linitis plastica (gastric cancer, borrmann 4) patients.
Ichikawa Y, Koshikawa N, Hasegawa S, Ishikawa T, Momiyama N, Kunizaki C, Takahashi M, Moriwaki Y, Akiyama H, Yamaoka H, Yanoma S, Tsuburaya A, Nagashima Y, Shimada H, Miyazaki K
Clinical cancer research : an official journal of the American Association for Cancer Research   6(4) 1385-1388   2000年4月   [査読有り]
Koshikawa N, Giannelli G, Cirulli V, Miyazaki K, Quaranta V
The Journal of cell biology   148(3) 615-624   2000年2月   [査読有り]
Trypsin stimulates integrin alpha(5)beta(1)-dependent adhesion to fibronectin and proliferation of human gastric carcinoma cells through activation of proteinase-activated receptor-2.
Miyata S, Koshikawa N, Yasumitsu H, Miyazaki K
The Journal of biological chemistry   275(7) 4592-4598   2000年2月   [査読有り]
Overexpression of laminin gamma2 chain monomer in invading gastric carcinoma cells.
Koshikawa N, Moriyama K, Takamura H, Mizushima H, Nagashima Y, Yanoma S, Miyazaki K
Cancer research   59(21) 5596-5601   1999年11月   [査読有り]
Expression of trypsin in human cancer cell lines and cancer tissues and its tight binding to soluble form of Alzheimer amyloid precursor protein in culture.
Miyata S, Koshikawa N, Higashi S, Miyagi Y, Nagashima Y, Yanoma S, Kato Y, Yasumitsu H, Miyazaki K
Journal of biochemistry   125(6) 1067-1076   1999年6月   [査読有り]
Matrilysin as a target for chemotherapy for colon cancer: use of antisense oligonucleotides as antimetastatic agents.
Miyazaki K, Koshikawa N, Hasegawa S, Momiyama N, Nagashima Y, Moriyama K, Ichikawa Y, Ishikawa T, Mitsuhashi M, Shimada H
Cancer chemotherapy and pharmacology   43 Suppl S52-5   1999年   [査読有り]
Miyata S, Miyagi Y, Koshikawa N, Nagashima Y, Kato Y, Yasumitsu H, Hirahara F, Misugi K, Miyazaki K
Clinical & experimental metastasis   16(7) 613-622   1998年10月   [査読有り]
Koshikawa N, Hasegawa S, Nagashima Y, Mitsuhashi K, Tsubota Y, Miyata S, Miyagi Y, Yasumitsu H, Miyazaki K
The American journal of pathology   153(3) 937-944   1998年9月   [査読有り]
Hasegawa S, Koshikawa N, Momiyama N, Moriyama K, Ichikawa Y, Ishikawa T, Mitsuhashi M, Shimada H, Miyazaki K
International journal of cancer   76(6) 812-816   1998年6月   [査読有り]
Kato Y, Nagashima Y, Koshikawa N, Miyagi Y, Yasumitsu H, Miyazaki K
European journal of cancer (Oxford, England : 1990)   34(7) 1117-1123   1998年6月   [査読有り]
Inhibitory effect of matrilysin antisense oligonucleotides on human colon cancer cell invasion in vitro.
Momiyama N, Koshikawa N, Ishikawa T, Ichikawa Y, Hasegawa S, Nagashima Y, Mitsuhashi M, Miyazaki K, Shimada H
Molecular carcinogenesis   22(1) 57-63   1998年5月   [査読有り]
Hirahara F, Miyagi E, Nagashima Y, Miyagi Y, Yasumitsu H, Koshikawa N, Nakatani Y, Nakazawa T, Udagawa K, Kitamura H, Minaguchi H, Miyazaki K
Gynecologic oncology   68(2) 162-165   1998年2月   [査読有り]
Yamakawa T, Miyata S, Ogawa N, Koshikawa N, Yasumitsu H, Kanamori T, Miyazaki K
Biochimica et biophysica acta   1395(2) 202-208   1998年1月   [査読有り]
Mizushima H, Koshikawa N, Moriyama K, Takamura H, Nagashima Y, Hirahara F, Miyazaki K
Hormone research   50 Suppl 2 7-14   1998年   [査読有り]
Matrilysin gene expression in sporadic and familial colorectal adenomas.
