Satoshi Yoshinaga

Profile Information

Affiliation: Department of Anatomy, The Jikei University School of Medicine

Degree: PhD(Keio University)

Researcher number: 10885875
ORCID ID: https://orcid.org/0000-0002-7272-1558
J-GLOBAL ID: 201701003378413958
researchmap Member ID: B000281909

A psychiatrist studying developmental biology of the cerebral cortex and pathogenesis of psychiatric disorders.

Research Interests

Research Areas

Research History

Apr, 2021 - Present

School of Medicine Department of Anatomy, Keio University
Apr, 2021 - Present

Assistant Professor, Department of Anatomy, Jikei University School of Medicine
Apr, 2020 - Mar, 2021

Researcher, Department of Anatomy, Keio University School of Medicine
Apr, 2014 - Mar, 2016

Department of Neuropsychiatry, Keio University Hospital
Apr, 2012 - Mar, 2014

Keio University Hospital

Education

Apr, 2016 - Mar, 2020

PhD course, Department of Anatomy, Keio University School of Medicine

Committee Memberships

Jan, 2016 - Present

Trainee Advisory Board, Acta Psychiatrica Scandinavica

Major Papers

A single-cell atlas of transcribedcis-regulatory elements in the human genome

Jonathan Moody, Tsukasa Kouno, Miki Kojima, Ikuko Koya, Julio Leon, Akari Suzuki, Akira Hasegawa, Taishin Akiyama, Nobuko Akiyama, Masayuki Amagai …

bioRxiv, Nov 14, 2023
Spatial transcriptomics for;psychiatric research

Satoshi Yoshinaga, Ken-ichiro Kubo

53(2) 193-197, Feb, 2023 Lead author
A Unique "Reversed" Migration of Neurons in the Developing Claustrum.

Kota Oshima, Satoshi Yoshinaga, Ayako Kitazawa, Yuki Hirota, Kazunori Nakajima, Ken-Ichiro Kubo

The Journal of neuroscience : the official journal of the Society for Neuroscience, 43(5) 693-708, Feb 1, 2023
Rhythmic activation of excitatory neurons in the mouse frontal cortex improves the prefrontal cortex-mediated cognitive function.

Debabrata Hazra, Satoshi Yoshinaga, Keitaro Yoshida, Norio Takata, Kenji F Tanaka, Ken-Ichiro Kubo, Kazunori Nakajima

Cerebral cortex (New York, N.Y. : 1991), 32(23) 5243-5258, Nov 21, 2022 Peer-reviewed
Dab1-deficient deep layer neurons prevent Dab1-deficient superficial layer neurons from entering the cortical plate

Satoshi Yoshinaga, Takao Honda, Ken-ichiro Kubo, Kazunori Nakajima

Neuroscience Research, 180 23-35, Jul, 2022 Peer-reviewedLead author
Comprehensive characterization of migration profiles of murine cerebral cortical neurons during development using FlashTag labeling

Satoshi Yoshinaga, Minkyung Shin, Ayako Kitazawa, Kazuhiro Ishii, Masato Tanuma, Atsushi Kasai, Hitoshi Hashimoto, Ken-ichiro Kubo, Kazunori Nakajima

iScience, 24(4) 102277-102277, Apr, 2021 Peer-reviewedLead author
Two-Photon Voltage Imaging of Spontaneous Activity from Multiple Neurons Reveals Network Activity in Brain Tissue.

Binglun Li, Mariya Chavarha, Yuho Kobayashi, Satoshi Yoshinaga, Kazunori Nakajima, Michael Z Lin, Takafumi Inoue

iScience, 23(8) 101363-101363, Aug 21, 2020 Peer-reviewed
Both excitatory and inhibitory neurons transiently form clusters at the outermost region of the developing mammalian cerebral neocortex.

Minkyung Shin, Ayako Kitazawa, Satoshi Yoshinaga, Kanehiro Hayashi, Yukio Hirata, Colette Dehay, Ken-Ichiro Kubo, Kazunori Nakajima

The Journal of comparative neurology, 527(10) 1577-1597, Jul 1, 2019 Peer-reviewed
How judges decide: a statistical analysis on criminal responsibility and associated factors in cases under amphetamine use in Japan.

Satoshi Yoshinaga, Yasuharu Yamamoto, Kazuhiro Ikeda, Takayuki Kakimoto, Kuramochi Tomohiro, Shun-ya Kurokawa, Minami Kosugi, Yasunori Sano, Nobuyuki Nomura, Kie Takahashi …

Japanese Journal of Forensic Mental Health, 13(1) 2-10, Mar, 2018 Peer-reviewedLead author
A crossroad of neuronal diversity to build circuitry

Satoshi Yoshinaga, Kazunori Nakajima

SCIENCE, 356(6336) 376-377, Apr, 2017 Lead author
A Phosphatidylinositol Lipids System, Lamellipodin, and Ena/VASP Regulate Dynamic Morphology of Multipolar Migrating Cells in the Developing Cerebral Cortex

Satoshi Yoshinaga, Takahiro Ohkubo, Shinji Sasaki, Mutsuo Nuriya, Yukino Ogawa, Masato Yasui, Hidenori Tabata, Kazunori Nakajima

JOURNAL OF NEUROSCIENCE, 32(34) 11643-11656, Aug, 2012 Peer-reviewedLead author
Cytoarchitecture of mouse and human subventricular zone in developing cerebral neocortex

