論文

査読有り
2018年2月15日

Imaging of monochromatic beams by measuring secondary electron bremsstrahlung for carbon-ion therapy using a pinhole x-ray camera

Physics in Medicine and Biology
  • Mitsutaka Yamaguchi
  • ,
  • Yuto Nagao
  • ,
  • Koki Ando
  • ,
  • Seiichi Yamamoto
  • ,
  • Makoto Sakai
  • ,
  • Raj Kumar Parajuli
  • ,
  • Kazuo Arakawa
  • ,
  • Naoki Kawachi

63
4
開始ページ
045016
終了ページ
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1088/1361-6560/aaa17c
出版者・発行元
Institute of Physics Publishing

A feasibility study on the imaging of monochromatic carbon-ion beams for carbon-ion therapy was performed. The evaluation was based on Monte Carlo simulations and beam-irradiation experiments, using a pinhole x-ray camera, which measured secondary electron bremsstrahlung (SEB). The simulation results indicated that the trajectories of the carbon-ion beams with injection energies of 278, 249 and 218 MeV/u in a water phantom, were clearly imaged by measuring the SEB with energies from 30 to 60 keV, using a pinhole camera. The Bragg-peak positions for these three injection energies were located at the positions where the ratios of the counts of SEB acquisitions to the maximum counts were approximately 0.23, 0.26 and 0.29, respectively. Moreover, we experimentally demonstrated that it was possible to identify the Bragg-peak positons, at the positions where the ratios coincided with the simulation results. However, the estimated Bragg-peak positions for the injection energies of 278 and 249 MeV/u were slightly deeper than the expected positions. In conclusion, for both the simulations and experiments, we found that the 25 mm shifts in the Bragg-peak positions can be observed by this method.

リンク情報
DOI
https://doi.org/10.1088/1361-6560/aaa17c
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/29235991
ID情報
  • DOI : 10.1088/1361-6560/aaa17c
  • ISSN : 1361-6560
  • ISSN : 0031-9155
  • PubMed ID : 29235991
  • SCOPUS ID : 85042253854

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