Takeuchi N, Ichikawa Y, Ishikawa T, Momiyama N, Hasegawa S, Nagashima Y, Miyazaki K, Koshikawa N, Mitsuhashi M, Shimada H
Molecular carcinogenesis   19(4) 225-229   1997年8月   [査読有り]
Nagashima Y, Hasegawa S, Koshikawa N, Taki A, Ichikawa Y, Kitamura H, Misugi K, Kihira Y, Matuo Y, Yasumitsu H, Miyazaki K
International journal of cancer   72(3) 441-445   1997年7月   [査読有り]
Koshikawa N, Nagashima Y, Miyagi Y, Mizushima H, Yanoma S, Yasumitsu H, Miyazaki K
FEBS letters   409(3) 442-448   1997年6月   [査読有り]
Kawano N, Osawa H, Ito T, Nagashima Y, Hirahara F, Inayama Y, Nakatani Y, Kimura S, Kitajima H, Koshikawa N, Miyazaki K, Kitamura H
Human pathology   28(5) 613-622   1997年5月   [査読有り]
Miyagi Y, Yasumitsu H, Mizushima H, Koshikawa N, Matsuda Y, Itoh H, Hori TA, Aoki I, Misugi K, Miyazaki K
DNA and cell biology   15(11) 947-954   1996年11月   [査読有り]
Suzuki A, Enari M, Hayashi Y, Ohta Y, Koshikawa N, Miyazaki K, Iguchi T
Reproductive toxicology (Elmsford, N.Y.)   10(2) 129-135   1996年3月   [査読有り]
Purification and identification of a novel and four known serine proteinase inhibitors secreted by human glioblastoma cells.
Koshikawa N, Nakamura T, Tsuchiya N, Isaji M, Yasumitsu H, Umeda M, Miyazaki K
Journal of biochemistry   119(2) 334-339   1996年2月   [査読有り]
Hirahara F, Miyagi Y, Miyagi E, Yasumitsu H, Koshikawa N, Nagashima Y, Kitamura H, Minaguchi H, Umeda M, Miyazaki K
International journal of cancer   63(2) 176-181   1995年10月   [査読有り]
Miyagi E, Yasumitsu H, Hirahara F, Minaguchi H, Koshikawa N, Miyazaki K, Umeda M
Japanese journal of cancer research : Gann   86(6) 568-576   1995年6月   [査読有り]
Selective localization of gelatinase A, an enzyme degrading beta-amyloid protein, in white matter microglia and in Schwann cells.
Yamada T, Miyazaki K, Koshikawa N, Takahashi M, Akatsu H, Yamamoto T
Acta neuropathologica   89(3) 199-203   1995年   [査読有り]
cDNA cloning and mRNA expression of a serine proteinase inhibitor secreted by cancer cells: identification as placental protein 5 and tissue factor pathway inhibitor-2.
Miyagi Y, Koshikawa N, Yasumitsu H, Miyagi E, Hirahara F, Aoki I, Misugi K, Umeda M, Miyazaki K
Journal of biochemistry   116(5) 939-942   1994年11月   [査読有り]
Identification of one- and two-chain forms of trypsinogen 1 produced by a human gastric adenocarcinoma cell line.
Koshikawa N, Yasumitsu H, Nagashima Y, Umeda M, Miyazaki K
The Biochemical journal   303 ( Pt 1) 187-190   1994年10月   [査読有り]
Purification and characterization of a two-chain form of tissue inhibitor of metalloproteinases (TIMP) type 2 and a low molecular weight TIMP-like protein.
Miyazaki K, Funahashi K, Numata Y, Koshikawa N, Akaogi K, Kikkawa Y, Yasumitsu H, Umeda M
The Journal of biological chemistry   268(19) 14387-14393   1993年7月   [査読有り]
Multiple secretion of matrix serine proteinases by human gastric carcinoma cell lines.
Koshikawa N, Yasumitsu H, Umeda M, Miyazaki K
Cancer research   52(18) 5046-5053   1992年9月   [査読有り]
Miyazaki K, Umenishi F, Funahashi K, Koshikawa N, Yasumitsu H, Umeda M
Biochemical and biophysical research communications   185(3) 852-859   1992年6月   [査読有り]