坂下哲哉 (Tetsuya Sakashita) - マイポータル

基本情報

所属: 国立研究開発法人量子科学技術研究開発機構

J-GLOBAL ID: 201801006408366638
researchmap会員ID: B000344535

現在は、標的アイソトープ治療の治療メカニズムと線量評価を中心として研究を進めています。

論文

Immobilization of Live Caenorhabditis elegans Individuals Using an Ultra-thin Polydimethylsiloxane Microfluidic Chip with Water Retention.

Suzuki M, Sakashita T, Funayama T

Journal of visualized experiments : JoVE (145) 2019年3月査読有り
Anti-tumor effects and potential therapeutic response biomarkers in α-emitting meta-²¹¹At-astato-benzylguanidine therapy for malignant pheochromocytoma explored by RNA-sequencing.

Ohshima Y, Kono N, Yokota Y, Watanabe S, Sasaki I, Ishioka NS, Sakashita T, Arakawa K

Theranostics 9(6) 1538-1549 2019年査読有り
A biologically based mathematical model for spontaneous and ionizing radiation cataractogenesis.

Sakashita T, Sato T, Hamada N

PloS one 14(8) e0221579 2019年査読有り
Development of ultra-thin chips for immobilization of Caenorhabditis elegans in microfluidic channels during irradiation and selection of buffer solution to prevent dehydration

Michiyo Suzuki, Tetsuya Sakashita, Yuya Hattori, Yuichiro Yokota, Yasuhiko Kobayashi, Tomoo Funayama

Journal of Neuroscience Methods 306 32-37 2018年8月1日査読有り
Antitumor effects of radionuclide treatment using α-emitting meta-²¹¹At-astato-benzylguanidine in a PC12 pheochromocytoma model.

Ohshima Y, Sudo H, Watanabe S, Nagatsu K, Tsuji AB, Sakashita T, Ito YM, Yoshinaga K, Higashi T, Ishioka NS

European journal of nuclear medicine and molecular imaging 45(6) 999-1010 2018年6月1日査読有り
Rational evaluation of the therapeutic effect and dosimetry of auger electrons for radionuclide therapy in a cell culture model

Ayaka Shinohara, Hirofumi Hanaoka, Tetsuya Sakashita, Tatsuhiko Sato, Aiko Yamaguchi, Noriko S. Ishioka, Yoshito Tsushima

Annals of Nuclear Medicine 32(2) 114-122 2018年2月1日査読有り
Region-specific irradiation system with heavy-ion microbeam for active individuals of Caenorhabditis elegans.

Suzuki M, Hattori Y, Sakashita T, Yokota Y, Kobayashi Y, Funayama T

Journal of radiation research 58(6) 881-886 2017年11月査読有り
Genetic background of enhanced radioresistance in an anhydrobiotic insect: transcriptional response to ionizing radiations and desiccation

Alina Ryabova, Kyosuke Mukae, Alexander Cherkasov, Richard Cornette, Elena Shagimardanova, Tetsuya Sakashita, Takashi Okuda, Takahiro Kikawada, Oleg Gusev

EXTREMOPHILES 21(1) 109-120 2017年1月査読有り
Dependence of the bystander effect for micronucleus formation on dose of heavy-ion radiation in normal human fibroblasts

Yoshitaka Matsumoto, Nobuyuki Hamada, Mizuho Aoki-Nakano, Tomoo Funayama, Tetsuya Sakashita, Seiichi Wada, Takehiko Kakizaki, Yasuhiko Kobayashi, Yoshiya Furusawa

RADIATION PROTECTION DOSIMETRY 166(1-4) 152-156 2015年9月査読有り
A branching process model for the analysis of abortive colony size distributions in carbon ion-irradiated normal human fibroblasts

Tetsuya Sakashita, Nobuyuki Hamada, Isao Kawaguchi, Takamitsu Hara, Yasuhiko Kobayashi, Kimiaki Saito

JOURNAL OF RADIATION RESEARCH 55(3) 423-431 2014年5月査読有り
A Framework for Analysis of Abortive Colony Size Distributions Using a Model of Branching Processes in Irradiated Normal Human Fibroblasts

Tetsuya Sakashita, Nobuyuki Hamada, Isao Kawaguchi, Noriyuki B. Ouchi, Takamitsu Hara, Yasuhiko Kobayashi, Kimiaki Saito

