2010年9月
Risk assessment of airborne fine particles and nanoparticles
ADVANCED POWDER TECHNOLOGY
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- 巻
- 21
- 号
- 5
- 開始ページ
- 507
- 終了ページ
- 512
- 記述言語
- 英語
- 掲載種別
- 書評論文,書評,文献紹介等
- DOI
- 10.1016/j.apt.2010.05.004
- 出版者・発行元
- ELSEVIER SCIENCE BV
Pulmonary health effects of fine particles and nanoparticles are overviewed in this paper, mainly based on the researches conducting in our laboratory. For the hazard assessment, we exposed rats to aerosolized asbestos-substitutes or nanoparticles aerosols (nickel oxide and titanium dioxide), and examined the biological and pathological effects of the particle on lung, a major target organ for the particles, and cytokines which are related to inflammation, fibrosis and carcinogenesis in the lung. It is essential to perform comprehensive evaluation of the toxicity of poorly soluble powder samples using the precise characterization data and exposure methods, such as single instillation or aerosol inhalation. (c) 2010 The Society of Powder Technology Japan. Published by Elsevier B.V. and The Society of Powder Technology Japan. All rights reserved.
- リンク情報
- ID情報
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- DOI : 10.1016/j.apt.2010.05.004
- ISSN : 0921-8831
- Web of Science ID : WOS:000283109700001