永田雅大 (Masahiro Nagata) - 論文

A shorter splicing isoform antagonizes ZBP1 to modulate cell death and inflammatory responses.

Masahiro Nagata, Yasmin Carvalho Schäfer, Laurens Wachsmuth, Manolis Pasparakis

The EMBO journal 2024年9月19日

ADAR1 averts fatal type I interferon induction by ZBP1.

Huipeng Jiao, Laurens Wachsmuth, Simone Wolf, Juliane Lohmann, Masahiro Nagata, Göksu Gökberk Kaya, Nikos Oikonomou, Vangelis Kondylis, Manuel Rogg, Martin Diebold …

Nature 607(7920) 776-783 2022年7月

Helicobacter pylori metabolites exacerbate gastritis through C-type lectin receptors.

Masahiro Nagata, Kenji Toyonaga, Eri Ishikawa, Shojiro Haji, Nobuyuki Okahashi, Masatomo Takahashi, Yoshihiro Izumi, Akihiro Imamura, Koichi Takato, Hideharu Ishida …

The Journal of experimental medicine 218(1) 2021年1月4日

Design of potent Mincle signalling agonists based on an alkyl β-glucoside template.

Dylan G M Smith, Yuki Hosono, Masahiro Nagata, Sho Yamasaki, Spencer J Williams

Chemical communications (Cambridge, England) 56(31) 4292-4295 2020年4月21日

Autophosphorylation at serine 166 regulates RIP kinase 1-mediated cell death and inflammation.

Lucie Laurien, Masahiro Nagata, Hannah Schünke, Tom Delanghe, Janica L Wiederstein, Snehlata Kumari, Robin Schwarzer, Teresa Corona, Marcus Krüger, Mathieu J M Bertrand …

Nature communications 11(1) 1747-1747 2020年4月8日

High affinity sugar ligands of C-type lectin receptor langerin.

Fumi Ota, Tetsuya Hirayama, Yasuhiko Kizuka, Yoshiki Yamaguchi, Reiko Fujinawa, Masahiro Nagata, Hendra S Ismanto, Bernd Lepenies, Jonas Aretz, Christoph Rademacher …

Biochimica et biophysica acta. General subjects 1862(7) 1592-1601 2018年7月

Mincle: 20 years of a versatile sensor of insults.

Xiuyuan Lu, Masahiro Nagata, Sho Yamasaki

International immunology 30(6) 233-239 2018年5月24日

Lipidated Brartemicin Analogues Are Potent Th1-Stimulating Vaccine Adjuvants.

Amy J Foster, Masahiro Nagata, Xiuyuan Lu, Amy T Lynch, Zakaria Omahdi, Eri Ishikawa, Sho Yamasaki, Mattie S M Timmer, Bridget L Stocker

Journal of medicinal chemistry 61(3) 1045-1060 2018年2月8日

Intracellular metabolite β-glucosylceramide is an endogenous Mincle ligand possessing immunostimulatory activity.

Masahiro Nagata, Yoshihiro Izumi, Eri Ishikawa, Ryoko Kiyotake, Rieko Doi, Satoru Iwai, Zakaria Omahdi, Toshiyuki Yamaji, Tomofumi Miyamoto, Takeshi Bamba …

Proceedings of the National Academy of Sciences of the United States of America 114(16) E3285-E3294 2017年4月18日

Lipid structure influences the ability of glucose monocorynomycolate to signal through Mincle.

Phillip L van der Peet, Masahiro Nagata, Sayali Shah, Jonathan M White, Sho Yamasaki, Spencer J Williams

Organic & biomolecular chemistry 14(39) 9267-9277 2016年10月4日

Total synthesis of a cyclopropane-fatty acid α-glucosyl diglyceride from Lactobacillus plantarum and identification of its ability to signal through Mincle.

Sayali Shah, Masahiro Nagata, Sho Yamasaki, Spencer J Williams

Chemical communications (Cambridge, England) 52(72) 10902-5 2016年9月18日

Pathogen-sensing by mincle: Function and molecular aspects

Masahiro Nagata, Zakaria Omahdi, Sho Yamasaki

C-Type Lectin Receptors in Immunity 15-34 2016年1月1日査読有り

Macrophage-inducible C-type lectin Mincle-expressing dendritic cells contribute to control of splenic Mycobacterium bovis BCG infection in mice.

Friederike Behler, Regina Maus, Jennifer Bohling, Sarah Knippenberg, Gabriele Kirchhof, Masahiro Nagata, Danny Jonigk, Nicole Izykowski, Lavinia Mägel, Tobias Welte …

Infection and immunity 83(1) 184-96 2015年1月