PLOS ONE 8(7) e70291 2013年7月査読有り
Innate Immune Genes Including a Mucin-Like Gene, mul-1, Induced by Ionizing Radiation in Caenorhabditis elegans

Takafumi Kimura, Takako Takanami, Tetsuya Sakashita, Seiichi Wada, Yasuhiko Kobayashi, Atsushi Higashitani

RADIATION RESEARCH 178(4) 313-320 2012年10月査読有り
Tolerance of Anhydrobiotic Eggs of the Tardigrade Ramazzottius varieornatus to Extreme Environments

Daiki D. Horikawa, Ayami Yamaguchi, Tetsuya Sakashita, Daisuke Tanaka, Nobuyuki Hamada, Fumiko Yukuhiro, Hirokazu Kuwahara, Takekazu Kunieda, Masahiko Watanabe, Yuichi Nakahara …

ASTROBIOLOGY 12(4) 283-289 2012年4月査読有り
Evaluation of the Relative Biological Effectiveness of Carbon Ion Beams in the Cerebellum Using the Rat Organotypic Slice Culture System

Yukari Yoshida, Yoshiyuki Suzuki, Wael S. Al-Jahdari, Nobuyuki Hamada, Tomoo Funayama, Katsuyuki Shirai, Hiroyuki Katoh, Tetsuya Sakashita, Yasuhiko Kobayashi, Takashi Nakano

JOURNAL OF RADIATION RESEARCH 53(1) 87-92 2012年1月査読有り
Heavy ion irradiation induces autophagy in irradiated C2C12 myoblasts and their bystander cells

Mizuki Hino, Nobuyuki Hamada, Yuki Tajika, Tomoo Funayama, Yoshihiro Morimura, Tetsuya Sakashita, Yuichiro Yokota, Kana Fukamoto, Yasuko Mutou, Yasuhiko Kobayashi …

JOURNAL OF ELECTRON MICROSCOPY 59(6) 495-501 2010年12月査読有り
Anhydrobiosis-Associated Nuclear DNA Damage and Repair in the Sleeping Chironomid: Linkage with Radioresistance

Oleg Gusev, Yuichi Nakahara, Veronica Vanyagina, Ludmila Malutina, Richard Cornette, Tetsuya Sakashita, Nobuyuki Hamada, Takahiro Kikawada, Yasuhiko Kobayashi, Takashi Okuda

PLOS ONE 5(11) e14008 2010年11月査読有り
Radiation Biology of Caenorhabditis elegans: Germ Cell Response, Aging and Behavior

Tetsuya Sakashita, Takako Takanami, Sumino Yanase, Nobuyuki Hamada, Michiyo Suzuki, Takafumi Kimura, Yasuhiko Kobayashi, Naoaki Ishii, Atsushi Higashitani

JOURNAL OF RADIATION RESEARCH 51(2) 107-121 2010年3月査読有り
Computational Inferences on Alteration of Neurotransmission in Chemotaxis Learning in Caenorhabditis elegans.

Michiyo Suzuki, Tetsuya Sakashita, Toshio Tsuji, Yasuhiko Kobayashi

Artificial Neural Networks - ICANN 2010 - 20th International Conference, Thessaloniki, Greece, September 15-18, 2010, Proceedings, Part I 291-300 2010年査読有り
Targeted Heavy-Ion Microbeam Irradiation of the Embryo But Not Yolk in the Diapause-Terminated Egg of the Silkworm, Bombyx mori, Induces The Somatic Mutation

Toshiharu Furusawa, Kana Fukamoto, Tetsuya Sakashita, Eiko Suzuki, Takehiko Kakizaki, Nobuyuki Hamada, Tomoo Funayama, Hiromi Suzuki, Noriaki Ishioka, Seiichi Wada …

JOURNAL OF RADIATION RESEARCH 50(4) 371-375 2009年7月査読有り
Effects of Ionizing Radiation on Locomotory Behavior and Mechanosensation in Caenorhabditis elegans

Michiyo Suzuki, Tetsuya Sakashita, Sumino Yanase, Masahiro Kikuchi, Hirofumi Ohba, Atsushi Higashitani, Nobuyuki Hamada, Tomoo Funayama, Kana Fukamoto, Toshio Tsuji …

JOURNAL OF RADIATION RESEARCH 50(2) 119-125 2009年3月査読有り

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