Hidenori Tabata, Satoshi Yoshinaga, Kazunori Nakajima

EXPERIMENTAL BRAIN RESEARCH, 216(2) 161-168, Jan, 2012

Books and Other Publications

THE BODY --- Challenging the Mystery

Satoshi Yoshinaga, Kazunori Nakajima (Role: Joint author, What is special about human brains)

NHK, NHK promotion, The Asahi Shimbun, 2018

Presentations

発生過程における大脳新皮質中間帯での神経細胞の移動様式の解析

内藤礼, 笠井祐登, 吉永怜史, 北澤彩子, 仲嶋一範, 久保健一郎

第129回日本解剖学会総会・全国学術集会, Mar, 2024
Unraveling the molecular signatures of schizophrenia with spatial transcriptomics

Satoshi Yoshinaga, Julio Leon, Mizuki Hino, Yoshinari Ando, Moody Jonathan, Atsuko Nagaoka, Ayako Kitazawa, Kanehiro Hayashi, Kazunori Nakajima, Chung Chau Hon, Yasuto Kunii, Jay Shin, Ken-ichiro Kubo

Jul, 2023
Analysis of novel mouse models of brain injuries in extremely preterm infants

May, 2023
胎児期の虚血が脳のかたちや機能に与える影響の解析

久保健一郎, 園田愛莉, 角田安優, 植松優毅, 内藤礼, 稲見元太, 森本桂子, 林周宏, 吉永怜史, 北澤彩子, 井上健, 出口貴美子, 仲嶋一範

第128回日本解剖学会総会・全国学術集会シンポジウム：“脳のかたちや機能を作る神経幹細胞”（オーガナイザー：藤田幸、近藤誠）, Mar, 2023
Elucidation of migration profiles of claustral neurons during brain development

Kota Oshima, Satoshi Yoshinaga, Ayako Kitazawa, Yuki Hirota, Kazunori Nakajima, Ken-ichiro Kubo

Society for Neuroscience, Neuroscience 2022 meeting, Nov, 2022
How are the subplate neurons positioned below the cortical plate in the developing mammalian cortex?

2022
Mouse hippocampal and neocortical neurons demonstrate different migration modes during brain development

2022
Analyses of migration profiles of the claustral neurons during brain development

2022
哺乳類大脳皮質表層ニューロン移動途中におけるDab1の機能

吉永怜史, 本田岳夫, 久保健一郎, 仲嶋一範

第127回日本解剖学会総会, Mar, 2022
Investigation of the factors that determine migration mode of hippocampal or neocortical neurons by transplantation and a newly developed cell-reduced culture system

Dec, 2021
How are the subplate neurons properly positioned below the cortical plate in the developing mammalian cortex?

Sep, 2021
Elucidation of migration profiles of the claustral neurons during brain development

Jul, 2021
Analyses of migration profiles of the claustral neurons during mouse development

Mar, 2021
マウス大脳新皮質錐体細胞との比較による海馬CA1錐体細胞の移動制御要因の解明

北澤彩子, 大石康二, 吉永怜史, シンミンギョン, 林周宏, 久保健一郎, 仲嶋一範

日本解剖学会第108回関東支部学術集会, Oct 30, 2020
発生段階における虚血等による脳傷害が脳の発達に与える影響の解析

久保健一郎, 出口貴美子, 吉永怜史, 野々村美康, 大島鴻太, 高杉聡, 北澤彩子, 井上健, 仲嶋一範

第123回日本小児科学会学術集会分野別シンポジウム：“解決すべき新たな超早産児の神経疾患”（座長：出口貴美子、森岡一朗）, Aug, 2020
Two-photon voltage imaging of spontaneous activity from multiple neurons reveals network activity in brain tissue

Binglun Li, Mariya Chavarha, Yuho Kobayashi, Satoshi Yoshinaga, Kazunori Nakajima, Michael Z. Lin, Takafumi Inoue

Jul, 2020
i-Gonad法を用いて、発生期大脳皮質の細胞外環境が細胞に与える影響を効率的に解析する

吉永怜史, 本田岳夫, 根本愛子, 長谷川紘之, 大石康二, 久保健一郎, 仲嶋一範

第125回日本解剖学会総会・全国学術集会, Mar, 2020
in situ HCRによる発生期大脳皮質サブプレートの解析

根本愛子, 吉永怜史, 久保健一郎, 仲嶋一範

第125回日本解剖学会総会・全国学術集会, Mar, 2020
Clustering of neurons within the outermost region of the developing mammalian neocortex: primitive neuronal clusters

Minkyung Shin, Ayako Kitazawa, Satoshi Yoshinaga, Kanehiro Hayashi, Colette Dehay, Ken-ichiro Kubo, Kazunori Nakajima

11th Neurodevelopmental Biology Section of the Korean Society for Molecular and Cellular Biology, Jun, 2019
Findings on primitive neuronal clusters formed beneath the marginal zone of the developing mammalian neocortices

Mar, 2019

Teaching Experience

2020 - Present

Neuroanatomy (Jikei University)
2020 - Present

Gross anatomy dissection (Jikei University)
2020 - Present

Histology (Jikei University)
症候病態演習II (東京慈恵会医科大学)

Professional Memberships

Research Projects

患者死後脳の空間的発現解析とマウスモデルの融合アプローチによる精神疾患病態解明

科学研究費助成事業, 若手研究, 日本学術振興会, Apr, 2022 - Mar, 2026

吉永怜史

Profile Information

Research Interests

Research Areas

Research History

Education

Committee Memberships

Major Papers

Books and Other Publications

Presentations

Teaching Experience

Professional Memberships

Research Projects

Menu

Coauthors

Following